APCs, BCA, CD,Enteric, GST–GFP, IPTG, immobilisation, LP, MALDI-TOF, MDA, PP, Peyer’s patch, SANS, SDS PAGE, silica, synthetic protein, VDS, vaccine, antigen presenting cells, bicinchoninic acid assay, circular dichroism, glutathione-S-transferase (GST), lamina propria, maternally derived antibodies, matrix assisted laser desorption ionisation time o, small angle neutron scattering, sodium dodecyl sulphate polyacrylamide gel electro, vaccine delivery systemsenteric, immobilisation

Pettit, Marie, Dyer, Paul D.R., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Griffiths, Peter C. ORCID: 0000-0002-6686-1271 , Alexander, Bruce, Cattoz, Beatrice, Heenan, Richard K., King, Stephen M., Schweins, Ralf, Pullen, Frank, Wicks, Stephen R. and Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 (2014) Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS). International Journal of Pharmaceutics, 468 (1-2). pp. 264-271. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2014.03.046)

ATR-FTIR, Carbosil ®, skin, methyl paraben, Ibuprofen, caffeine

Russeau, Wanessa, Mitchell, John ORCID: 0000-0003-2945-3292 , Tetteh, John, Lane, Majella E. and Hadgraft, Jonathan (2009) Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil® and human skin using ATR-FTIR and multivariate spectral analysis. International Journal of Pharmaceutics, 374 (1-2). pp. 17-25. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2009.02.018)

Alginate dressing, GST-GFP Proteins, Wound healing

Boateng, Joshua ORCID: 0000-0002-6310-729X , Momoh, Frederick, Richardson, Simon ORCID: 0000-0002-7927-0649 , Chowdhry, Babur and Mitchell, John ORCID: 0000-0003-2945-3292 (2015) Development functional characterization of alginate dressing as potential protein delivery system for wound healing. International Journal of Biological Macromolecules, 81. pp. 137-150. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2015.07.037)

Bovine haemoglobin, Circular dichroism, Thermal stability, Storage stability

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Coleman, Nichola J. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The thermal and storage stability of bovine haemoglobin by ultra violet–visible and circular dichroism spectroscopies. Journal of Pharmaceutical Analysis, 6 (4). pp. 242-248. ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2016.02.004)

Buccal drug delivery; Omeprazole; Oral films; Paediatric; Plasticiser

Khan, Sajjad, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Mitchell, John ORCID: 0000-0003-2945-3292 and Trivedi, Vivek ORCID: 0000-0001-9304-9214 (2015) Formulation, characterisation and stabilisation of buccal films for paediatric drug delivery of omeprazole. AAPS PharmSciTech: An Official Journal of the American Association of Pharmaceutical Scientists, 16 (4). pp. 800-810. ISSN 1530-9932 (Online) (doi:https://doi.org/10.1208/s12249-014-0268-7)

Buccal mucosa; Chitosan; Enzyme inhibitor; Insulin; Permeation enhancement; Xerogel

Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Pawar, Harshavardhan and Ayensu, Isaac (2014) Functional characterisation and permeation studies of lyophilised thiolated chitosan xerogels for buccal delivery of insulin. Protein & Peptide Letters, 21 (11). pp. 1163-1175. ISSN 0929-8665 (Print), 1875-5305 (Online) (doi:https://doi.org/10.2174/0929866521666140805124403)

Colloidal microgels; Microgel particles; Cotion samples; Attachment techniques

Majcen, Natasa, Mohsen, Reham, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2018) The development of a novel smart material based on colloidal microgels and cotton. Advances in Colloid and Interface Science, 256. pp. 193-202. ISSN 0001-8686 (Print), 1095-7103 (Online) (doi:https://doi.org/10.1016/j.cis.2018.04.005)

Composite films; glaucoma; HPMC; hyaluronic acid; mucoadhesion; ocular delivery; timolol

Tighsazzadeh, Mohammad, Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua ORCID: 0000-0002-6310-729X (2019) Development and evaluation of performance characteristics of timolol-loaded composite ocular films as potential delivery platform for treatment of glaucoma. International Journal of Pharmaceutics, 566. pp. 111-125. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2019.05.059)

Continuous tank reactor synthesis; Sulphobutylether β-cyclodextrins; Cyclodextrins

Mitchell, John ORCID: 0000-0003-2945-3292 , Wicks, Stephen, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Waters, Laura and Ehiwe, Tammy (2015) Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins. International Journal of Pharmaceutics, 495 (2). pp. 862-868. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.039)

Cyclodextrin

John Mitchell (US 14/333,417) (2015) WO2015008066A1: Cyclodextrin US 20150025023 A1. .

