(-)-Solenopsin A,(+)-epi-Dihydropinidine, aza-silyl-Prins reaction, trans-dihydropyridine

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Guesné, Sebastien J.J. (2005) [Letter] Rapid access to trans-2,6-disubstituted piperidines: expedient total syntheses of (-)-solenopsin A and (+)-epi-dihydropinidine. Synlett (13). pp. 2101-2103. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:https://doi.org/10.1055/s-2005-871956)

Elastomer; Oligomer; Total synthesis; Structure elucidation; Isophorone; Tebbe reagent; Hydrogenation

Minicone, Fabrizio, Attrill, Robin, Hodgson, Michael, Wheelhouse, Katherine and Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2018) First total synthesis and structural confirmation of C13-Butylrubber Oligomers. European Journal of Organic Chemistry, 2018 (25). pp. 3271-3275. ISSN 1434-193X (Print), 1099-0690 (Online) (doi:https://doi.org/10.1002/ejoc.201800937)

Electrosynthesis, industry, bench, scale-up, organic electrochemistry, reduction, oxidation

Leech, Matthew C., Garcia, Anthony D., Petti, Alessia, Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Lam, Kevin ORCID: 0000-0003-1481-9212 (2020) Organic electrosynthesis: From academia to industry. Reaction Chemistry & Engineering, 5 (6). pp. 977-990. ISSN 2058-9883 (Online) (doi:https://doi.org/10.1039/D0RE00064G)

Heterocyclic Chemistry, Prins reaction, aza-Prins reaction

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2017) The Asymmetric Aza-Prins Reaction presented at the 26th International Society of Heterocyclic Chemistry Congress, Regensburg, Germany 5-8 September 2017. In: 26th International Society of Heterocyclic Chemistry Congress, 5-8 September 2017, Regensburg, Germany. (Unpublished)

Heterocyclic chemistry palladium catalysis aminocarbonylation Benzimidazoimidazoles

Veltri, Lucia, Giofrè, Salvatore V., Devo, Perry, Romeo, Roberto, Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Gabriele, Bartolo (2018) A palladium iodide-catalyzed oxidative aminocarbonylation–heterocyclization approach to functionalized benzimidazoimidazoles. Journal of Organic Chemistry, 83. pp. 1680-1685. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/acs.joc.7b03167)

Heterocyclic chemistry, Aza-Prins reaction, Prins reaction

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2017) The Asymmeteric Aza-Prins and related reactions - presented at the 23rd Royal Society of Chemistry Grasmere Heterocyclic Chemistry Symposium. In: 23rd Lakeland Symposium on Heterocyclic Chemistry, Grasmere 2017, 4 - 8 May 2017, Grasmere, Ambleside. (Unpublished)

Heterocyclic chemistry; Spiroketals; Prins reaction

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2016) Photochemical and electrochemical methods for the synthesis of spiroketals. In: Royal Society of Chemistry/SCI Meeting on Synthesis in the Agrisciences, 22nd February 2016, Royal Society of Chemistry, Burlington House, London. (Unpublished)

Heterocyclic chemistry; Synthesis; Neglected diseases; Mesothelioma

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2016) Heterocycles and Neglected Diseases. In: Invited lecture, 13th December 2016, Nottingham Trent University. (Unpublished)

Lecture; Heterocyclic chemistry; Mesothelioma

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2017) Heterocycles and Neglected Diseases. In: Invited lecture, 6th February 2017, Keele University. (Unpublished)

Lewis acid, aza-Prins reaction, piperidines, pyrrolidines

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Guesné, Sebastien J.J., Parker, Robert J., Skidmore, John, Stephenson, Richard A. and Hursthouse, Mike B. (2010) A detailed investigation of the aza-Prins reaction. Organic & Biomolecular Chemistry, 8 (5). pp. 1064-1080. ISSN 1477-0520 (Print), 1477-0539 (Online) (doi:https://doi.org/10.1039/B915797B)

Medicinal chemistry; Heterocyclic chemistry; Mesothelioma

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2016) Novel heterocycles and medicinal chemistry of mesothelioma. In: 13th International Conference of the International Mesothelioma Interest Group, 1st - 4th May 2016, Birmingham. (Unpublished)

Organic Chemistry, Total synthesis, Prins reaction

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2014) Invited Lecture at the XVI National Organic Symposium Trust (NOST) Meeting. In: National Organic Symposium Trust (NOST) XVI Organic Chemistry Conference, 4-7 April 2014, Agra, India.

