Article

Ajiboye, Adejumoke Lara, Trivedi, Vivek and Mitchell, John ORCID: 0000-0003-2945-3292 (2020) Mesoporous silica particles as potential carriers for protein drug delivery: protein immobilisation and the effect of displacer on γ-globulin release. Drug Development and Industrial Pharmacy, Drug Development and Industrial Pharmacy, 46 (4). pp. 576-586. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.1080/03639045.2020.1742141)

Trivedi, Vivek, Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2019) Myristic acid coated protein immobilised mesoporous silica particles as pH induced oral delivery system for the delivery of biomolecules. Pharmaceuticals, 12 (4):153. ISSN 1424-8247 (doi:https://doi.org/10.3390/ph12040153)

Tighsazzadeh, Mohammad, Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua ORCID: 0000-0002-6310-729X (2019) Development and evaluation of performance characteristics of timolol-loaded composite ocular films as potential delivery platform for treatment of glaucoma. International Journal of Pharmaceutics, 566. pp. 111-125. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2019.05.059)

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2019) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomedical Chromatography, 33 (7):e4515. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4515)

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2018) Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption. Biomedical Chromatography, 32 (12):e4351. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4351)

Majcen, Natasa, Mohsen, Reham, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2018) The development of a novel smart material based on colloidal microgels and cotton. Advances in Colloid and Interface Science, 256. pp. 193-202. ISSN 0001-8686 (Print), 1095-7103 (Online) (doi:https://doi.org/10.1016/j.cis.2018.04.005)

Hooper, D., Clarke, F. C., Docherty, R., Mitchell, J. C. ORCID: 0000-0003-2945-3292 and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2017) Effects of crystal habit on the sticking propensity of ibuprofen — A case study. International Journal of Pharmaceutics, 531 (1). pp. 266-275. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.08.091)

Ajiboye, Adejumoke Lara, Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Preparation of polycaprolactone nanoparticles via supercritical carbon dioxide extraction of emulsions. Drug Delivery and Translational Research. pp. 1-7. ISSN 2190-393X (Print), 2190-3948 (Online) (doi:https://doi.org/10.1007/s13346-017-0422-3)

Waters, Laura J., Finch, Catherine V., Bhuiyan, A.K.M. Mehedi H., Hemming, Karl and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Effect of plasma surface treatment of poly (dimethylsiloxane) on the permeation of pharmaceutical compounds. Journal of Pharmaceutical Analysis, 7 (5). pp. 338-342. ISSN 2095-1779 (doi:https://doi.org/10.1016/j.jpha.2017.05.003)

Waters, Laura J., Shokry, Dina S., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The use of bile salt micelles for the prediction of human intestinal absorption. Journal of Pharmaceutical Sciences, 105 (12). pp. 3611-3614. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2016.09.007)

Khan, Sajjad, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2016) Conversion of sustained release omeprazole loaded buccal films into fast dissolving strips using supercritical carbon dioxide (scCO2) processing, for potential paediatric drug delivery. European Journal of Pharmaceutical Sciences, 93. pp. 45-55. ISSN 0928-0987 (doi:https://doi.org/10.1016/j.ejps.2016.08.007)

Hooper, D., Clarke, F.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2016) A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt. Journal of Nanomedicine and Nanotechnology, 7 (381). p. 2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000381)

Mohsen, R., Alexander, B. D., Richardson, S. C. W. ORCID: 0000-0002-7927-0649 , Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Diab, A. A. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2016) Design, synthesis, characterization and toxicity studies of Poly (N-Iso-Propylacrylamide-co-Lucifer Yellow) particles for drug delivery applications. Journal of Nanomedicine and Nanotechnology, 7 (2):1000363. pp. 363-372. ISSN 2157-7439 (doi:https://doi.org/10.4172/2157-7439.1000363)

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Coleman, Nichola J. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The thermal and storage stability of bovine haemoglobin by ultra violet–visible and circular dichroism spectroscopies. Journal of Pharmaceutical Analysis, 6 (4). pp. 242-248. ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2016.02.004)

Ehiwe, Tracy O., Alexander, Bruce D, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Waters, Laura J. (2016) Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy. Journal of Pharmaceutical Analysis, 6 (3). ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2015.12.002)