FT-Raman, PXRD, sucrose, humidity, amorphous, crystalline

Major, P.J., Cornelius, V.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Murphy, J. (2007) The implementation of FT-Raman spectroscopy to study solid state moisture induced changes in the crystallographic nature of pharmaceutical excipients - a lesson in humidity. Journal of Pharmacy and Pharmacology, 59 (S1). A38-A38. ISSN 0022-3573 (doi:https://doi.org/10.1211/002235707781849999)

Fourier transform infrared spectroscopy, skin, stratum corneum, target factor analysis, Fourier transform infrared imaging

Tetteh, J., Mader, K. T., Andanson, J.-M., McAuley, W.J., Lane, M.E., Hadgraft, J., Kazarian, S.G. and Mitchell, J. C. ORCID: 0000-0003-2945-3292 (2009) Local examination of skin diffusion using FTIR spectroscopic imaging and multivariate target factor analysis. Analytica Chimica Acta, 642 (1-2). pp. 246-256. ISSN 0003-2670 (doi:https://doi.org/10.1016/j.aca.2009.03.002)

Heckel equation; Deformation; Yield pressure; Linear regression; True density

Hooper, D., Clarke, F.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2016) A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt. Journal of Nanomedicine and Nanotechnology, 7 (381). p. 2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000381)

Human intestinal absorption (HIA), absorption, bile salt,sodium deoxycholate.

Waters, Laura J., Shokry, Dina S., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The use of bile salt micelles for the prediction of human intestinal absorption. Journal of Pharmaceutical Sciences, 105 (12). pp. 3611-3614. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2016.09.007)

ITC, Cyclodextrin complex, drug, thermodynamic, isothermal, log P, NSAID

Waters, Laura J., Bedford, Susan, Parkes, Gareth M.B. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2010) Influence of lipophilicity on drug-cyclodextrin interactions: A calorimetric study. Thermochimica Acta, 511 (1-2). pp. 102-106. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2010.07.031)

Indomethacin, Methyl-β-cyclodextrin, inclusion complexes, spray drying, supercritical carbon dioxide

Rudrangi, Shashi Ravi Suman, Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Vine, George J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Alexander, Bruce David and Wicks, Stephen Richard (2015) Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes. International Journal of Pharmaceutics, 479 (2). pp. 381-390. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.01.010)

LC-MS/MS assays

Alfazema, L.N., Richards, D.S., Gelebart, S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Achieving high accuracy and precision in LC-MS/MS assays for pharmaceutical analysis. Journal of Pharmacy and Pharmacology, 57 (S1). S47-S47. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248613)

MLC; HIA; bile salt; Pmw; lipophilicity

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2018) Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption. Biomedical Chromatography, 32 (12):e4351. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4351)

Mesoporous silica particles, carriers for protein drug delivery, protein immobilisation, γ-globulin release

Ajiboye, Adejumoke Lara, Trivedi, Vivek and Mitchell, John ORCID: 0000-0003-2945-3292 (2020) Mesoporous silica particles as potential carriers for protein drug delivery: protein immobilisation and the effect of displacer on γ-globulin release. Drug Development and Industrial Pharmacy, Drug Development and Industrial Pharmacy, 46 (4). pp. 576-586. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.1080/03639045.2020.1742141)

Michaelis-Menten parameters, isothermal flow, calorimetric data, flow calorimetry, enzymes, Michaelis-Menten kinetics

O'Neill, M.A.A., Beezer, A.E., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J. and Connor, J.A. (2004) Determination of Michaelis-Menten parameters obtained from isothermal flow calorimetric data. Thermochimica Acta, 417 (2). pp. 187-192. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.07.019)

NMR, C-13, N-15, dynamic nuclear polarisation, heteronuclear

Day, Iain, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Co-acquisition of hyperpolarised 13C and 15N NMR spectra. Magnetic Resonance in Chemistry, 45 (12). pp. 1018-1021. ISSN 0749-1581 (Print), 1097-458X (Online) (doi:https://doi.org/10.1002/mrc.2090)

Olanzapine, Solubility, Formulation, Supercritical, Green, Pharmaceutical

Rudrangi, Shashi Ravi Suman, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Wicks, Stephen Richard and Alexander, Bruce David (2015) Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties. International Journal of Pharmaceutics, 494 (1). pp. 408-416. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.08.062)

PCS, cationic poly(NIPAM/BA/4-vinylpyridine), mole fraction composition, thermodynamic parameters, thermodynamic activity, reference state

Pinkrah, Victoria T., Beezer, Anthony E., Chowdry, Babur Z., Gracia, Louise H., Cornelius, Victoria J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Castro-Lopez, Vanessa and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Swelling of cationic polyelectrolyte colloidal microgels: thermodynamic considerations. Colloids and Surfaces A: Physiochemical and Engineering Aspects, 262 (1-3). pp. 76-80. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2005.04.022)

