Items where Greenwich Author is "Fivaz, Marc"
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AMPA receptor; PKA; STIM1 and STIM2; endoplasmic reticulum; excitatory synapse; long-term potentiation; spatial memory
Garcia-Alvarez, Gisela, Shetty, Mahesh S., Lu, Bo, Yap, Kenrick An Fu, Oh-Hora, Masatsugu, Sajikumar, Sreedharan, Bichler, Zoƫ and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2015)
Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes.
Frontiers in Behavioral Neuroscience, 9:180.
ISSN 1662-5153 (Online)
(doi:https://doi.org/10.3389/fnbeh.2015.00180)
AMPA receptors, Endoplasmic reticulum, Synaptic plasticity, Stim2, Trafficking
Garcia-Alvarez, Gisela, Lu, Bo, Yap, Kenrick An Fu, Wong, Loo Chin, Thevathasan, Jervis Vermal, Lim, Lynette, Ji, Fang, Tan, Kia Wee, Mancuso, James J., Tang, Willcyn, Poon, Shou Yu, Augustine, Goerge J. and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2015)
STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs.
Molecular Biology of the Cell, 26 (6).
pp. 1141-1159.
ISSN 1059-1524 (Print), 1939-4586 (Online)
(doi:https://doi.org/10.1091/mbc.E14-07-1222)
Cell migration, Feedback loops, Self-assembly, Signalling, Chemical genetics
Thevathasan, Jervis Vermal, Tan, Elisabeth, Zheng, Hui, Lin, Yu-Chun, Li, Yang, Inoue, Takanari and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2013)
The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts.
Molecular Biology of the Cell, 24 (14).
pp. 2228-2237.
ISSN 1059-1524 (Print), 1939-4586 (Online)
(doi:https://doi.org/10.1091/mbc.E12-12-0905)
Endoplasmic reticulum; Excitatory synapse; Plasticity; Memory; Long-term potentiation; Long-term depression; AMPA receptors
Yap, Kenrick An Fu, Shetty, Mahesh Shivarama, Garcia-Alvarez, Gisela, Lu, Bo, Alagappan, Durgadevi, Oh-Hora, Masatsugu, Sajikumar, Sreedharan and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2016)
STIM2 regulates AMPA receptor trafficking and plasticity at hippocampal synapses.
Neurobiology of Learning and Memory, 138.
pp. 54-61.
ISSN 1074-7427
(doi:https://doi.org/10.1016/j.nlm.2016.08.007)
Image processing; microRNA (miRNA); Presynaptic terminals; Primary neuron culture; Synapse formation; Synaptic vesicles; Synaptogenic proteins
Poon, Vivian Y., Goh, Chiatzun, Voorhoeve, P. Mathijs and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2014)
High-content imaging of presynaptic assembly.
Frontiers in Cellular Neuroscience, 8.
ISSN 1662-5102 (Online)
(doi:https://doi.org/10.3389/fncel.2014.00066)
Imaging, STIM, SOCE, Segmentation Software, Image analysis
Wong, Loo Chin, Lu, Bo, Tan, Kia Wee and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2010)
Fully-automated image processing software to analyze calcium traces in populations of single cells.
Cell calcium, 48 (5).
pp. 270-4.
ISSN 1532-1991
(doi:https://doi.org/10.1016/j.ceca.2010.09.008)
Integrin, Invasion, Lamellipodia, Migration
Astro, Veronica, Chiaretti, Sara, Magistrati, Elisa, Fivaz, Marc
ORCID: 0000-0003-1003-7934
and de Curtis, Ivan
(2014)
Liprin- 1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.
Journal of Cell Science, 127 (17).
pp. 3862-3876.
ISSN 0021-9533 (Print), 1477-9137 (Online)
(doi:https://doi.org/10.1242/jcs.155663)
Oncoproteins, Transformation, Hippo pathway, YAP proto-oncogene
Nguyen, Hung Thanh, Hong, Xin, Tan, Sam, Chen, Qingfeng, Chan, Lifang, Fivaz, Marc
ORCID: 0000-0003-1003-7934
, Cohen, Stephen M. and Voorhoeve, P. Mathijs
(2014)
Viral small T oncoproteins transform cells by alleviating hippo-pathway-mediated inhibition of the YAP proto-oncogene.