Mitchell, John ORCID: 0000-0003-2945-3292 , Wicks, Stephen, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Waters, Laura and Ehiwe, Tammy (2015) Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins. International Journal of Pharmaceutics, 495 (2). pp. 862-868. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.039)

Rudrangi, Shashi Ravi Suman, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Wicks, Stephen Richard and Alexander, Bruce David (2015) Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties. International Journal of Pharmaceutics, 494 (1). pp. 408-416. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.08.062)

Boateng, Joshua ORCID: 0000-0002-6310-729X , Momoh, Frederick, Richardson, Simon ORCID: 0000-0002-7927-0649 , Chowdhry, Babur and Mitchell, John ORCID: 0000-0003-2945-3292 (2015) Development functional characterization of alginate dressing as potential protein delivery system for wound healing. International Journal of Biological Macromolecules, 81. pp. 137-150. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2015.07.037)

Rudrangi, Shashi Ravi Suman, Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Vine, George J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Alexander, Bruce David and Wicks, Stephen Richard (2015) Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes. International Journal of Pharmaceutics, 479 (2). pp. 381-390. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.01.010)

Khan, Sajjad, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Mitchell, John ORCID: 0000-0003-2945-3292 and Trivedi, Vivek ORCID: 0000-0001-9304-9214 (2015) Formulation, characterisation and stabilisation of buccal films for paediatric drug delivery of omeprazole. AAPS PharmSciTech: An Official Journal of the American Association of Pharmaceutical Scientists, 16 (4). pp. 800-810. ISSN 1530-9932 (Online) (doi:https://doi.org/10.1208/s12249-014-0268-7)

Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Pawar, Harshavardhan and Ayensu, Isaac (2014) Functional characterisation and permeation studies of lyophilised thiolated chitosan xerogels for buccal delivery of insulin. Protein & Peptide Letters, 21 (11). pp. 1163-1175. ISSN 0929-8665 (Print), 1875-5305 (Online) (doi:https://doi.org/10.2174/0929866521666140805124403)

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John ORCID: 0000-0003-2945-3292 , Coleman, Nichola and Snowden, Martin ORCID: 0000-0002-1087-2692 (2014) Effect of pressure on the melting point of pluronics in pressurized carbon dioxide. Industrial & Engineering Chemistry Research, 53 (26). pp. 10820-10825. ISSN 0888-5885 (doi:https://doi.org/10.1021/ie501344m)

Pettit, Marie, Dyer, Paul D.R., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Griffiths, Peter C. ORCID: 0000-0002-6686-1271 , Alexander, Bruce, Cattoz, Beatrice, Heenan, Richard K., King, Stephen M., Schweins, Ralf, Pullen, Frank, Wicks, Stephen R. and Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 (2014) Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS). International Journal of Pharmaceutics, 468 (1-2). pp. 264-271. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2014.03.046)

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Coleman, Nichola J., Douroumis, Dennis ORCID: 0000-0002-3782-0091 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2013) Study of the effect of pressure on melting behavior of saturated fatty acids in liquid or supercritical carbon dioxide. Journal of Chemical & Engineering Data, 58 (6). pp. 1861-1866. ISSN 0021-9568 (Print), 1520-5134 (Online) (doi:https://doi.org/10.1021/je400260c)

Waters, Laura J., Dennis, Laura, Bibi, Aisha and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2013) Surfactant and temperature effects on paraben transport through silicone membranes. Colloids and Surfaces B: Biointerfaces, 108. pp. 23-28. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2013.02.017)

Maniruzzaman, M., Rana, M.M., Boateng, J. S. ORCID: 0000-0002-6310-729X , Mitchell, J. C. ORCID: 0000-0003-2945-3292 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2013) Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers. Drug Development and Industrial Pharmacy, 39 (2). pp. 218-227. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.3109/03639045.2012.670642)

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) In vitro characterisation of chitosan based xerogels for potential buccal delivery of proteins. Carbohydrate Polymers, 89 (3). pp. 935-941. ISSN 0144-8617 (doi:https://doi.org/10.1016/j.carbpol.2012.04.039)

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)