Particle shape; Surface energy; Punch sticking; Crystal chemistry

Hooper, D., Clarke, F. C., Docherty, R., Mitchell, J. C. ORCID: 0000-0003-2945-3292 and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2017) Effects of crystal habit on the sticking propensity of ibuprofen — A case study. International Journal of Pharmaceutics, 531 (1). pp. 266-275. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.08.091)

Permeation; PDMS; Silicone; Plasma; Flux; Hydrophobicity

Waters, Laura J., Finch, Catherine V., Bhuiyan, A.K.M. Mehedi H., Hemming, Karl and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Effect of plasma surface treatment of poly (dimethylsiloxane) on the permeation of pharmaceutical compounds. Journal of Pharmaceutical Analysis, 7 (5). pp. 338-342. ISSN 2095-1779 (doi:https://doi.org/10.1016/j.jpha.2017.05.003)

Pluronics, Carbon dioxide

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John ORCID: 0000-0003-2945-3292 , Coleman, Nichola and Snowden, Martin ORCID: 0000-0002-1087-2692 (2014) Effect of pressure on the melting point of pluronics in pressurized carbon dioxide. Industrial & Engineering Chemistry Research, 53 (26). pp. 10820-10825. ISSN 0888-5885 (doi:https://doi.org/10.1021/ie501344m)

Polymers, Microgel, Fluorescence

Mohsen, R., Alexander, B. D., Richardson, S. C. W. ORCID: 0000-0002-7927-0649 , Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Diab, A. A. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2016) Design, synthesis, characterization and toxicity studies of Poly (N-Iso-Propylacrylamide-co-Lucifer Yellow) particles for drug delivery applications. Journal of Nanomedicine and Nanotechnology, 7 (2):1000363. pp. 363-372. ISSN 2157-7439 (doi:https://doi.org/10.4172/2157-7439.1000363)

Polymorphic transformation; Sulfanilamide; Diffuse reflectance visible spectroscopy; Powder X-ray diffraction; Differential scanning Calorimetry

Ehiwe, Tracy O., Alexander, Bruce D, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Waters, Laura J. (2016) Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy. Journal of Pharmaceutical Analysis, 6 (3). ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2015.12.002)

QSPR, enantiomeric excess, catalysis

Morao, I., Higginson, P.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) GRIND-based QSPR method to predict the enantiomeric excess in catalysis. Journal of Pharmacy and Pharmacology, 57 (S1). S31-S31. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248343)

Raman chemical images, univariate data processing, multivariate data processing

Sasic, Slobaban, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) A comparison of Raman chemical images produced by univariate and multivariate data processing - a simulation with an example from pharmaceutical practice. The Analyst, 129 (11). pp. 1001-1007. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B409879J)

Raman images, pharmaceutical products, 2D correlation spectroscopy

Sasic, S., Clark, D.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Analysing Raman images of pharmaceutical products by sample-sample 2D correlation spectroscopy. Journal of Pharmacy and Pharmacology, 56 (S1). p. 4. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489186)

Raman line mapping

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Raman line mapping as a fast method for analyzing pharmaceutical bead formulations. The Analyst, 130 (11). pp. 1530-1536. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B506523B)

Raman maps, pharmaceutical products, two-dimensional correlation, 2D correlation, sample-sample

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Analyzing Raman maps of pharmaceutical products by sample-sample two-dimensional correlation. Applied Spectroscopy, 59 (5). pp. 630-638. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/0003702053946047)

SMART wound dressings, matrices, molecules, networks, particles, polymers, veins, wound healing

Cornelius, Victoria J., Majcen, Natasa, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2006) Preparation of SMART wound dressings based on colloidal microgels and textile fibres. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130X (6413). Society of Photo-Optical Instrumentation Engineers (SPIE). ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712573)

Solid core drug delivery system, Supercritical fluid, Biomolecules, Fatty acids, Oral delivery

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2014) The preparation of solid core drug delivery systems (SCDDS) for the biomolecular delivery. In: 14th European Meeting on Supercritical Fluids (EMSF), 18-21 May 2014, Marseille, France.

Solvent extraction; Polycaprolactone; Nanoparticles; Supercritical carbon dioxide; Supercritical fluid extraction of emulsions

Ajiboye, Adejumoke Lara, Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Preparation of polycaprolactone nanoparticles via supercritical carbon dioxide extraction of emulsions. Drug Delivery and Translational Research. pp. 1-7. ISSN 2190-393X (Print), 2190-3948 (Online) (doi:https://doi.org/10.1007/s13346-017-0422-3)

Sulphoalkyl ether-β-cyclodextrin; Cyclodextrin; Continuous flow

Professor John Mitchell (2016) US20160024229A1 Cyclodextrin. US20160024229 A1.

