Items where Faculty / School / Research Centre / Research Groups is "Medway Centre for Pharmaceutical Science"

University Structure (19)
- Faculty of Engineering & Science (19)
  - Medway Centre for Pharmaceutical Science (19)
    - Pharmaceutical and Medicinal Science Research Group (13)

Group by: Date | Creators | Item Type | Uncontrolled Keywords | No Grouping

%HIA absorption aminopropyl column batch sulphoalkylation reaction bile salt biomolecules biosurfactant carriers for protein drug delivery Colloid microgel Continuous flow continuous flow conditions Continuous tank reactor synthesis copper ligand design C−H activation catalysis radical DFT EPR propargylamines Cyclodextrin Cyclodextrins Differential scanning Calorimetry Diffuse reflectance visible spectroscopy Elastomer Flocculation flow-through cells Flux haemoglobin HIA Hot-melt extrusion human intestinal absorption hydrogels Hydrogenation Hydrophobicity In-line monitoring Indomethacin Isophorone lipophilicity Mesoporous silica particles micellar liquid chromatography MLC Molecular solutions multiple linear regression myristic acid NaDC Near infrared spectroscopy Oligomer oral delivery PDMS permeation pharmacokinetics Plasma Pmw Polymorphic transformation Powder X-ray diffraction Process analytical technology protein immobilisation Raman mapping Reflectance Silicone sodium deoxycholate static diffusion cells Structure elucidation Sulfanilamide Sulphoalkyl ether-β-cyclodextrin Sulphobutylether β-cyclodextrins supercritical CO2 Tebbe reagent Total synthesis Transmission γ-globulin release

Number of items at this level: 70.

%HIA

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

absorption

aminopropyl column

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2019) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomedical Chromatography, 33 (7):e4515. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4515)

batch sulphoalkylation reaction

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

bile salt

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2018) Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption. Biomedical Chromatography, 32 (12):e4351. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4351)

biomolecules

Trivedi, Vivek, Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2019) Myristic acid coated protein immobilised mesoporous silica particles as pH induced oral delivery system for the delivery of biomolecules. Pharmaceuticals, 12 (4):153. ISSN 1424-8247 (doi:https://doi.org/10.3390/ph12040153)

biosurfactant

carriers for protein drug delivery

Ajiboye, Adejumoke Lara, Trivedi, Vivek and Mitchell, John ORCID: 0000-0003-2945-3292 (2020) Mesoporous silica particles as potential carriers for protein drug delivery: protein immobilisation and the effect of displacer on γ-globulin release. Drug Development and Industrial Pharmacy, Drug Development and Industrial Pharmacy, 46 (4). pp. 576-586. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.1080/03639045.2020.1742141)

Colloid microgel

Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2016) Colloidal microgels - untapped potential? Journal of Nanomedicine and Nanotechnology, 7 (4). pp. 1-2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000e142)

Continuous flow

Professor John Mitchell (2016) US20160024229A1 Cyclodextrin. US20160024229 A1.

continuous flow conditions

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

Continuous tank reactor synthesis

Mitchell, John ORCID: 0000-0003-2945-3292, Wicks, Stephen, Trivedi, Vivek ORCID: 0000-0001-9304-9214, Waters, Laura and Ehiwe, Tammy (2015) Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins. International Journal of Pharmaceutics, 495 (2). pp. 862-868. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.039)

copper ligand design C−H activation catalysis radical DFT EPR propargylamines

Devonport, Jack, Sully, Lauren, Boudalis, Athanassios K., Hassell-Hart, Storm, Leech, Matthew C., Lam, Kevin ORCID: 0000-0003-1481-9212, Abdul-Sada, Alaa, Tizzard, Graham J., Coles, Simon J., Spencer Evans, John, Vargas, Alfredo and Kostaki, George E. (2021) Room temperature Cu(II) radical-triggered Alkyne C−H activation. Journal of the American Chemical Society AU. ISSN 2691-3704 (Print), 2691-3704 (Online) (doi:https://doi.org/10.1021/jacsau.1c00310)

Cyclodextrin

Professor John Mitchell (2016) US20160024229A1 Cyclodextrin. US20160024229 A1.

Cyclodextrins

Differential scanning Calorimetry

Ehiwe, Tracy O., Alexander, Bruce D, Mitchell, John C. ORCID: 0000-0003-2945-3292, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Waters, Laura J. (2016) Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy. Journal of Pharmaceutical Analysis, 6 (3). ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2015.12.002)

Diffuse reflectance visible spectroscopy

Elastomer

Minicone, Fabrizio, Attrill, Robin, Hodgson, Michael, Wheelhouse, Katherine and Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2018) First total synthesis and structural confirmation of C13-Butylrubber Oligomers. European Journal of Organic Chemistry, 2018 (25). pp. 3271-3275. ISSN 1434-193X (Print), 1099-0690 (Online) (doi:https://doi.org/10.1002/ejoc.201800937)

Flocculation

flow-through cells

Flux

Waters, Laura J., Finch, Catherine V., Bhuiyan, A.K.M. Mehedi H., Hemming, Karl and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Effect of plasma surface treatment of poly (dimethylsiloxane) on the permeation of pharmaceutical compounds. Journal of Pharmaceutical Analysis, 7 (5). pp. 338-342. ISSN 2095-1779 (doi:https://doi.org/10.1016/j.jpha.2017.05.003)

haemoglobin

HIA

Hot-melt extrusion

Islam, Muhammad T., Scoutaris, Nikolaos, Maniruzzaman, Mohammed, Moradiya, Hiren G., Halsey, Sheelagh, Bradley, Michael, Chowdhry, Babur, Snowden, Martin ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2015) Implementation of transmission NIR as a PAT tool for monitoring drug transformation during HME processing. European Journal of Pharmaceutics and Biopharmaceutics, 96. pp. 106-116. ISSN 0939-6411 (Print), 1873-3441 (Online) (doi:https://doi.org/10.1016/j.ejpb.2015.06.021)

human intestinal absorption

hydrogels

Hydrogenation

Hydrophobicity

In-line monitoring

Indomethacin

Isophorone

lipophilicity

Mesoporous silica particles

micellar liquid chromatography

MLC

Molecular solutions

multiple linear regression

myristic acid

NaDC

Near infrared spectroscopy

Oligomer

oral delivery

PDMS

permeation

pharmacokinetics

Plasma

Pmw

Polymorphic transformation

Powder X-ray diffraction

Process analytical technology

protein immobilisation

Raman mapping

Reflectance

Silicone

sodium deoxycholate

static diffusion cells

Structure elucidation

Sulfanilamide

Sulphoalkyl ether-β-cyclodextrin

Professor John Mitchell (2016) US20160024229A1 Cyclodextrin. US20160024229 A1.

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