Major, Patrick J., Wicks, Stephen R., Alexander, Bruce D. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2011) Perichromism: a novel, rapid, spectroscopic technique to distinguish between amorphous and crystalline material. Applied Spectroscopy, 65 (12). pp. 1357-1362. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/11-06422)

Maniruzzaman, Mohammed, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Bonnefille, Marion, Arranyos, Attila, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2011) Taste masking of paracetamol by hot-melt extrusion: An in vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 80 (2). pp. 433-442. ISSN 0939-6411 (doi:https://doi.org/10.1016/j.ejpb.2011.10.019)

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2011) Development and physico-mechanical characterisation of lyophilised chitosan wafers as potential protein drug delivery systems via the buccal mucosa. Colloids and Surfaces B: Biointerfaces, 91. pp. 258-265. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2011.11.004)

Mitchell, John ORCID: 0000-0003-2945-3292 and Trivedi, Vivek ORCID: 0000-0001-9304-9214 (2010) Pharmaceutical nanomaterials: the preparation of solid core drug delivery systems (SCDDS). Journal of Pharmacy and Pharmacology, 62 (10). pp. 1457-1458. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/j.2042-7158.2010.01178.x)

Ayensu, Isaac, Mitchell, John ORCID: 0000-0003-2945-3292 and Boateng, Joshua ORCID: 0000-0002-6310-729X (2010) Freeze-dried thiolated chitosan formulations for protein delivery via the buccal mucosa. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1273-1274. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/j.2042-7158.2010.01178.x)

Waters, Laura J., Bedford, Susan, Parkes, Gareth M.B. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2010) Influence of lipophilicity on drug-cyclodextrin interactions: A calorimetric study. Thermochimica Acta, 511 (1-2). pp. 102-106. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2010.07.031)

Ayensu, I., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Boateng, J.S. ORCID: 0000-0002-6310-729X (2010) Novel lyophilization cycle development of chitosan based formulation for buccal delivery using paracetamol as a model drug. The AAPS Journal, 12 (S2). ISSN 1550-7416

Mendham, Andrew P., Potter, Brian S., Palmer, Rex A., Dines, Trevor J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Withnall, Robert and Chowdhry, Babur Z. (2009) Vibrational spectra and crystal structure of the di-amino acid peptide cyclo(L-Met-L-Met): Comparison of experimental data and DFT calculations. Journal of Raman Spectroscopy, 41 (2). pp. 148-159. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2426)

Nur, H., Pinkrah, V. T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Benée, L.S. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2009) Synthesis and properties of polyelectrolyte microgel particles. Advances in Colloid and Interface Science, 158 (1-2). pp. 15-20. ISSN 0001-8686 (doi:https://doi.org/10.1016/j.cis.2009.07.008)

Mendham, Andrew P., Dines, Trevor J., Withnall, Robert, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Chowdhry, Babur Z. (2009) Vibrational spectroscopic studies of the structure of di-amino acid peptides. Part II: cyclo(L-Asp-L-Asp) in the solid state and in aqueous solution. Journal of Raman Spectroscopy, 40 (11). pp. 1498-1507. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2307)

Nur, H., Cornelius, V.J., Benée, L.S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Day, I.J. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2009) Semi-quantitative analysis of the monomer composition in co-polymer microgels using solid state Raman and NMR spectroscopy. Analyst, 134 (7). pp. 1366-1372. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B816792C)

Tetteh, J., Mader, K. T., Andanson, J.-M., McAuley, W.J., Lane, M.E., Hadgraft, J., Kazarian, S.G. and Mitchell, J. C. ORCID: 0000-0003-2945-3292 (2009) Local examination of skin diffusion using FTIR spectroscopic imaging and multivariate target factor analysis. Analytica Chimica Acta, 642 (1-2). pp. 246-256. ISSN 0003-2670 (doi:https://doi.org/10.1016/j.aca.2009.03.002)

Russeau, Wanessa, Mitchell, John ORCID: 0000-0003-2945-3292 , Tetteh, John, Lane, Majella E. and Hadgraft, Jonathan (2009) Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil® and human skin using ATR-FTIR and multivariate spectral analysis. International Journal of Pharmaceutics, 374 (1-2). pp. 17-25. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2009.02.018)