Supercritical CO2, Melting point depression, Pluronics, Fatty acids

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Mitchell, John ORCID: 0000-0003-2945-3292 (2014) A study on melting point depression of fatty acids and Pluronics® in liquid or supercritical carbon dioxide. In: 14th European Meeting on Supercritical Fluids (EMSF) 2014, 18-21 May 2014, Marseille, France.

Supercritical CO2. Melting. Triblock polymer. Poloxamers

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Coleman, Nichola and Mitchell, John ORCID: 0000-0003-2945-3292 (2013) Melting behaviour of triblock polymers (poloxamers) in supercritical CO2. In: 6th INTERNATIONAL SYMPOSIUM ON HIGH PRESSURE PROCESSES TECHNOLOGY, 8-11 SEP 2013, Belgrade, Serbia. (Unpublished)

Supercritical carbon dioxide; Omeprazole; Metolose; Buccal; Paediatric; Fast dissolving film

Khan, Sajjad, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2016) Conversion of sustained release omeprazole loaded buccal films into fast dissolving strips using supercritical carbon dioxide (scCO2) processing, for potential paediatric drug delivery. European Journal of Pharmaceutical Sciences, 93. pp. 45-55. ISSN 0928-0987 (doi:https://doi.org/10.1016/j.ejps.2016.08.007)

Surfactant polymer, Non-ionic surfactant, Triblock copolymer, Propylene oxide copolymer, Ethylene oxide copolymer, Aqueous solution, Dilute solution, Phase transitions, Temperature, NMR spectrometry, Segmental movement, Experimental study, Ether copolymer

Beezer, A.E., Mitchell, J. ORCID: 0000-0003-2945-3292 , Rees, N.H., Armstrong, J., Chowdhry, B.Z., Leharne, S. and Buckton, G. (1991) NMR evidence for a novel phase transition in aqueous solutions of pluronic F87 (poloxamer 237). Journal of Chemical Research, Synopses (9). pp. 254-255. ISSN 0308-2342

accuracy, time dilemma, prediction, NMR chemical shifts, chloropyrimidines

Pérez, Manuel, Peakman, Torren M., Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Iñaki (2006) Accuracy vs time dilemma on the prediction of NMR chemical shifts: a case study (chloropyrimidines). The Journal of Organic Chemistry, 71 (8). pp. 3103-3110. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo0600149)

accuracy. precision, 5-methoxytryptamine, amitriptyline, quantitative MS/MS, chip-based nanoelectrospray

Alfazema, Louisa N., Richards, Don S., Gélébart, Sylvie, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Rapid, accurate and precise quantitative drug analysis: comparing liquid chromatography tandem mass spectrometry and chip-based nanoelectrospray ionisation mass spectrometry. European Journal of Mass Spectrometry, 11 (4). pp. 393-402. ISSN 1469-0667 (Print), 1356-1049 (Online) (doi:https://doi.org/10.1255/ejms.772)

aminopropyl column, biosurfactant, human intestinal absorption, micellar liquid chromatography, multiple linear regression, pharmacokinetics, sodium deoxycholate

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2019) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomedical Chromatography, 33 (7):e4515. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4515)

amorphous, crystalline, DRUV spectroscopy, ultraviolet-visible spectroscopy, perichromism, diffuse reflection spectroscopy, DRS

Major, Patrick J., Wicks, Stephen R., Alexander, Bruce D. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2011) Perichromism: a novel, rapid, spectroscopic technique to distinguish between amorphous and crystalline material. Applied Spectroscopy, 65 (12). pp. 1357-1362. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/11-06422)

antimicrobial properties, surface-active agents, flow calorimetry

Vine, G.J., Chowdhry, B.Z. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Antimicrobial properties of surface-active agents by flow calorimetry. Journal of Pharmacy and Pharmacology, 57 (S1). S107-S107. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248406)

antisense oligonucleotide; ASO; cytosolic delivery

Richardson, Dyer, Mitchell (2014) WO 2014203008 A1 Antisense oligonucleotide compositions. WO2014203008 A1.

base catalysed hydrolysis of methyl paraben

O'Neill, M.A.A., Beezer, A.E., Labetoulle, C., Nicolaides, L., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A., Connor, J.A., Kemp, R.B. and Olomolaiye, D. (2003) The base catalysed hydrolysis of methyl paraben: a test reaction for flow microcalorimeters used for determination of both kinetic and thermodynamic parameters. Thermochimica Acta, 399 (1-2). pp. 63-71. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00401-X)

biomolecules, oral delivery, supercritical CO2, myristic acid, haemoglobin

Trivedi, Vivek, Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2019) Myristic acid coated protein immobilised mesoporous silica particles as pH induced oral delivery system for the delivery of biomolecules. Pharmaceuticals, 12 (4):153. ISSN 1424-8247 (doi:https://doi.org/10.3390/ph12040153)

block copolymer, ethylene oxide copolymer, propylene oxide copolymer, dilute solution, phase transitions, thermodynamic analysis,

