Purchase, Susan E., Garcia-Prats, Anthony J., De Koker, Petra, Draper, Heather R., Osman, Muhammad ORCID: 0000-0003-3818-9729, Seddon, James A., Schaaf, H. Simon and Hesseling, Anneke C. (2019) Acceptability of a novel levofloxacin dispersible tablet formulation in young children exposed to multidrug-resistant tuberculosis. Pediatric Infectious Disease Journal, 38 (6). pp. 608-610. ISSN 0891-3668 (Print), 1532-0987 (Online) (doi:https://doi.org/10.1097/INF.0000000000002268)

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Abstract

Levofloxacin is used for the treatment and prevention of multidrug-resistant tuberculosis in children, but current adult formulations are poorly palatable. A questionnaire administered to caregivers of 27 children taking a novel 100 mg dispersible taste-masked levofloxacin tablet found the new formulation to be more palatable (69%) and easier to prepare (81%) than the adult formulation. This formulation may assist children to better adhere to anti-tuberculous therapy.

Item Type:	Article
Uncontrolled Keywords:	drug-resistant tuberculosis; TB prevention; acceptability
Subjects:	Q Science > QR Microbiology > QR355 Virology R Medicine > RJ Pediatrics
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified:	24 Mar 2022 10:24
URI:	http://gala.gre.ac.uk/id/eprint/35558

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