Organic chemistry total synthesis mesothelioma

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2015) Invited Lecture at the 2015 Florida Heterocyclic Chemistry Conference (FLOHET). In: 16th Florida Heterocyclic & Synthetic Conference 2015, 1-4 April 2015, University of Florida, Gainesville, USA. (Unpublished)

Prins reaction, aldehydes, indium trichloride

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Guesné, Sebastien J.J., Hursthouse, Michael B. and Coles, Simon J. (2003) [Letter] The aza-silyl-prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines. Synlett (11). pp. 1740-1742. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:https://doi.org/10.1055/s-2003-41434)

Prins reaction, silyl-Prins reaction, MukaiyamaeAldolesilyl-Prins reaction, Pyran, Dihydropyran, fluorinated pyran, Lewis acid, Civet

Chio, Freda K., Warne, Julie, Gough, Damien, Penny, Mark, Green, Sasa, Coles, Simon J., Hursthouse, Mike B., Jones, Peter, Hassall, Lorraine, McGuire, Thomas M. and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2011) On the choice of Lewis acids for the Prins reaction; two total syntheses of (±)-Civet. Tetrahedron, 67 (27-28). pp. 5107-5124. ISSN 0040-4020 (doi:https://doi.org/10.1016/j.tet.2011.05.019)

Silyl-Prins reaction, Aza-silyl-Prins reaction, 6-CF3-substituted dihydropyrans, 6-CF3-substituted tetrahydropyridines, Pipecolic acid derivatives

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Parker, Robert J. and Skidmore, John (2007) Rapid access to CF3 -containing heterocycles. Tetrahedron Letters, 49 (5). pp. 827-831. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2007.11.178)

aldehydes, Lewis acid, dihydropyrans, Prins and silyl-Prins reactions

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Martinović, Saša (2002) The silyl–Prins reaction: a novel method for the synthesis of dihydropyrans. Tetrahedron Letters, 43 (39). pp. 7055-7057. ISSN 0040-4039 (doi:https://doi.org/10.1016/S0040-4039(02)01558-7)

aza-Prins reaction, Lewis acid, piperidine, heterocyclic chemistry, Prins reaction, natural product

Cuprova, Lenka and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2019) Cascade aza-Prins reactions. Advances in Heterocyclic Chemistry. Academic Press, pp. 251-278. (doi:https://doi.org/10.1016/bs.aihch.2019.10.006)

aza-Prins reaction; aza-silyl-Prins reaction; Lewis acid; cascade cyclisation; aza-bicycle

Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2015) Synthesis of azabicycles via cascade aza-Prins reactions: accessing the indolizidine and quinolizidine cores. Journal of Organic Chemistry, 80 (20). pp. 9868-9880. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/acs.joc.5b01301)

donor-cyclopropane, silylmethylcyclopropane, silicon-stabilised carbocation, β-effect, tetrahydrofuran, Lewis acid promoted reaction

Dunn, Jonathan and Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2015) Synthesis and reactions of donor cyclopropanes: efficient routes to cis- and trans-tetrahydrofurans. Tetrahedron, 71 (39). pp. 7386-7414. ISSN 0040-4020 (doi:https://doi.org/10.1016/j.tet.2015.05.007)

electrosynthesis, radicals, oxycarbonyl, electrochemistry, organic chemistry

Petti, Alessia, Leech, Matthew C., Garcia, Anthony D., Goodall, Iain C.A., Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Lam, Kevin ORCID: 0000-0003-1481-9212 (2019) Economical, green, and safe route towards substituted lactones by anodic generation of oxycarbonyl radicals. Angewandte Chemie International Edition, 58 (45). pp. 16115-16118. ISSN 1433-7851 (Print), 1521-3773 (Online) (doi:https://doi.org/10.1002/anie.201909922)

fluorinated heterocycles, fluorine, Lewis acid, Prins cyclisation

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Pivnevi, Levan, Penny, Mark J., Martinović, Săsa, Iley, James N. and Stephenson, Peter T. (2006) Monofluorinated di- and tetrahydropyrans via Prins-type cyclisations. Chemical Communications, 29. pp. 3134-3136. ISSN 1359-7345 (Print), 1364-548X (Online) (doi:https://doi.org/10.1039/b606121d)

fluorous, fluorous biphasic catalysis, fluorous synthesis, liquid–liquid extraction, solid–liquid extraction

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Kimberley, Meriel R. (2002) Fluorous phase chemistry: a new industrial technology. Journal of Fluorine Chemistry, 118 (1-2). pp. 3-17. ISSN 0022-1139 (doi:https://doi.org/10.1016/S0022-1139(02)00202-6)

fluorous-TEMPO, fluorous solid-phase extraction, ESR spectra, oxidation reaction, radical spin trap

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Jones, Peter, Penny, Mark J. and Rigby, Stephen E. (2009) Light-fluorous TEMPO: reagent, spin trap and stable free radical. Tetrahedron, 65 (27). pp. 5271-5277. ISSN 0040-4020 (doi:https://doi.org/10.1016/j.tet.2009.04.078)

fluorous-TEMPO, fluorous solid-phase extraction, oxidation reaction

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Penny, Mark J. and Jones, Peter (2008) Novel light-fluorous TEMPO reagents and their application in oxidation reactions. Tetrahedron Letters, 49 (49). pp. 6955-6958. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2008.09.092)

green chemistry, electrosynthesis, MOM ether, flow chemistry, flow electrochemistry, 3D printing

