Items where Author is "Ovsepian, Saak"

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AbetaPP addiction adjuvant therapy adult neurogenesis advanced biomaterials Alzheimer’s disease amyloid deposition animal models animal models of autism animal toxins autism spectrum disorders autoimmune response autoimmunity axonal degeneration biomarkers brain brain evolution bulbar and spinal ALS ChIP cholinergic neurons chronic pain cingulate gyrus circadian rhythms cognitive decline cognitive deficit contraception cortical expansion cortical thinning default mode networks dementia dendritic morphology dendritic spine differential diagnosis Differentiation dopamine dopamine transporter drug abuse Eker rats endocannabinoids endogenous polyamines enriched environment enteric nervous system epileptic seizures estradiol excitotoxicity exosome exosomes fluid biomarker fluid biomarkers fluorescent probes gender transition gene therapy GluN1 subunit glutamate release gluten hamartoma healthy ageing histone HLA hormone replacement therapy ICG immunoglobins intrinsic excitability Ion channels kynurenic acid long non-coding RNA major histocompatibility complex II menopause mental health methamphetamine methylation microbiome miRNA modafinil monocyte-derived dendritic cells motor neuron disease motor units mRNA mTOR signalling neoplasia neurodegeneration neurodegenerative disease neurofilament light chain neurogranin neuroplasticity neuroprotection neurosteroids nociception oestrogen open field test optical imaging p75 NTR PARTICLE perinatal affective disorder placenta plasticity polyamines postpartum depression pregnancy psd95 refractory epilepsy renal cell cancer sensory neurons SH-SY5Y skeletal and visceral muscles sleep and insomnia SOD1 mutation Super-resolution microscopy tau Tau protein TDP43 TINA transgender TrkB receptor TSC1 TSC2 tuberous sclerosis complex tumor drug resistance tumor microenvironment visualisation zinc

Number of items: 136.

AbetaPP

Riegerova, Petra, Brejcha, Jundrich, Bezdekova, Dagmar, Chum, Tomas, Masinova, Eva, Cermakova, Nikola, Ovsepian, Saak, Cebecauer, Marek and Stefl, Marek (2021) Expression and localization of AβPP in SH-SY5Y cells depends on differentiation state. Journal of Alzheimer's Disease, 82. pp. 485-491. ISSN 2542-4823 (Online) (doi:https://doi.org/10.3233/JAD-201409)

addiction

Vrajova, Monika, Slamberova, Romana, Hoschl, Cyril and Ovsepian, Saak (2021) Methamphetamine and sleep impairments: neurobehavioral correlates and molecular mechanisms. Sleep, 44 (6):zsab001. ISSN 0161-8105 (Print), 1550-9109 (Online) (doi:https://doi.org/10.1093/sleep/zsab001)

adjuvant therapy

Androvičová, Renáta, Pfaus, James G and Ovsepian, Saak (2021) Oestrogen pendulum in schizophrenia and Alzheimer's disease: review of therapeutic benefits and outstanding questions. Neuroscience Letters, 759:136038. pp. 1-8. ISSN 0304-3940 (Print), 0304-3940 (Online) (doi:https://doi.org/10.1016/j.neulet.2021.136038)

adult neurogenesis

Ovsepian, Saak and O'Leary, Valerie (2022) Adult neurogenesis in the gut, homeostatic autoimmunity and neurodegenerative disease biomarkers. Neuroscience, 10 (504). pp. 75-78. ISSN 0306-4522 (doi:https://doi.org/10.1016/j.neuroscience.2022.09.019)

advanced biomaterials

Ergen, Pinar Helin, Shorter, Susan, Ntizachristos, Vasilis and Ovsepian, Saak (2023) Neurotoxin-derived optical probes for biological and medical imaging. Molecular Imaging and Biology, 25. pp. 799-814. ISSN 1536-1632 (Print), 1860-2002 (Online) (doi:https://doi.org/10.1007/s11307-023-01838-1)

Alzheimer’s disease

Ovsepian, Saak, O'Leary, Valerie, Hoschl, Cyril and Zaborszky, Laszlo (2021) Integrated phylogeny of the human brain and pathobiology of Alzheimer's disease: a unifying hypothesis. Neuroscience Letters, 11 (755):135895. pp. 1-9. ISSN 0304-3940 (Print), 0304-3940 (Online) (doi:https://doi.org/10.1016/j.neulet.2021.135895)

amyloid deposition

animal models

animal models of autism

Granak, Simon, Tuckova, Klara, Kutna, Viera, Vijtechova, Iveta, Bajkova, Laura, Petrasek, Tomas and Ovsepian, Saak (2022) Developmental effects of the impact of constitutive mTORC1 hyperactivity and environmental enrichment on structural synaptic plasticity and behaviour in a rat model of autism spectrum disorder. European Journal of Neuroscience, 57 (1). pp. 17-31. ISSN 0953-816X (Print), 1460-9568 (Online) (doi:https://doi.org/10.1111/ejn.15864)

animal toxins

autism spectrum disorders

Kutna, Viera, O'Leary, Valerie, Newman, Ehren, Hoschl, Cyril and Ovsepian, Saak (2021) Revisiting brain tuberous sclerosis complex in rat and human: shared molecular and cellular pathology leads to distinct neurophysiological and behavioural phenotypes. Neurotherapeutics - The Journal of the American Society for Experimental Neurotherapeutics, 18 (2). pp. 845-858. ISSN 1933-7213 (Print), 1878-7479 (Online) (doi:https://doi.org/10.1007/s13311-020-01000-7)