Nur, H., Snowden, M. J. ORCID: 0000-0002-1087-2692 , Cornelius, V. J., Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Harvey, P. J. ORCID: 0000-0001-7193-4570 and Benee, L. S. (2008) Colloidal microgel in removal of water from biodiesel. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 335 (1-3). pp. 133-137. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2008.10.049)

Dubant, Stéphane, Mathews, Ben, Higginson, Paul, Crook, Robert, Snowden, Martin ORCID: 0000-0002-1087-2692 and Mitchell, John ORCID: 0000-0003-2945-3292 (2008) Practical solvent system selection for counter-current separation of pharmaceutical compounds. Journal of Chromatography A, 1207 (1-2). pp. 190-192. ISSN 0021-9673 (doi:https://doi.org/10.1016/j.chroma.2008.08.113)

Day, I.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Snowden, M.J. ORCID: 0000-0002-1087-2692 and Davis, A.L. (2008) Investigation of the potential of the dissolution dynamic nuclear polarization method for general sensitivity enhancement in small-molecule NMR spectroscopy. Applied Magnetic Resonance, 34 (3-4). pp. 453-460. ISSN 0937-9347 (Print), 1613-7507 (Online) (doi:https://doi.org/10.1007/s00723-008-0122-8)

Day, Iain, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Co-acquisition of hyperpolarised 13C and 15N NMR spectra. Magnetic Resonance in Chemistry, 45 (12). pp. 1018-1021. ISSN 0749-1581 (Print), 1097-458X (Online) (doi:https://doi.org/10.1002/mrc.2090)

Waters, Laura J., Leharne, S.A., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hanrahan, J.P. (2007) Determination of micelle/water partition coefficients and associated thermodynamic data for dialkyl phthalate esters. Journal of Thermal Analysis and Calorimetry, 90 (1). pp. 283-288. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-006-7792-y)

Day, Iain J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times. Journal of Magnetic Resonance, 187 (2). pp. 216-224. ISSN 1090-7807 (doi:https://doi.org/10.1016/j.jmr.2007.04.015)

Hoffmann, Wilfried, Kang, Ying, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin ORCID: 0000-0002-1087-2692 (2007) Kinetic data by nonisothermal reaction calorimetry: a model-assisted calorimetric evaluation. Organic Process Research & Development, 11 (1). pp. 25-29. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op060144j)

Major, P.J., Cornelius, V.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Murphy, J. (2007) The implementation of FT-Raman spectroscopy to study solid state moisture induced changes in the crystallographic nature of pharmaceutical excipients - a lesson in humidity. Journal of Pharmacy and Pharmacology, 59 (S1). A38-A38. ISSN 0022-3573 (doi:https://doi.org/10.1211/002235707781849999)

Pérez, Manuel, Peakman, Torren M., Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Iñaki (2006) Accuracy vs time dilemma on the prediction of NMR chemical shifts: a case study (chloropyrimidines). The Journal of Organic Chemistry, 71 (8). pp. 3103-3110. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo0600149)

Sciabola, Simone, Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Inaki (2005) Theoretical prediction of the enantiomeric excess in asymmetric catalysis. An alignment-independent molecular interaction field based approach. The Journal of Organic Chemistry, 70 (22). pp. 9025-9027. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo051496b)

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Raman line mapping as a fast method for analyzing pharmaceutical bead formulations. The Analyst, 130 (11). pp. 1530-1536. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B506523B)

Alfazema, L.N., Richards, D.S., Gelebart, S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Achieving high accuracy and precision in LC-MS/MS assays for pharmaceutical analysis. Journal of Pharmacy and Pharmacology, 57 (S1). S47-S47. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248613)

Pinkrah, Victoria T., Beezer, Anthony E., Chowdry, Babur Z., Gracia, Louise H., Cornelius, Victoria J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Castro-Lopez, Vanessa and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Swelling of cationic polyelectrolyte colloidal microgels: thermodynamic considerations. Colloids and Surfaces A: Physiochemical and Engineering Aspects, 262 (1-3). pp. 76-80. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2005.04.022)

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Analyzing Raman maps of pharmaceutical products by sample-sample two-dimensional correlation. Applied Spectroscopy, 59 (5). pp. 630-638. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/0003702053946047)

