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Rapid access to CF3 -containing heterocycles

Rapid access to CF3 -containing heterocycles

Dobbs, Adrian P. ORCID: 0000-0002-7241-7118, Parker, Robert J. and Skidmore, John (2007) Rapid access to CF3 -containing heterocycles. Tetrahedron Letters, 49 (5). pp. 827-831. ISSN 0040-4039 (doi:

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The silyl-Prins and aza-silyl-Prins reactions have been employed for the preparation of 6-CF3-substituted dihydropyrans and 6-CF3-substituted tetrahydropyridines. The product heterocycles have been further elaborated to a number of products, including CF3-substituted pipecolates and hydroxylated pyrans and piperidines.

Item Type: Article
Uncontrolled Keywords: Silyl-Prins reaction, Aza-silyl-Prins reaction, 6-CF3-substituted dihydropyrans, 6-CF3-substituted tetrahydropyridines, Pipecolic acid derivatives
Subjects: Q Science > QD Chemistry
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science > School of Science (SCI)
Related URLs:
Last Modified: 21 Oct 2020 22:31

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