Beezer, A. E., Mitchard, N., Mitchell, J. ORCID: 0000-0003-2945-3292 , Armstrong, J. K., Chowdhry, B. Z., Leharne, S. and Buckton, G. (1992) High-sensitivity differential scanning microcalorimetry of phase transitions in dilute solutions of poly(oxyethylene)+poly(oxypropylene)+poly(oxyethylene) block copolymers. Journal of Chemical Research, Synopses (7). pp. 236-237. ISSN 0308-2342

buccal delivery, chitosan, lyophilised wafers, membrane dialysis, mucoadhesion, protein delivery

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)

calorimetry, ethylene oxide, propylene, oxide block copolymers

Armstrong, Jonathan K., Parsonage, John, Chowdhry, Babur, Leharne, Stephen, Mitchell, John ORCID: 0000-0003-2945-3292 , Beezer, Anthony, Lohner, Karl and Laggner, Peter (1993) Scanning densitometric and calorimetric studies of poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymers (poloxamers) in dilute aqueous solution. Journal of Physical Chemistry, 97 (15). pp. 3904-3909. ISSN 0022-3654 (doi:https://doi.org/10.1021/j100117a042)

catalysts, imidazolide coupling

Dunn, P.J., Hoffmann, W., Kang, Y., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) A comparison of catalysts to promote imidazolide couplings including the identification of 2-hydroxy-5-nitropyridine as a new, safe and effective catalyst. Journal of Pharmacy and Pharmacology, 57 (S1). S32-S33. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248451)

chemical modification, edible film, polysaccharide pullulan

Gibson, G.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Chemical modification of the edible film polysaccharide pullulan. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 50-51. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489249)

chirality, salt formation

Johnson, M.N., Feeder, N., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Effects of chirality on the salt formation of histidine. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 24-25. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

chitosan, drug-delivery, mucoadhesive

Ayensu, Isaac, Boateng, Joshua ORCID: 0000-0002-6310-729X and Mitchell, John ORCID: 0000-0003-2945-3292 (2010) Freeze-dried thiolated chitosan formulations for protein delivery via the buccal mucosa. In: UK PharmSci 2010 The Science of Medicines, 1-3 Sep 2010, Nottingham. UK. (Unpublished)

chitosan, drug-delivery, mucoadhesive, freeze-drying, wafers, thiolated chitosan

Ayensu, Isaac, Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua ORCID: 0000-0002-6310-729X (2010) Freeze-dried thiolated chitosan formulations for protein delivery via the buccal mucosa. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1273-1274. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/j.2042-7158.2010.01178.x)

chitosan, lyophilised wafers, mucoadhesion, buccal delivery, protein

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2011) Development and physico-mechanical characterisation of lyophilised chitosan wafers as potential protein drug delivery systems via the buccal mucosa. Colloids and Surfaces B: Biointerfaces, 91. pp. 258-265. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2011.11.004)

chitosan, thiolated chitosan, protein, wafers

Ayensu, I., Mitchell, J. ORCID: 0000-0003-2945-3292 and Boateng, J. ORCID: 0000-0002-6310-729X (2011) Formulation and evaluation of lyophilised thiolated chitosan wafers for buccal mucosal delivery of protein. In: Published Meeting Abstracts [AAPS]. The AAPS Journal, 2011 . American Association of Pharmaceutical Scientists (AAPS), Arlington, VA, USA. ISSN 1550-7416

colloidal microgels, absorption, dispersion, molecules, mouth, stomach

Cornelius, Victoria J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2006) The use of colloidal microgels for the controlled delivery of proteins and peptides. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130Y (6413). Society of Photo-Optical Instrumentation Engineers (SPIE), Bellingham, Washington USA. ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712578)

colloidal microgels, biodiesel, Karl Fischer, dispersibility, water absorbent, n-isopropylacrylamide, temperature, transesterification, copolymer, hydrogels, colloids

Nur, H., Snowden, M. J. ORCID: 0000-0002-1087-2692 , Cornelius, V. J., Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Harvey, P. J. ORCID: 0000-0001-7193-4570 and Benee, L. S. (2008) Colloidal microgel in removal of water from biodiesel. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 335 (1-3). pp. 133-137. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2008.10.049)

compositional analysis, colloidal microgels

Gracia, L.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Humphrey, M.J. (2005) The structural and compositional analysis of colloidal microgels and their development as controlled absorption/release devices. Journal of Pharmacy and Pharmacology, 57 (S1). S61-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

correlation, permeability, PDMS membrane

Lansdell-Smith, P.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hyde, R.M. (2005) Correlation of permeability through skin and a model PDMS membrane by computational chemistry. Journal of Pharmacy and Pharmacology, 57 (S1). S97-S97. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248488)

counter-current chromatography, solvent system selection, pharmaceutical, statistical approach