van Melis, Carlo G. W., Penny, Matthew R., Garcia, Anthony D., Petti, Alessia, Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Hilton, Stephen T. and Lam, Kevin ORCID: 0000-0003-1481-9212 (2019) Supporting‐electrolyte‐free electrochemical methoxymethylation of alcohols using a 3D‐printed electrosynthesis continuous flow cell system. ChemElectrochem, 6 (16). pp. 4144-4148. ISSN 2196-0216 (Print), 2196-0216 (Online) (doi:https://doi.org/10.1002/celc.201900815)

heterocyclic chemistry, piperidines, aza-Prins reaction

Mittapalli, Ramana R., Guesné, Sebastien J.J., Parker, Robert J., Klooster, Wim, T., Coles, Simon, J., Skidmore, John and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2018) The asymmetric aza-silyl-prins reaction: Synthesis of enantiopure piperidines. Organic Letters, 21 (2). pp. 350-355. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:https://doi.org/10.1021/acs.orglett.8b03283)

hydrogermylation, hydrogermylation of alkenes, hydrogermylation of alkynes, hydroplumbation, hydroplumbation of alkenes, hydroplumbation of alkynes, hydrosilylation, hydrosilylation of alkenes, hydrosilylation of alkynes, hydrostannylation, hydrostannylation of alkenes, hydrostannylation of alkynes

Dobbs, A.P. ORCID: 0000-0002-7241-7118 and Chio, F.K.I. (2014) Hydrometallation Group 4 (Si, Sn, Ge, and Pb). In: Molander, Gary A. and Knochel, Paul, (eds.) Comprehensive Organic Synthesis II. Elsevier Ltd., Oxford, UK, pp. 964-998. ISBN 978-0-08-097743-0 (doi:https://doi.org/10.1016/B978-0-08-097742-3.00827-2)

indium trichloride, Prins reaction, silyl-Prins reaction

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Guesné, Sebastien J. J., Martinović, Saša, Coles, Simon J. and Hursthouse, Michael B. (2003) A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles. The Journal of Organic Chemistry, 68 (20). pp. 7880-7883. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo034981k)

organic chemistry, organic synthesis, heterocyclic chemistry, piperidines, pipecolic acid

Mittapalli, Ramana Reddy, Coles, Simon J., Klooster, Wim T. and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2021) A stereoselective aza-prins reaction: rapid access to enantiopure piperidines and pipecolic acids. Journal of Organic Chemistry, 86 (3). pp. 2076-2089. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/acs.joc.0c01897)

orthoesters, anodic oxidation, electrochemistry, electrosynthesis

Garcia, Anthony D., Leech, Matthew C., Petti, Alessia, Denis, Camille, Goodall, Iain C. A., Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Lam, Kevin ORCID: 0000-0003-1481-9212 (2020) Anodic oxidation of dithiane carboxylic acids: a rapid and mild 2 way to access functionalized orthoesters. Organic Letters, 22 (10). pp. 4000-4005. ISSN 1523-7060 (Print), 1523-7052 (Online) (doi:https://doi.org/10.1021/acs.orglett.0c01324)

radials, electrosynthesis, electrochemistry, isocyanate

Petti, Alessia, Fagnan, Corentin, van Melis, Carlo G. W., Tanbouza, Nour, Garcia, Anthony D., Mastrodonato, Andrea, Leech, Matthew C., Goodall, Iain C. A., Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Ollevier, Thierry and Lam, Kevin ORCID: 0000-0003-1481-9212 (2021) Supporting-electrolyte-free anodic oxidation of oxamic acids into isocyanates: an expedient way to access ureas, carbamates, and thiocarbamates. Organic Process Research & Development, 25 (12). pp. 2614-2621. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/acs.oprd.1c00112)

silicon-based tethers, Pauson-Khand reaction

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Miller, Ian J. and Martinović, Saša (2007) The use of silicon-based tethers for the Pauson-Khand reaction. Beilstein Journal of Organic Chemistry, 3 (21). pp. 1-11. ISSN 1860-5397 (Print), 1860-5397 (Online) (doi:https://doi.org/10.1186/1860-5397-3-21)

silylmethylcyclopropane, donor cyclopropane, 2,5-Disubstituted tetrahydrofuran

Dunn, Jonathan, Motevalli, Majid and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2011) Donor cyclopropanes in synthesis: utilising silylmethylcyclopropanes to prepare 2,5-disubstituted tetrahydrofurans. Tetrahedron Letters, 52 (51). pp. 6974-6977. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2011.10.091)

silylmethylcyclopropane, donor cyclopropane, 2,5-Disubstituted tetrahydrofuran, Flemming oxidation

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Dunn, Jonathan (2012) The synthesis and development of 2,5-disubstituted tetrahydrofurans as potential scaffolds for diversity-oriented synthesis. Tetrahedron Letters, 53 (19). pp. 2392-2395. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2012.02.100)

total synthesis, irciniasulfonic acid, total synthesis, multidrug resistance modulator

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Venturelli, Alberto, Parker, Robert J. and Butler, Laura A. (2005) [Letter] First total synthesis of the irciniasulfonic acids. Synlett (4). pp. 652-654. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:https://doi.org/10.1055/s-2005-862387)