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Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue

Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue

Li, Yang and Fivaz, Marc ORCID: 0000-0003-1003-7934 (2008) Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue. BioEssays : news and reviews in molecular, cellular and developmental biology, 30 (10). pp. 929-933. ISSN 1521-1878 (Print), 1475-147X (Online) (doi:https://doi.org/10.1002/bies.20824)

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Abstract

Proper wiring of the nervous system requires tight control of the number of nerve terminals that innervate a target tissue. Recent work by Deppmann et al., now suggests that this is achieved by feedback-mediated neuronal competition for target-derived survival cues. The authors' model is inspired by the theory for pattern formation based on self-activation and lateral inhibition, proposed by Meinhardt and Gierer more than 30 years ago.

Item Type: Article
Uncontrolled Keywords: feedback, signalling, synapse, neurobiology
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Life & Sports Sciences
Last Modified: 19 Nov 2018 15:03
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/18512

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