Items where Greenwich Author is "Lam, Dr Kevin"
Aliphatic amine oxidation, Cymantrene, H-atom capture, Quinoline oxidation, Quinoline-cymantrene conjugate, Radical cation
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Van Wyck, Stephen J. and Geiger, William E. (2017) One-electron oxidation of chloroquine, cymanquine, and related aminoquinolines in nonaqueous media. Journal of Electroanalytical Chemistry, 799. pp. 531-537. ISSN 1572-6657 (Print), 1873-2569 (Online) (doi:10.1016/j.jelechem.2017.06.041)
Anodic oxidation, Bioorganometallic, Chloroquinoline, Cymantrene, Ferroquine, Weakly coordinating anion
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2016) Synthesis and anodic electrochemistry of cymanquine and related complexes. Journal of Organometallic Chemistry, 817. pp. 15-20. ISSN 0022-328X (doi:10.1016/j.jorganchem.2016.05.009)
Anodic, electrochemistry, organic synthesis, carboxylic acid, benzoyl oxy radicals
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Anodic Activation of Aromatic Acids - A New Twist for the Kolbe Reaction. In: Nazarbayev University Chemistry Department, Astana.
CO2reactions, Electrochemistry, Nickel complexes, Phosphorus ligands, X-ray structures
Dickie, Diane A., Chacon, Brittany E., Issabekov, Alibek, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Kemp, Richard A. (2016) Nickel(II) and nickel(0) complexes of bis(diisopropylphosphino)amine: Synthesis, structure, and electrochemical activity. Inorganica Chimica Acta, 453. pp. 42-50. ISSN 0020-1693 (doi:10.1016/j.ica.2016.07.048)
Chemically modified electrodes, Covalent attachment, Ferrocenyl acetylide monolayers, Glassy carbon electrodes, Lithioacetylide, Spontaneous attachment
Sheridan, Matthew V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2015) Spontaneous attachment of lithium-activated ferrocenylalkynes to carbon and gold. Electrochemistry Communications, 52. pp. 63-66. ISSN 1388-2481 (doi:10.1016/j.elecom.2015.01.024)
Cyclic olefins, Cyclooctene, Electrolyte anions, Radical cation, Radical-substrate reaction, Tetrakis(perfluoroaryl)borate anion
Stewart, Michael P., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Chong, Daesung and Geiger, William E. (2015) Electron-transfer catalyzed cycloaddition reactions of unactivated cyclic olefins in weakly coordinating anion electrolyte. Journal of Electroanalytical Chemistry, 743. pp. 68-77. ISSN 1572-6657 (Print), 1873-2569 (Online) (doi:10.1016/j.jelechem.2015.02.001)
DFT, acetaldehyde radical, methyl formate radical, solvent effect, ionisation energy
Zeinalipour-Yazdi, Constantinos D. ORCID: https://orcid.org/0000-0002-8388-1549 and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Linear correlation of vertical ionization energies and partial charges on acetaldehyde and methyl formate radicals in various solvents. Chemical Physics Letters, 746:137311. ISSN 0009-2614 (doi:10.1016/j.cplett.2020.137311)
Deoxygenation, Electrochemical, Esters, Free radicals, Reduction
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2012) Electrochemical deoxygenation of primary alcohols. Synlett, 23 (8). pp. 1235-1239. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:10.1055/s-0031-1290778)
Deoxygenation, electrosynthesis, electrochemistry, radical
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2008) Organic electrosynthesis using toluates as simple and versatile radical precursors. Chemical Communications, 2009 (1). pp. 95-97. ISSN 1359-7345 (Print), 1364-548X (Online) (doi:10.1039/b813545b)
Deprotection, Alcohol, Electrochemistry
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2009) Chemoselective chemical and electrochemical deprotections of aromatic esters. Organic Letters, 11 (13). pp. 2752-2755. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/ol900828x)
Dimerisation, Electrochemistry, Metal-metal bonding, Metallocenophanes, Strained compounds
