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Cascade aza-Prins reactions

Cascade aza-Prins reactions

Cuprova, Lenka and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2019) Cascade aza-Prins reactions. Advances in Heterocyclic Chemistry. Academic Press, pp. 251-278. (doi:https://doi.org/10.1016/bs.aihch.2019.10.006)

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Abstract

Saturated nitrogen-containing heterocycles are the basis of a plethora of natural products, including alkaloids and aza-sugars, and a recent survey also demonstrated that the piperidine ring is the most abundant nitrogen-containing heterocycle in FDA-approved pharmaceutically active and commercially available drugs, being found in 72 drugs. The aza-Prins and related reactions have emerged as a rapid and highly efficient method for the preparation of 6-membered nitrogen-containing heterocycles. This chapter reviews recent developments in the aza-Prins reaction, particularly focussing on reports since 2000.

Item Type: Book Section
Additional Information: Published in Advances in Heterocyclic Chemistry, ISSN 0065-2725.
Uncontrolled Keywords: aza-Prins reaction, Lewis acid, piperidine, heterocyclic chemistry, Prins reaction, natural product
Subjects: Q Science > QD Chemistry
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > School of Science (SCI)
Last Modified: 21 Oct 2020 22:31
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
Selected for REF2021: None
URI: http://gala.gre.ac.uk/id/eprint/26537

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