Dubant, Stéphane, Mathews, Ben, Higginson, Paul, Crook, Robert, Snowden, Martin ORCID: 0000-0002-1087-2692 and Mitchell, John ORCID: 0000-0003-2945-3292 (2008) Practical solvent system selection for counter-current separation of pharmaceutical compounds. Journal of Chromatography A, 1207 (1-2). pp. 190-192. ISSN 0021-9673 (doi:https://doi.org/10.1016/j.chroma.2008.08.113)

crosslinked pullulan

Gibson, G.H., Auffret, A.D., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Synthesis and characterisation of hydrophobically modified and crosslinked pullulan with enhanced viscosity characteristics. Journal of Pharmacy and Pharmacology, 57 (S1). S62-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

cyclic di-amino acid peptides, X-ray crystallography, ab initio calculations, vibrational spectra

Mendham, Andrew P., Dines, Trevor J., Withnall, Robert, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Chowdhry, Babur Z. (2009) Vibrational spectroscopic studies of the structure of di-amino acid peptides. Part II: cyclo(L-Asp-L-Asp) in the solid state and in aqueous solution. Journal of Raman Spectroscopy, 40 (11). pp. 1498-1507. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2307)

cyclic di-amino acid peptides, X-ray structure, X-ray crystallography, ab initio calculations, vibrational spectra

Mendham, Andrew P., Potter, Brian S., Palmer, Rex A., Dines, Trevor J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Withnall, Robert and Chowdhry, Babur Z. (2009) Vibrational spectra and crystal structure of the di-amino acid peptide cyclo(L-Met-L-Met): Comparison of experimental data and DFT calculations. Journal of Raman Spectroscopy, 41 (2). pp. 148-159. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2426)

dendrimers, drug carriers

Beezer, A.E., King, A.S.H., Martin, I.K., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Twyman, L.J. and Wain, C.F. (2003) Dendrimers as potential drug carriers; encapsulation of acidic hydrophobes within water soluble PAMAM derivatives. Tetrahedron, 59 (22). pp. 3873-3880. ISSN 0040-4020 (Online)

dissolution, dynamic nuclear polarization method, acquisition, relaxation, spectra, times

Day, I.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Snowden, M.J. ORCID: 0000-0002-1087-2692 and Davis, A.L. (2008) Investigation of the potential of the dissolution dynamic nuclear polarization method for general sensitivity enhancement in small-molecule NMR spectroscopy. Applied Magnetic Resonance, 34 (3-4). pp. 453-460. ISSN 0937-9347 (Print), 1613-7507 (Online) (doi:https://doi.org/10.1007/s00723-008-0122-8)

dynamic nuclear polarisation, spin-lattice relaxation, heteronuclear

Day, Iain J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times. Journal of Magnetic Resonance, 187 (2). pp. 216-224. ISSN 1090-7807 (doi:https://doi.org/10.1016/j.jmr.2007.04.015)

enantiomeric excess, asymmetric catalysis

Sciabola, Simone, Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Inaki (2005) Theoretical prediction of the enantiomeric excess in asymmetric catalysis. An alignment-independent molecular interaction field based approach. The Journal of Organic Chemistry, 70 (22). pp. 9025-9027. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo051496b)

evaporative light-scattering detector, ELSD, column liquid chromatography, detector calibration

Mathews, B.T., Higginson, P.D., Lyons, R., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Sach, N.W., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Taylor, M.R. and Wright, A.G. (2004) Improving quantitative measurements for the evaporative light scattering detector. Chromatographia, 60 (11-12). pp. 625-633. ISSN 0009-5893 (Print), 1612-1112 (Online) (doi:https://doi.org/10.1365/s10337-004-0441-3)

fatty acids, supercritical fluids, melting point depression

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Coleman, Nichola J., Douroumis, Dennis ORCID: 0000-0002-3782-0091 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2013) Study of the effect of pressure on melting behavior of saturated fatty acids in liquid or supercritical carbon dioxide. Journal of Chemical & Engineering Data, 58 (6). pp. 1861-1866. ISSN 0021-9568 (Print), 1520-5134 (Online) (doi:https://doi.org/10.1021/je400260c)

fracture toughness, nanoindentation, pharmaceutical --------------------------------------------------------------------------------

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Mechanical characterisation of powders using nanoindentation. Powder Technology, 143-4. pp. 179-185. ISSN 0032-5910 (doi:https://doi.org/10.1016/j.powtec.2004.04.012)

freeze-dried wafers, buccal delivery, chitosan

Ayensu, I., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Boateng, J.S. ORCID: 0000-0002-6310-729X (2010) Novel lyophilization cycle development of chitosan based formulation for buccal delivery using paracetamol as a model drug. The AAPS Journal, 12 (S2). ISSN 1550-7416

hot-melt extrusion, dissolution enhancement, solid dispersions, hydrophilic polymers, insoluble drugs