Russell, Andrew D., Gilroy, Joe B., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Haddow, Mairi F., Harvey, Jeremy N., Geiger, William E. and Manners, Ian (2012) Metal[BOND]metal bond formation between [n]metallocenophanes: Synthesis and characterisation of a dicarba[2]ruthenocenophanium dimer. Chemistry - A European Journal, 18 (26). pp. 8000-8003. ISSN 0947-6539 (Print), 1521-3765 (Online) (doi:10.1002/chem.201201129)
Disulfide, Oxidation, Electrochemistry
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2013) Anodic oxidation of disulfides: Detection and reactions of disulfide radical cations. Journal of Organic Chemistry, 78 (16). pp. 8020-8027. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:10.1021/jo401263z)
Electrochemistry, CO2, main group elements
Bruggen, Jessica A., Feller, Keyton D., Schickel, Henry I., Tuleushova, Nazym, Zhukush, Medet, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Barry, Brian M. and Kemp, Richard A. (2017) Synthesis and characterization of metal (M=Al or Ga) 2-phosphino (phenolate/benzenethiolate) complexes and their electrochemical behavior in the presence of CO2. Main Group Chemistry, 16 (4). pp. 307-319. ISSN 1024-1221 (Print), 1745-1167 (Online) (doi:10.3233/MGC-170245)
Electrochemistry, Electrodes, Oxidation, Porphyrins, Surface chemistry
Sheridan, Matthew V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2013) Covalent attachment of porphyrins and ferrocenes to electrode surfaces through direct anodic oxidation of terminal ethynyl groups. Angewandte Chemie - International Edition, 52 (49). pp. 12897-12900. ISSN 1433-7851 (Print), 1521-3773 (Online) (doi:10.1002/anie.201307453)
Electrochemistry, Electrons
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2015) Influence of molecular and medium effects on two-electron processes. In: Hammerich, Ole and Speiser, Bernd, (eds.) Organic Electrochemistry. CRC Press, pp. 395-431. ISBN 978-1420084016 (doi:10.1201/b19122-15)
Electrochemistry, Esters, Reduction
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2008) Using toluates as simple and versatile radical precursors. Organic Letters, 10 (13). pp. 2773-2776. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/ol800944p)
Electrochemistry, Organic synthesis, Deoxygenation
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2010) Novel electrochemical deoxygenation reaction using diphenylphosphinates. Organic Letters, 13 (3). pp. 406-409. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/ol102714s)
Electrochemistry, Organometallics, Polymers
Erhard, Maximilian, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Haddow, Mairi, Whittell, George R, Geiger, William E and Manners, Ian (2013) Polyferrocenylsilane homopolymers and diblock copolymers with pendant ruthenocenyl groups by photocontrolled ring-opening polymerisation. Polymer Chemistry, 5 (4). pp. 1264-1274. ISSN 1759-9954 (Print), 1759-9962 (Online) (doi:10.1039/c3py01232h)
Electrochemistry, catalysis, copper
Sampani, Stavroula I., Zdorichenko, Victor, Danopoulou, Marianna, Leech, Matthew C., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Abdul-Sada, Alaa, Cox, Brian, Tizzard, Graham J., Coles, Simon J., Tsipis, Athanassios and Kostakis, George E. (2019) Shedding light on the use of Cu(ii)-salen complexes in the A3 coupling reaction. Dalton Transactions, 2020:49. pp. 289-299. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/C9DT04146J)
Electrochemistry, germanium, acceptor, donnor
Zaitsev, Kirill V., Kharcheva, Anastasia V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Zhanabil, Zhaisan, Issabayeva, Guldana, Oprunenko, Yuri F., Churakov, Andrei V., Zaitseva, Galina S. and Karlov, Sergey S. (2017) Donor-acceptor molecular oligogermanes: Novel properties and structural aspects. Journal of Organometallic Chemistry. ISSN 0022-328X (doi:10.1016/j.jorganchem.2017.11.029)
Electrochemistry, medicine, drug design
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Electrifying Medicinal Chemistry. In: Presentation, University of Gent (UGent). (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Medicinal Electrochemistry - Merging the Fields. In: Presentation, 28 - 30 June 2018, Catholic University of Leuven (KUL).