autoimmune response

Jorratt, Pascal, Hoschl, Cyril and Ovsepian, Saak (2021) Endogenous antagonists of N-Methyl-D-Aspartate receptor in schizophrenia. Alzheimers and Dementia, 17 (5). pp. 888-905. ISSN 1552-5279 (Print), 1552-5279 (Online) (doi:https://doi.org/10.1002/alz.12244)

autoimmunity

Hudec, Michael, Jurícková, Iva, Riegerová, Kamila, Ovsepian, Saak, Cerná, Marie and O’Leary, Valerie (2022) Enhanced extracellular transfer of HLA-DQ activates CD3+ lymphocytes towards compromised Treg induction in celiac disease. International Journal of Molecular Sciences, 23 (11):6102. ISSN 1661-6596 (doi:https://doi.org/10.3390/ijms23116102)

Kocurova, Gabriela, Ricny, Jan and Ovsepian, Saak (2022) Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases. Theranostics, 12 (7). pp. 3045-3056. ISSN 1838-7640 (Online) (doi:https://doi.org/10.7150/thno.72126)

axonal degeneration

Negi, Deepika, Granak, Simon, Shorter, Susan, O’Leary, Valerie B., Rekto, Ivan and Ovsepian, Saak (2023) Molecular biomarkers of neuronal injury in epilepsy shared with neurodegenerative diseases. Neurotherapeutics. ISSN 1933-7213 (Print), 1878-7479 (Online) (doi:https://doi.org/10.1007/s13311-023-01355-7)

biomarkers

brain

Ovsepian, Saak, O'Leary, Valerie and Hoschl, Cyril (2021) Mainstream psychiatry reinstates therapeutic ventures of the remote past. Drug Discovery Today, 26 (3). pp. 845-851. ISSN 1359-6446 (Print), 1359-6446 (Online) (doi:https://doi.org/10.1016/j.drudis.2021.01.011)

brain evolution

bulbar and spinal ALS

Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:https://doi.org/10.1007/s00429-023-02728-6)

ChIP

Juříčková, Iva, Hudec, Michael, Votava, Felix, Vosáhlo, Jan, Ovsepian, Saak, Černá, Marie and O'Leary, Valerie (2022) The immunological epigenetic landscape of the human life trajectory. Biomedicines, 10 (11):2894. ISSN 2227-9059 (Online) (doi:https://doi.org/10.3390/biomedicines10112894)

cholinergic neurons

chronic pain

Ovsepian, Saak and Waxman, Stephen (2023) Gene therapy for chronic pain: emerging opportunities in target-rich peripheral nociceptors. Nature Review Neuroscience, 12 (1):1. pp. 252-265. ISSN 1471-003X (Print), 1471-0048 (Online) (doi:https://doi.org/10.1038/s41583-022-00673-7)

cingulate gyrus

circadian rhythms

cognitive decline

Zhang, Grace, Devo, Perry ORCID: 0000-0003-1487-8896 , O'Leary, Valerie B. ORCID: 0000-0003-1171-9830 and Ovsepian, Saak ORCID: 0000-0002-9522-4159 (2023) Ageing perspective on cognitive outcomes from auxiliary reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:https://doi.org/10.1016/j.heliyon.2023.e19050)

Zhang, Grace, Devo, Perry, O'Leary, Valerie and Ovsepian, Saak (2023) Ageing perspective on cognitive outcomes from reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:https://doi.org/10.1016/j.heliyon.2023.e19050)

cognitive deficit

contraception

cortical expansion

cortical thinning

Jorratt, Pascal, Ricny, Jan, Leibold, Christian and Ovsepian, Saak (2022) Endogenous modulators of NMDA receptor control dendritic field expansion of cortical neurons. Molecular Neurobiology. ISSN 0893-7648 (Print), 1559-1182 (Online) (doi:https://doi.org/10.1007/s12035-022-03147-0)

default mode networks

dementia

dendritic morphology

dendritic spine

differential diagnosis

Differentiation

dopamine

dopamine transporter

drug abuse

Eker rats

endocannabinoids

endogenous polyamines

enriched environment

enteric nervous system

epileptic seizures

estradiol

Singh, Saumya, Fereshetyan, Katarine, Shorter, Susan, Paliokha, Ruslan, Dremencov, Eliyahu, Yenkoyan, Konstantin and Ovsepian, Saak (2022) Brain-derived neurotrophic factor (BDNF) in perinatal depression: side show or pivotal factor? Drug Discovery Today, 28 (2):103467. pp. 1-7. ISSN 1359-6446 (doi:https://doi.org/10.1016/j.drudis.2022.103467)

excitotoxicity

exosome

exosomes

Boussios, Stergios, Devo, Perry, Rassy, Elie and Ovsepian, Saak (2023) Exosomes in the diagnosis and treatment of renal cell cancer. International Journal of Molecular Sciences, 24 (18):14356. pp. 1-23. ISSN 1661-6596 (Print), 1422-0067 (Online) (doi:https://doi.org/10.3390/ijms241814356)

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