Maniruzzaman, M., Rana, M.M., Boateng, J. S. ORCID: 0000-0002-6310-729X , Mitchell, J. C. ORCID: 0000-0003-2945-3292 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2013) Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers. Drug Development and Industrial Pharmacy, 39 (2). pp. 218-227. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.3109/03639045.2012.670642)

hot-melt extrusion, taste masking, electronic tongue, solubility parameter

Maniruzzaman, Mohammed, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Bonnefille, Marion, Arranyos, Attila, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2011) Taste masking of paracetamol by hot-melt extrusion: An in vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 80 (2). pp. 433-442. ISSN 0939-6411 (doi:https://doi.org/10.1016/j.ejpb.2011.10.019)

identification, catalysts,imidazolide couplings, reaction conditions, kinetic modelling

Bright, Robert, Dale, David J., Dunn, Peter J., Hussain, Farhat, Kang, Ying, Mason, Clive, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) Identification of new catalysts to promote imidazolide couplings and optimisation of reaction conditions using kinetic modelling. Organic Process Research & Development, 8 (6). pp. 1054-1058. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op049874m)

isothermal microcalorimetry, hydration, Durham tube, RH perfusion, Ceftazidime

Hills, Andrew K., Gaisford, Simon, Beezer, Anthony E., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Connor, Joseph A. and Theophilus, Andrew L. (2003) Isothermal microcalorimetry as a tool to study solid-vapour interactions: design and testing of a novel hydration apparatus. Thermochimica Acta, 399 (1-2). pp. 91-98. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00449-5)

isothermal titration calorimetry, potentiometric titration, protonation, cationic colloidal microgel, 4-Vinylpyridine, co-polymer

Seidel, J., Pinkrah, V.T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Chowdhry, B.Z. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Isothermal titration calorimetric studies of the acid-base properties of poly (N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Thermochimica Acta, 414 (1). pp. 47-52. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.11.012)

kinetic data, nonisothermal reaction calorimetry

Hoffmann, Wilfried, Kang, Ying, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin ORCID: 0000-0002-1087-2692 (2007) Kinetic data by nonisothermal reaction calorimetry: a model-assisted calorimetric evaluation. Organic Process Research & Development, 11 (1). pp. 25-29. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op060144j)

micellar liquid chromatography, MLC, micelle size, partitioning, phthalate esters, thermodynamics

Waters, Laura J., Leharne, S.A., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hanrahan, J.P. (2007) Determination of micelle/water partition coefficients and associated thermodynamic data for dialkyl phthalate esters. Journal of Thermal Analysis and Calorimetry, 90 (1). pp. 283-288. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-006-7792-y)

monomer composition, co-polymer microgels, solid state Raman, NMR spectroscopy

Nur, H., Cornelius, V.J., Benée, L.S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Day, I.J. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2009) Semi-quantitative analysis of the monomer composition in co-polymer microgels using solid state Raman and NMR spectroscopy. Analyst, 134 (7). pp. 1366-1372. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B816792C)

nanoindentation, single crystals

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Dawson, N.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Predictive milling of pharmaceutical materials using nanoindentation of single crystals. Organic Process Research & Development, 8 (4). pp. 674-679. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op0300241)

paediatric, films, buccal mucosa drug delivery

Boateng, Joshua ORCID: 0000-0002-6310-729X , Mitchell, John ORCID: 0000-0003-2945-3292 , Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Khan, Sajjad (2014) Formulation and characterisation of oral thin films for buccal mucosa drug delivery for paediatric patients. In: Pharmaceutical Sciences Abstracts: Annual International Conference on Pharmaceutical Sciences. 5-8 May 2014, Athens, Greece. Athens Institute for Education and Research, Athens, Greece, pp. 30-31. ISBN 9786185065355

paediatric, films, metolose

Khan, S., Boateng, J.S. ORCID: 0000-0002-6310-729X , Okeke, O., Trivedi, V. ORCID: 0000-0001-9304-9214 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2014) Physico-chemical characterization of oral thin film for paediatric buccal drug delivery. In: APS PharmSci 2014, 8-10 Sep 2014, University of Hertfordshire, Hatfield, UK.