Electron-transfer reactions, Organometallic chemistry, Ruthenium
Russell, Andrew D., Gilroy, Joe B., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Haddow, Mairi F., Harvey, Jeremy N., Geiger, William E. and Manners, Ian (2014) Influence of cyclopentadienyl ring-tilt on electron-transfer reactions: Redox-induced reactivity of strained 2 and 3 Ruthenocenophanes. Chemistry - A European Journal, 20 (49). pp. 16216-16227. ISSN 0947-6539 (Print), 1521-3765 (Online) (doi:10.1002/chem.201403512)
Electrosynthesis, industry, bench, scale-up, organic electrochemistry, reduction, oxidation
Leech, Matthew C., Garcia, Anthony D., Petti, Alessia, Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118 and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Organic electrosynthesis: From academia to industry. Reaction Chemistry & Engineering, 5 (6). pp. 977-990. ISSN 2058-9883 (Online) (doi:10.1039/D0RE00064G)
Electrosynthesis, medchem, sp3
Lopez, Enol, van Melis, Carlo, Martin, Raul, Petti, Alessia, Hoz, Antonio de la, Diaz-Ortiz, Angel, Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Alcazar, Jesus (2021) C(sp3)-C(sp3) bond formation via electrochemical alkoxylation and subsequent Lewis acid promoted reactions. Advanced Synthesis and Catalysis, 363 (19). pp. 4521-4525. ISSN 1615-4150 (Print), 1615-4169 (Online) (doi:10.1002/adsc.202100749)
Fluorine; electrosynthesis; Kolbe; anodic oxidation
Kiaku, Cyrille, Walsh, Jamie M., Leech, Matthew C., Poole, Darren L., Mason, Joseph, Goodall, Iain C. A., Devo, Perry and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2023) eFluorination using cheap and readily available tetrafluoroborate salts. Organic Letters, 25 (9). pp. 1353-1358. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.2c04305)
Germane, Electrochemistry, Germanium, Cyclic voltammetry
Zaitsev, Kirill V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Zhanabil, Zhaisan, Suleimen, Yerlan, Kharcheva, Anastasia V., Tafeenko, Viktor A., Oprunenko, Yuri F., Poleshchuk, Oleg Kh., Lermontova, Elmira Kh. and Churakov, Andrei V. (2016) Oligogermanes containing only electron-withdrawing substituents: Synthesis and properties. Organometallics, 36 (2). pp. 298-309. ISSN 0276-7333 (Print), 1520-6041 (Online) (doi:10.1021/acs.organomet.6b00767)
Germaniu, organometallic, mechanism, electrochemistry
Zaitsev, Kirill V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Tafeenko, Viktor A., Korlyukov, Alexander A. and Poleshchuk, Oleg Kh. (2018) Aryl oligogermanes as ligands for transition metal complexes. European Journal of Inorganic Chemistry, 2018 (45). pp. 4911-4924. ISSN 1434-1948 (Print), 1099-0682 (Online) (doi:10.1002/ejic.201801095)
Germanium, Electrochemistry, organometallics, ligand
Zaitsev, Kirill V, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Poleshchuk, Oleg Kh., Bezzubov, Stanislav I. and Churakov, Andrei V. (2019) Aryl Germanes as Ligands for transition Polymetallic Complexes: Synthesis, Structure, and Properties. European Journal of Inorganic Chemistry, 2019 (22). pp. 2750-2760. ISSN 1434-1948 (Print), 1099-0682 (Online) (doi:10.1002/ejic.201900316)
Germanium, electrochemistry, catenated compounds, semi conductors
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Oligothienyl catenated germanes and silanes: synthesis, structure, properties. Dalton Transactions, 2018 (15). pp. 5431-5444. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/C8DT00256H)
Kolbe, nootropic, medchem, pharma
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Kolbe anodic decarboxylation as a green way to access 2-pyrrolidinones. Organic Letters, 22 (5). pp. 1771-1775. ISSN 1523-7060 (doi:10.1021/acs.orglett.0c00056)
Phthalid, Anodic oxidation, Kolbe, Radicals, Electrochemistry