Waters, Laura.J., Leharne, S.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Saturation determination of micellar systems using isothermal titration calorimetry. Journal of Thermal Analysis and Calorimetry, 80 (1). pp. 43-47. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-005-0611-z)

Vine, G.J., Chowdhry, B.Z. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Antimicrobial properties of surface-active agents by flow calorimetry. Journal of Pharmacy and Pharmacology, 57 (S1). S107-S107. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248406)

Lansdell-Smith, P.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hyde, R.M. (2005) Correlation of permeability through skin and a model PDMS membrane by computational chemistry. Journal of Pharmacy and Pharmacology, 57 (S1). S97-S97. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248488)

Morao, I., Higginson, P.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) GRIND-based QSPR method to predict the enantiomeric excess in catalysis. Journal of Pharmacy and Pharmacology, 57 (S1). S31-S31. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248343)

Gururajan, B., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Mapping powder flow behaviour at different pharmaceutical processing stage. Journal of Pharmacy and Pharmacology, 57 (S1). S66-S66. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248604)

Alfazema, Louisa N., Richards, Don S., Gélébart, Sylvie, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Rapid, accurate and precise quantitative drug analysis: comparing liquid chromatography tandem mass spectrometry and chip-based nanoelectrospray ionisation mass spectrometry. European Journal of Mass Spectrometry, 11 (4). pp. 393-402. ISSN 1469-0667 (Print), 1356-1049 (Online) (doi:https://doi.org/10.1255/ejms.772)

Gibson, G.H., Auffret, A.D., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Synthesis and characterisation of hydrophobically modified and crosslinked pullulan with enhanced viscosity characteristics. Journal of Pharmacy and Pharmacology, 57 (S1). S62-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

Dunn, P.J., Hoffmann, W., Kang, Y., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) A comparison of catalysts to promote imidazolide couplings including the identification of 2-hydroxy-5-nitropyridine as a new, safe and effective catalyst. Journal of Pharmacy and Pharmacology, 57 (S1). S32-S33. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248451)

Majcen, Natasa, Snowden, Martin ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Cornelius, Victoria J. and Voncina, Bojana (2005) The development of smart fabrics. Journal of Pharmacy and Pharmacology, 57 (Suppl.). S58-S58. ISSN Online ISSN: 2042-7158

Gracia, L.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Humphrey, M.J. (2005) The structural and compositional analysis of colloidal microgels and their development as controlled absorption/release devices. Journal of Pharmacy and Pharmacology, 57 (S1). S61-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

Mathews, B.T., Higginson, P.D., Lyons, R., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Sach, N.W., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Taylor, M.R. and Wright, A.G. (2004) Improving quantitative measurements for the evaporative light scattering detector. Chromatographia, 60 (11-12). pp. 625-633. ISSN 0009-5893 (Print), 1612-1112 (Online) (doi:https://doi.org/10.1365/s10337-004-0441-3)

Sasic, Slobaban, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) A comparison of Raman chemical images produced by univariate and multivariate data processing - a simulation with an example from pharmaceutical practice. The Analyst, 129 (11). pp. 1001-1007. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B409879J)

Taylor, L.J., Papadopoulos, D.G., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Influence of particle size on mechanical properties of pharmaceutical crystals. Journal of Pharmacy and Pharmacology, 56 (S1). p. 37. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489302)

Pinkrah, V.T., Beezer, A.E., Chowdry, B.Z., Gracia, L.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Thermodynamic considerations of microgel swelling behavior. Langmuir, 20 (20). pp. 8531-8536. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la035765+)

O'Neill, M.A.A., Beezer, A.E., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J. and Connor, J.A. (2004) Determination of Michaelis-Menten parameters obtained from isothermal flow calorimetric data. Thermochimica Acta, 417 (2). pp. 187-192. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.07.019)

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Mechanical characterisation of powders using nanoindentation. Powder Technology, 143-4. pp. 179-185. ISSN 0032-5910 (doi:https://doi.org/10.1016/j.powtec.2004.04.012)

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Dawson, N.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Predictive milling of pharmaceutical materials using nanoindentation of single crystals. Organic Process Research & Development, 8 (4). pp. 674-679. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op0300241)