particle size, mechanical properties, pharmaceutical crystals

Taylor, L.J., Papadopoulos, D.G., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Influence of particle size on mechanical properties of pharmaceutical crystals. Journal of Pharmacy and Pharmacology, 56 (S1). p. 37. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489302)

particle size, surface energy

Narishetty, S., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Papadopoulos, D., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Ticehurst, M.D. (2004) Influence of particle size on surface energy components of inhalation grade lactose. Journal of Pharmacy and Pharmacology, 56 (S1). p. 22. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

pharmaceutical nanomaterials, drug delivery, solid core drug delivery systems

Mitchell, John ORCID: 0000-0003-2945-3292 and Trivedi, Vivek ORCID: 0000-0001-9304-9214 (2010) Pharmaceutical nanomaterials: the preparation of solid core drug delivery systems (SCDDS). Journal of Pharmacy and Pharmacology, 62 (10). pp. 1457-1458. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/j.2042-7158.2010.01178.x)

poloxamer, chemical structure, differential scanning calorimetry, nonhuman, temperature, pluronic f 87,

Mitchard, Neil, Beezer, Anthony, Rees, Nicolas, Mitchell, John ORCID: 0000-0003-2945-3292 , Leharne, Stephen, Chowdhry, Babur and Buckton, Graham (1990) Polyoxyethylene–polyoxypropylene block copolymers: a novel phase transition in aqueous solutions of pluronic F87 (poloxamer 237). Journal of the Chemical Society, Chemical Communications (13). pp. 900-901. ISSN 0022-4936 (doi:https://doi.org/10.1039/C39900000900)

polyelectrolyte, colloidal microgels

Pinkrah, V.T., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Seidel, J., Chowdhry, B.Z. and Fern, G.R. (2003) Physicochemical properties of poly(N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Langmuir, 19 (3). pp. 585-590. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la026283l)

polyelectrolyte, microgels, DLS, electrophoretic mobility, pH and temperature responsive swelling

Nur, H., Pinkrah, V. T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Benée, L.S. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2009) Synthesis and properties of polyelectrolyte microgel particles. Advances in Colloid and Interface Science, 158 (1-2). pp. 15-20. ISSN 0001-8686 (doi:https://doi.org/10.1016/j.cis.2009.07.008)

powder flow behaviour

Gururajan, B., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Mapping powder flow behaviour at different pharmaceutical processing stage. Journal of Pharmacy and Pharmacology, 57 (S1). S66-S66. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248604)

saturation determination, micellar systems, isothermal titration calorimetry, (ITC), micelles, partitioning, phthalate ester, sodium dodecyl sulphate

Waters, Laura.J., Leharne, S.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Saturation determination of micellar systems using isothermal titration calorimetry. Journal of Thermal Analysis and Calorimetry, 80 (1). pp. 43-47. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-005-0611-z)

silicone membranes, surfactant, temperature, paraben, skin permeability, in vitro

Waters, Laura J., Dennis, Laura, Bibi, Aisha and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2013) Surfactant and temperature effects on paraben transport through silicone membranes. Colloids and Surfaces B: Biointerfaces, 108. pp. 23-28. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2013.02.017)

smart fabrics,

Majcen, Natasa, Snowden, Martin ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Cornelius, Victoria J. and Voncina, Bojana (2005) The development of smart fabrics. Journal of Pharmacy and Pharmacology, 57 (Suppl.). S58-S58. ISSN Online ISSN: 2042-7158

sodium deoxycholate, NaDC, human intestinal absorption, %HIA, hydrogels, flow-through cells, static diffusion cells, absorption, permeation

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

sulphoalkyl ether-β-cyclodextrin, sulphoalkyl ether-β-cyclodextrin, batch sulphoalkylation reaction, continuous flow conditions

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

thermodynamic considerations, microgel swelling behavior

Pinkrah, V.T., Beezer, A.E., Chowdry, B.Z., Gracia, L.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Thermodynamic considerations of microgel swelling behavior. Langmuir, 20 (20). pp. 8531-8536. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la035765+)

thiolated-chitosan, lyophilisation, mucoadhesion, buccal delivery, protein

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) In vitro characterisation of chitosan based xerogels for potential buccal delivery of proteins. Carbohydrate Polymers, 89 (3). pp. 935-941. ISSN 0144-8617 (doi:https://doi.org/10.1016/j.carbpol.2012.04.039)

triacetin, volume study, isothermal microcalorimetry

O'Neill, M.A.A., Beezer, A.E., Deal, R.M., Morris, A.C. ORCID: 0000-0003-2945-3292 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A. and Connor, J.C. (2003) Survey of the effect of fill volume on the values for the enthalpy and rate constant derived from isothermal microcalorimetry: applications of a newly developed test reaction. Thermochimica Acta, 397 (1-2). pp. 163-169. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00270-8)

xylose, glycine, freeze-dried materials

Fei, D., Auffrett, A.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) The study of the reaction between xylose and glycine in freeze-dried materials. Journal of Pharmacy and Pharmacology, 56 (S1). S24-S24. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)