Hayrapetyan, Davit, Shkepu, Viacheslav, Seilkhanov, Olzhas T, Zhanabil, Zhaisan and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2017) Electrochemical synthesis of phthalides via anodic activation of aromatic carboxylic acids. Chemical Communications, 53 (60). pp. 8451-8454. ISSN 1359-7345 (Print), 1364-548X (Online) (doi:10.1039/C7CC03669H)
Reduction, Ester
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Markó, István E. (2009) Toluates: unexpectedly versatile reagents. Tetrahedron, 65 (52). pp. 10930-10940. ISSN 0040-4020 (doi:10.1016/j.tet.2009.09.111)
Surface modification
Sheridan, Matthew V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Geiger, William E. (2013) An anodic method for covalent attachment of molecules to electrodes through an ethynyl linkage. Journal of the American Chemical Society, 135 (8). pp. 2939-2942. ISSN 0002-7863 (Print), 1520-5126 (Online) (doi:10.1021/ja312405h)
Surface, Modification, Electrodes, Electrochemistry
Sheridan, Matthew V., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Sharafi, Mona, Schneebeli, Severin T. and Geiger, William E. (2016) Anodic methods for covalent attachment of ethynylferrocenes to electrode surfaces: Comparison of ethynyl activation processes. Langmuir, 32 (6). pp. 1645-1657. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:10.1021/acs.langmuir.6b00012)
X-ray analysis, Luminescence, Oligogermanes, Organic semiconductors, Silagermanes
Zaitsev, Kirill V., Tafeenko, Viktor A., Oprunenko, Yuri F., Kharcheva, Anastasia V., Zhanabil, Zhaisan, Suleimen, Yerlan, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Zaitsev, Vladimir B., Zaitseva, Anna V., Zaitseva, Galina S. and Karlov, Sergey S. (2017) Molecular oligogermanes and related compounds: Structure, optical and semiconductor properties. Chemistry - An Asian Journal, 12 (11). pp. 1240-1249. ISSN 1861-4728 (Print), 1861-471X (Online) (doi:10.1002/asia.201700151)
amines; desulfurization; disulfides; electrodes; salts, electrosynthesis
Kiaku, Cyrille, Walsh, Jamie M., Leech, Matthew C., Poole, Darren L., Mason, Joseph, Goodall, Iain C. A., Devo, Perry and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2023) Electrochemical isothiocyanation of primary amines. Organic Letters, 25 (7). pp. 1147-1150. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.3c00128)
anodic oxidation; deuteration; diimide; reduction; electrochemistry; hydrogenation
Russo, Camilla, Leech, Matthew C., Walsh, Jamie, Higham, Joe I., Giannessi, Lisa, Lambert, Emmanuelle, Kiaku, Cyrille, Poole, Darren L., Mason, Joseph, Goodall, Charles A. I., Devo, Perry, Giustiniano, Mariateresa, Radi, Marco and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2023) eHydrogenation: electrochemical Hydrogen-free hydrogenation. Angewandte Chemie International Edition:e202309563. ISSN 1433-7851 (Print), 1523-7052 (Online) (doi:10.1002/anie.202309563)
cancer, organometallics, inhibitors, melanoma
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Novel organometallic chloroquine derivative inhibits tumor growth. Journal of Cellular Biochemistry, 119 (7). pp. 5921-5933. ISSN 0730-2312 (Print), 1097-4644 (Online) (doi:10.1002/jcb.26787)
carbenes, electrosynthesis, analytical chemistry, electrochemical methods
Saab, Marina, Nelson, David J., Leech, Matthew C., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Nolan, Steven P., Nahra, Fady and Hecke, Kristof Van (2022) Reactions of N-heterocyclic carbene-based Chalcogenoureas with Halogens: a diverse range of outcomes. Dalton Transactions, 51 (9). pp. 3721-3733. ISSN 1477-9226 (Print), 1520-586X (Online) (doi:10.1039/D2DT00010E)
chemistry, drug design, organometallics
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Electrochemistry, Organometallics & Medicinal Chemistry An “out of the box” Approach to Drug Design. In: Nazarbayev University - American Chemical Society Chapter, Astana.