Seidel, J., Pinkrah, V.T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Chowdhry, B.Z. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Isothermal titration calorimetric studies of the acid-base properties of poly (N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Thermochimica Acta, 414 (1). pp. 47-52. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.11.012)

Sasic, S., Clark, D.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Analysing Raman images of pharmaceutical products by sample-sample 2D correlation spectroscopy. Journal of Pharmacy and Pharmacology, 56 (S1). p. 4. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489186)

Gibson, G.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Chemical modification of the edible film polysaccharide pullulan. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 50-51. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489249)

Johnson, M.N., Feeder, N., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Effects of chirality on the salt formation of histidine. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 24-25. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

Bright, Robert, Dale, David J., Dunn, Peter J., Hussain, Farhat, Kang, Ying, Mason, Clive, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) Identification of new catalysts to promote imidazolide couplings and optimisation of reaction conditions using kinetic modelling. Organic Process Research & Development, 8 (6). pp. 1054-1058. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op049874m)

Narishetty, S., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Papadopoulos, D., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Ticehurst, M.D. (2004) Influence of particle size on surface energy components of inhalation grade lactose. Journal of Pharmacy and Pharmacology, 56 (S1). p. 22. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

Fei, D., Auffrett, A.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) The study of the reaction between xylose and glycine in freeze-dried materials. Journal of Pharmacy and Pharmacology, 56 (S1). S24-S24. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

O'Neill, M.A.A., Beezer, A.E., Labetoulle, C., Nicolaides, L., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A., Connor, J.A., Kemp, R.B. and Olomolaiye, D. (2003) The base catalysed hydrolysis of methyl paraben: a test reaction for flow microcalorimeters used for determination of both kinetic and thermodynamic parameters. Thermochimica Acta, 399 (1-2). pp. 63-71. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00401-X)

Hills, Andrew K., Gaisford, Simon, Beezer, Anthony E., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Connor, Joseph A. and Theophilus, Andrew L. (2003) Isothermal microcalorimetry as a tool to study solid-vapour interactions: design and testing of a novel hydration apparatus. Thermochimica Acta, 399 (1-2). pp. 91-98. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00449-5)

O'Neill, M.A.A., Beezer, A.E., Deal, R.M., Morris, A.C. ORCID: 0000-0003-2945-3292 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A. and Connor, J.C. (2003) Survey of the effect of fill volume on the values for the enthalpy and rate constant derived from isothermal microcalorimetry: applications of a newly developed test reaction. Thermochimica Acta, 397 (1-2). pp. 163-169. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00270-8)

Beezer, A.E., King, A.S.H., Martin, I.K., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Twyman, L.J. and Wain, C.F. (2003) Dendrimers as potential drug carriers; encapsulation of acidic hydrophobes within water soluble PAMAM derivatives. Tetrahedron, 59 (22). pp. 3873-3880. ISSN 0040-4020 (Online)

Pinkrah, V.T., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Seidel, J., Chowdhry, B.Z. and Fern, G.R. (2003) Physicochemical properties of poly(N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Langmuir, 19 (3). pp. 585-590. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la026283l)

Armstrong, Jonathan K., Parsonage, John, Chowdhry, Babur, Leharne, Stephen, Mitchell, John ORCID: 0000-0003-2945-3292 , Beezer, Anthony, Lohner, Karl and Laggner, Peter (1993) Scanning densitometric and calorimetric studies of poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymers (poloxamers) in dilute aqueous solution. Journal of Physical Chemistry, 97 (15). pp. 3904-3909. ISSN 0022-3654 (doi:https://doi.org/10.1021/j100117a042)

Beezer, A. E., Mitchard, N., Mitchell, J. ORCID: 0000-0003-2945-3292 , Armstrong, J. K., Chowdhry, B. Z., Leharne, S. and Buckton, G. (1992) High-sensitivity differential scanning microcalorimetry of phase transitions in dilute solutions of poly(oxyethylene)+poly(oxypropylene)+poly(oxyethylene) block copolymers. Journal of Chemical Research, Synopses (7). pp. 236-237. ISSN 0308-2342

Beezer, A.E., Mitchell, J. ORCID: 0000-0003-2945-3292 , Rees, N.H., Armstrong, J., Chowdhry, B.Z., Leharne, S. and Buckton, G. (1991) NMR evidence for a novel phase transition in aqueous solutions of pluronic F87 (poloxamer 237). Journal of Chemical Research, Synopses (9). pp. 254-255. ISSN 0308-2342

