Yusof, Ya’Akob, Patar, Mohd Nor Azmi Ab, Patar, Azim, Le, Chi Hieu ORCID: https://orcid.org/0000-0002-5168-2297 and Mahmud, Jamaluddin (2025) Evaluating the relationship between locomotion speed and gait patterns in SCI-injured rats. In: 2024 IEEE 22nd Student Conference on Research and Development (SCOReD), December 19th - 20th, 2024, Selangor, Malaysia. IEEE Xplore . Institute of Electrical and Electronics Engineers (IEEE), Piscataway, New Jersey, pp. 328-332. ISBN 979-8331510077; 979-8331510084 ISSN 2643-2439 (Print), 2643-2447 (Online) (doi:10.1109/SCOReD64708.2024.10872642)

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Abstract

Analyzing changes in gait patterns is a common method for evaluating injury severity and progression during rehabilitation, including in rats with contusion spinal cord injury (SCI). This study aims to examine the correlation between gait parameters and locomotor speed in rats with contusion SCI using a newly developed walkway system. Thirteen female Wistar rats (7 uninjured and 6 injured) were selected for this experiment. All of them walked through a walkway and a camera below the walkway recorded their motion. Their gait and speed data were analyzed to provide insights into post-injury locomotion. The system output shows that injured rats exhibit slower speeds, shorter stride lengths, and wider stance widths compared to the uninjured, proving that their gait and speed of the injured rats were altered due to the injury. Additionally, Pearson correlation analysis revealed a strong positive correlation (r=0.746) between speed and stride length for uninjured rats, while injured rats showed a moderate correlation (r =0.471). Furthermore, stance width demonstrated a moderate negative correlation with speed for both uninjured (r=−0.503) and injured rats (r=−0.488). These relationships, although not statistically significant due to sample size limitations, suggest meaningful trends and provide a foundation for future research where the relationship between the speed and gait parameters can be used to further justify the condition of SCI in rats. Future studies with larger sample sizes might strengthen these findings and clarify the role of speed-related gait changes in SCI rehabilitation process.

Item Type:	Conference Proceedings
Title of Proceedings:	2024 IEEE 22nd Student Conference on Research and Development (SCOReD), December 19th - 20th, 2024, Selangor, Malaysia
Additional Information:	“© 2025 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.” - MP
Uncontrolled Keywords:	correlation, surgery, rats, market research, solids, cameras, spinal cord injury, injuries, research and development, gait parameters;locomotion speed;rat;spinal cord injury;walkway system
Subjects:	Q Science > Q Science (General) T Technology > T Technology (General)
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > School of Engineering (ENG)
Last Modified:	26 Feb 2025 10:43
URI:	http://gala.gre.ac.uk/id/eprint/49862

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