chemistry, electrosynthesis, electrochemistry, protecting groups, MOMCl
Luo, Xia, Ma, Xiaofeng, Lebreux, Frédéric, Markó, István E. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Electrochemical methoxymethylation of alcohols – a new, green and safe approach for the preparation of MOM ethers and other acetals. Chemical Communications, 54 (71). pp. 9969-9972. ISSN 1359-7345 (Print), 1364-548X (Online) (doi:10.1039/C8CC05843A)
cis-jasmone, electrosynthesis, organic electrochemistry, synthesis, organic chemistry, diketones
Ma, Xiaofeng, Dewez, Damien F., Du, Le, Luo, Xiya, Markó, István E. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2018) Synthesis of diketones, ketoesters and tetraketones by electrochemical oxidative decarboxylation of malonic acid derivatives: Application to the synthesis of cis-jasmone. Journal of Organic Chemistry, 83 (19). pp. 12044-12055. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:10.1021/acs.joc.8b01994)
complexes, electrochemistry, A3 coupling
Sampani, Stavroula I., Zdorichenko, Victor, Devonport, Jack, Rossini, Gioia, Leech, Matthew C., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Cox, Brian, Abdul-Sada, Alaa, Vargas, Alfredo and Kostakis, George E. (2020) Structural and electronic control of 1‐(2‐pyridyl)benzotriazole bidentate ligand in copper chemistry with application to catalysis in the A3 coupling reaction. Chemistry - A European Journal, 27 (13). pp. 4394-4400. ISSN 0947-6539 (Print), 1521-3765 (Online) (doi:10.1002/chem.202004781)
copper ligand design C−H activation catalysis radical DFT EPR propargylamines
Devonport, Jack, Sully, Lauren, Boudalis, Athanassios K., Hassell-Hart, Storm, Leech, Matthew C., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Abdul-Sada, Alaa, Tizzard, Graham J., Coles, Simon J., Spencer Evans, John, Vargas, Alfredo and Kostaki, George E. (2021) Room temperature Cu(II) radical-triggered Alkyne C−H activation. Journal of the American Chemical Society AU. ISSN 2691-3704 (Print), 2691-3704 (Online) (doi:10.1021/jacsau.1c00310)
cyanation reaction, electrochemical cyanation, anodic oxidation, electrosynthesis, flow chemistry, cyanogen bromide, cyanide source
Morlacci, Valerio, Milia, Marco, Saiter, Jérémy, Preet Bhela, Irene, Leech, Matthew C. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2024) eCyanation using 5‑Aminotetrazole as a safer electrophilic and nucleophilic cyanide source. Journal of the American Chemical Society AU. ISSN 2691-3704 (Online) (doi:10.1021/jacsau.4c00768)
cymanquine, anticancer, cancer, drug, organometallic
University of Vermont (2017) Cymanquine compounds and derivatives thereof and uses thereof. .
electrochemistry, organometallics
Musgrave, Rebecca A., Russell, Andrew D., Hailes, Rebekah L. N., Gamm, Paul R., Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Sparkes, Hazel A and Green, Jen (2021) Redox chemistry of nickelocene-based monomers and polymers. Organometallics, 40 (12). pp. 1945-1955. ISSN 0276-7333 (doi:10.1021/acs.organomet.1c00247)
electrochemistry, surface modification, organometallics
Geiger, William E, Sheridan, Matthew V, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Waterman, Rory (2019) Anodic oxidation of ethynylferrocene derivatives in homogeneous solution and following anodic deposition onto glassy carbon electrodes. ChemElectrochem, 6 (23). pp. 5880-5887. ISSN 2196-0216 (Online) (doi:10.1002/celc.201901545)
electrosynthesis, cyanation, radicals, flow
Carvalho, Mary-Ambre, Demin, Samuël, Martinez-Lamenca, Carolina, Romanov-Michailidis, Fedor, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Rombouts, Frederik and Lecomte, Morgan (2021) Expedient access to cyanated N-Heterocycles via direct flow-electrochemical C(sp2)-H activation. Chemistry - A European Journal. ISSN 0947-6539 (Print), 1521-3765 (Online) (doi:10.1002/chem.202103384)
electrosynthesis, flow, radicals, Kolbe, med chem
Quertenmont, Mathilde, Toussaint, rédéric C., Defrance, Thierry, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Markó, István E. and Riant, Olivier (2021) Continuous flow electrochemical oxidative cyclization and successive functionalization of 2-Pyrrolidinones. Organic Process Research & Development. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:10.1002/chem.202103384)
electrosynthesis, flow, radicals, isonitriles, isocyanides, tetrazoles, aminotetrazoles
Leech, Matthew C., Petti, Alessia, Tanbouza, Nour, Mastrodonato, Andrea, Goodall, Iain C. A., Ollevier, Thierry, Dobbs, Adrian P. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2021) Anodic oxidation of aminotetrazoles: a mild and safe route to Isocyanides. Organic Letters. ISSN 1523-7060 (Print), 1520-586X (Online) (doi:10.1021/acs.orglett.1c03475)