Mitchard, Neil, Beezer, Anthony, Rees, Nicolas, Mitchell, John ORCID: 0000-0003-2945-3292 , Leharne, Stephen, Chowdhry, Babur and Buckton, Graham (1990) Polyoxyethylene–polyoxypropylene block copolymers: a novel phase transition in aqueous solutions of pluronic F87 (poloxamer 237). Journal of the Chemical Society, Chemical Communications (13). pp. 900-901. ISSN 0022-4936 (doi:https://doi.org/10.1039/C39900000900)

Conference Proceedings

Boateng, Joshua ORCID: 0000-0002-6310-729X , Mitchell, John ORCID: 0000-0003-2945-3292 , Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Khan, Sajjad (2014) Formulation and characterisation of oral thin films for buccal mucosa drug delivery for paediatric patients. In: Pharmaceutical Sciences Abstracts: Annual International Conference on Pharmaceutical Sciences. 5-8 May 2014, Athens, Greece. Athens Institute for Education and Research, Athens, Greece, pp. 30-31. ISBN 9786185065355

Ayensu, I., Mitchell, J. ORCID: 0000-0003-2945-3292 and Boateng, J. ORCID: 0000-0002-6310-729X (2011) Formulation and evaluation of lyophilised thiolated chitosan wafers for buccal mucosal delivery of protein. In: Published Meeting Abstracts [AAPS]. The AAPS Journal, 2011 . American Association of Pharmaceutical Scientists (AAPS), Arlington, VA, USA. ISSN 1550-7416

Cornelius, Victoria J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2006) The use of colloidal microgels for the controlled delivery of proteins and peptides. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130Y (6413). Society of Photo-Optical Instrumentation Engineers (SPIE), Bellingham, Washington USA. ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712578)

Cornelius, Victoria J., Majcen, Natasa, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2006) Preparation of SMART wound dressings based on colloidal microgels and textile fibres. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130X (6413). Society of Photo-Optical Instrumentation Engineers (SPIE). ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712573)

Conference or Conference Paper

Khan, S., Boateng, J.S. ORCID: 0000-0002-6310-729X , Okeke, O., Trivedi, V. ORCID: 0000-0001-9304-9214 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2014) Physico-chemical characterization of oral thin film for paediatric buccal drug delivery. In: APS PharmSci 2014, 8-10 Sep 2014, University of Hertfordshire, Hatfield, UK.

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2014) The preparation of solid core drug delivery systems (SCDDS) for the biomolecular delivery. In: 14th European Meeting on Supercritical Fluids (EMSF), 18-21 May 2014, Marseille, France.

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Mitchell, John ORCID: 0000-0003-2945-3292 (2014) A study on melting point depression of fatty acids and Pluronics® in liquid or supercritical carbon dioxide. In: 14th European Meeting on Supercritical Fluids (EMSF) 2014, 18-21 May 2014, Marseille, France.

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Coleman, Nichola and Mitchell, John ORCID: 0000-0003-2945-3292 (2013) Melting behaviour of triblock polymers (poloxamers) in supercritical CO2. In: 6th INTERNATIONAL SYMPOSIUM ON HIGH PRESSURE PROCESSES TECHNOLOGY, 8-11 SEP 2013, Belgrade, Serbia. (Unpublished)

Ayensu, Isaac, Boateng, Joshua ORCID: 0000-0002-6310-729X and Mitchell, John ORCID: 0000-0003-2945-3292 (2010) Freeze-dried thiolated chitosan formulations for protein delivery via the buccal mucosa. In: UK PharmSci 2010 The Science of Medicines, 1-3 Sep 2010, Nottingham. UK. (Unpublished)

Patent

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

Professor John Mitchell (2016) US20160024229A1 Cyclodextrin. US20160024229 A1.

John Mitchell (US 14/333,417) (2015) WO2015008066A1: Cyclodextrin US 20150025023 A1. .

Richardson, Dyer, Mitchell (2014) WO 2014203008 A1 Antisense oligonucleotide compositions. WO2014203008 A1.