Cell Reports, 8 (3).
pp. 707-713.
ISSN 2211-1247 (Print), 2211-1247 (Online)
(doi:https://doi.org/10.1016/j.celrep.2014.06.062)
SOCE, STIM, neuron, calcium imaging, endoplasmic reticulum
Lu, Bo and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2016)
Neuronal SOCE: myth or reality?
Trends in Cell Biology, 26 (12).
pp. 890-893.
ISSN 0962-8924 (Print), 1879-3088 (Online)
(doi:https://doi.org/10.1016/j.tcb.2016.09.008)
Synapse, Imaging, Fluorescent biosensors, Optogenetics
Augustine, George J. and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2016)
Editorial: Imaging synapse structure and function.
Frontiers in Synaptic Neuroscience, 8:36.
ISSN 1663-3563 (Online)
(doi:https://doi.org/10.3389/fnsyn.2016.00036)
autism; human neural progenitors; stem cells; CHD8
Coakley-Youngs, Emma, Ranatunga, Medhavi, Richardson, Simon
ORCID: 0000-0002-7927-0649
, Getti, Giulia
ORCID: 0000-0003-1402-8496
, Shorter, Susan and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2022)
Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle.
Biology Open, 11 (9):bio058941.
pp. 1-11.
ISSN 2046-6390 (Online)
(doi:https://doi.org/10.1242/bio.058941)
feedback, signalling, Ras, PI3K, neuron, differentiation
Fivaz, Marc
ORCID: 0000-0003-1003-7934
, Bandara, Samuel, Inoue, Takanari and Meyer, Tobias
(2007)
Robust neuronal symmetry breaking by Ras-triggered local positive feedback.
Current Biology, 18 (1).
pp. 44-50.
ISSN 0960-9822 (Print), 1879-0445 (Online)
(doi:https://doi.org/10.1016/j.cub.2007.11.051)
feedback, signalling, synapse, neurobiology
Li, Yang and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2008)
Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue.
BioEssays : news and reviews in molecular, cellular and developmental biology, 30 (10).
pp. 929-933.
ISSN 1521-1878 (Print), 1475-147X (Online)
(doi:https://doi.org/10.1002/bies.20824)
mammary cancer, metastatic sublines, syngeneic, spontaneous metastasis, D2A1, BALB/c
Jungwirth, Ute, van Weverwijk, Antoinette, Melake, Miriam J., Chambers, Ann F., Gao, Qiong, Fivaz, Marc
ORCID: 0000-0003-1003-7934
and Isacke, Clare M.
(2017)
Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host.
Disease models & mechanisms.
ISSN 1754-8403 (Print), 1754-8411 (Online)
(doi:https://doi.org/10.1242/dmm.031740)
miRNAs, Synapse, Transcriptome, Polycomb Group Protein, Neurotransmission, Epigenetics
Poon, Vivian Y., Gu, Minxia, Ji, Fang, VanDongen, Antonius M. and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2016)
miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1.
BMC Genomics, 17 (1):777.
ISSN 1471-2164 (Online)
(doi:https://doi.org/10.1186/s12864-016-3139-7)
synaptic vesicle cycle, neurotransmitter, synaptic transmission, DISC1, neuropsychiatric disorders
Tang, Willcyn, Thevathasan, Jervis Vermal, Lin, Qingshu, Lim, Kim Buay, Kuroda, Keisuke, Kaibuchi, Kozo, Bilger, Marcel, Soong, Tuck Wah and Fivaz, Marc
ORCID: 0000-0003-1003-7934
(2016)
Stimulation of synaptic vesicle exocytosis by the mental disease gene DISC1 is mediated by N-Type voltage-gated calcium channels.
Frontiers in Synaptic Neuroscience, 8:15.
ISSN 1663-3563 (Online)
(doi:https://doi.org/10.3389/fnsyn.2016.00015)