electrosynthesis, organic synthesis, electrochemistry
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential! In: Automated Synthesis Forum, 18 - 19 Nov 2019, University of Strathclyde Glasgow, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - a new tool for organic synthesis. In: Lecture at the Ecole nationale supérieure (Paris), Paris, France. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential! In: Lecture at the University of Sussex, Falmer, Sussex, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential. In: Polytechnique Paris, Paris, France. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential. In: Loughborough University Lecture Cycle, Loughborough University, Loughborough, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis for industrial applications. In: Johnson and Johnson, Val de Reuil, France. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential. In: Electrosynthesis Day at the Scripps Institute, 29 Aug 2019, Scripps Institute, La Jolla CA, USA. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis for drug discovery. In: Vernalis, Cambridge, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis - your chemistry has got potential. In: French Chemical Society Thematic Day, ENSI Caen, Caen France. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis for drug discovery. In: GSK, Stevenage, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrochemical activation of carboxylic acids. In: 24th Lakeland Symposium (Grasmere) 2019, 09 - 13 May 2019, Ambleside, UK. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Electrosynthesis as a tool for organic synthesis. In: Minakem, Lille, France. (Unpublished)
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Oxidation of carboxylic acids – new tricks for an old reaction. In: RSC Organic Division London & SE Regional Meeting 2019, 13 Feb 2019, Chatham Maritime, UK. (Unpublished)
electrosynthesis, radicals, oxycarbonyl, electrochemistry, organic chemistry
Petti, Alessia, Leech, Matthew C., Garcia, Anthony D., Goodall, Iain C.A., Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118 and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Economical, green, and safe route towards substituted lactones by anodic generation of oxycarbonyl radicals. Angewandte Chemie International Edition, 58 (45). pp. 16115-16118. ISSN 1433-7851 (Print), 1521-3773 (Online) (doi:10.1002/anie.201909922)
electrosynthesis; electrochemistry; guide; reviews
Leech, Matthew C. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2022) A practical guide to electrosynthesis. Nature Reviews Chemistry, 6 (4). pp. 275-286. ISSN 2397-3358 (Online) (doi:10.1038/s41570-022-00372-y)
electrosynthesis; electrochemistry; organic synthesis
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Minteer, Shelley D. and Poole, Darren L. (2022) Introduction to synthetic electrochemistry: new tricks for an old discipline. Organic and Biomolecular Chemistry, 21 (2). pp. 221-222. ISSN 1477-0520 (Print), 1477-0539 (Online) (doi:10.1039/D2OB90163C)
electrosynthesis; flow chemistry; industry
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Wheelhouse, Katherine M. P. (2021) Unleashing the potential to electrify process chemistry: from bench to plant. Organic Process Research & Development, 25 (12). pp. 2579-2580. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:10.1021/acs.oprd.1c00434)
electrosynthesis; natural product
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Leech, Matthew and Lennox, Alastair (2021) Electrochemistry in natural product synthesis. In: Lutz, Ackerman, (ed.) Electrochemistry in Organic Synthesis. Science of Synthesis . Thieme Verlagsgruppe, Stuttgart, New York, Delhi, Rio. ISBN 3132442127; 978-3132442122 (doi:10.1055/sos-SD-236-00280)
etherification, electrosynthesis, oxalates, oxidation, carbocation
Cyrille, Kiaku, Kaltenberger, Simon, Raydan, Daniel, Morlacci, Valerio, Claringbold, Bini, Goodall, Charles A. I., Palombi, Laura, Poole, Darren L. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2024) eEtherification: an electrochemical strategy toward the synthesis of sterically hindered dialkyl ethers from activated alcohols. Organic Letters. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.4c04093)
fluorination; alcohols; electrosynthesis; anodic oxidation
Kiaku, Cyrille, Martinage, Dorian, Sicim, Yasemin, Leech, Matthew C., Walsh, Jamie M., Poole, Darren L., Mason, Joseph, Goodall, Iain C. A., Devo, Perry and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2023) eFluorination of activated alcohols using collidinium tetrafluoroborate. Organic Letters. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.3c00976)
fluorination; carbamoyl fluoride; electrosynthesis; anodic oxidation
Pulikotil, Feba, Saiter, Jeremy, Burnett, John, Goodall, Iain C.A., Claringbold, Bini and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2024) eFluorination for the rapid synthesis of Carbamoyl fluorides from oxamic acids. Organic Letters. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.4c01605)
fluorine; electrosynthesis; Kolbe; anodic oxidation, SF5
Paquin, Jean-François, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Mastalerz, Vincent (2023) Exploration toward the synthesis of aliphatic SF5-containing compounds using the Kolbe reaction. Journal of Fluorine Chemistry, 268:110113. ISSN 0022-1139 (Print), 1523-7052 (Online) (doi:10.1016/j.jfluchem.2023.110113)
green chemistry, electrosynthesis, MOM ether, flow chemistry, flow electrochemistry, 3D printing
van Melis, Carlo G. W., Penny, Matthew R., Garcia, Anthony D., Petti, Alessia, Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118, Hilton, Stephen T. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2019) Supporting‐electrolyte‐free electrochemical methoxymethylation of alcohols using a 3D‐printed electrosynthesis continuous flow cell system. ChemElectrochem, 6 (16). pp. 4144-4148. ISSN 2196-0216 (Print), 2196-0216 (Online) (doi:10.1002/celc.201900815)
industry, electrosynthesis, electrochemistry, flow chemistry
Tanbouza, Nour, Ollevier, Thierry and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Bridging lab and industry with flow electrochemistry. iScience, 23 (11):101720. ISSN 2589-0042 (Online) (doi:10.1016/j.isci.2020.101720)
iron catalysis; NMR; paramagnetism; cycloaddition; reductive coupling
Féo, Mae, Djebbar, Faycel, Zhurkin, Fedor, Binet, Laurent, Touati, Nadia, Leech, Matthew, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Brémond, Eric and Lefèvre, Guillaume (2023) Ligand dynamics and reactivity of a non-innocent homoleptic iron complex (N,N)2Fe stabilized by phen-type ligands. Journal of Organometallic Chemistry, 999:122796. ISSN 0022-328X (Print), 1523-7052 (Online)
orthoesters, anodic oxidation, electrochemistry, electrosynthesis
Garcia, Anthony D., Leech, Matthew C., Petti, Alessia, Denis, Camille, Goodall, Iain C. A., Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118 and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Anodic oxidation of dithiane carboxylic acids: a rapid and mild 2 way to access functionalized orthoesters. Organic Letters, 22 (10). pp. 4000-4005. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:10.1021/acs.orglett.0c01324)
radials, electrosynthesis, electrochemistry, isocyanate
Petti, Alessia, Fagnan, Corentin, van Melis, Carlo G. W., Tanbouza, Nour, Garcia, Anthony D., Mastrodonato, Andrea, Leech, Matthew C., Goodall, Iain C. A., Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118, Ollevier, Thierry and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2021) Supporting-electrolyte-free anodic oxidation of oxamic acids into isocyanates: an expedient way to access ureas, carbamates, and thiocarbamates. Organic Process Research & Development, 25 (12). pp. 2614-2621. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:10.1021/acs.oprd.1c00112)
radials, electrosynthesis, electrochemistry, tetralone
Petti, Alessia, Natho, Philipp, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Parsons, Philip J. (2020) Regioselective electrochemical cyclobutanol ring expansion to 1-tetralones. European Journal of Organic Chemistry, 2021 (5). pp. 854-858. ISSN 1434-193X (Print), 1099-0690 (Online) (doi:10.1002/ejoc.202001535)
radicals, carboxylic acids, Kolbe
Leech, Matthew C. and Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2020) Electrosynthesis using carboxylic acid derivatives: new tricks for old reactions. Accounts of Chemical Research, 53 (1). pp. 121-134. ISSN 0001-4842 (Print), 1520-4898 (Online) (doi:10.1021/acs.accounts.9b00586)
radicals; electrosynthesis; electrochemistry; diazo
Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 (2022) Electrosynthesis: a practical way to access highly reactive intermediates. Synlett, 33 (20). pp. 1953-1960. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:10.1055/a-1890-9162)
Tanbouza, Nour, Petti, Alessia, Leech, Matthew C., Caron, Laurent, Walsh, Jamie, Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212 and Ollevier, Thierry (2022) Electrosynthesis of stabilized diazo compounds from hydrazones. Organic Letters, 24 (25). pp. 4665-4669. ISSN 1523-7060 (Print), 1520-586X (Online) (doi:10.1021/acs.orglett.2c01803)