Tabriz, Atabak Ghanizadeh, Kuofie, Hannah, Scoble, James, Boulton, Sam and Douroumis, Dionysios (Dennis) ORCID: 0000-0002-3782-0091 (2023) Selective laser sintering for printing pharmaceutical dosage forms. Journal of Drug Delivery Science and Technology, 86:104699. pp. 1-13. ISSN 1773-2247 (Print), 2588-8943 (Online) (doi:https://doi.org/10.1016/j.jddst.2023.104699)

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Abstract

Three-dimensional (3D) printing has revolutionised the field of pharmaceutical manufacturing due to the unique capabilities to tailor the dosage forms properties and overcome constrains of conventional technologies. There is a plurality of 3D printing techniques that offer flexibility on the shape, geometry, active(s) dose and dissolution rates for improved patient treatment. Over the last few years selective laser sintering (SLS) has captured research interest for the development of innovative drug products. SLS possess technological features that can transform medicine manufacturing from one-size-fits-all to personalised dosage forms with improved clinical outcomes, patient acceptability, and adherence. Moreover, SLS has the capacity to pave the way for decentralised manufacturing and introduce new supply chain models with reduce complexity. In this review we present the technological features, manufacturing challenges, advantages and limitations of SLS for manufacturing medicines.

Item Type:	Article
Additional Information:	** Article version: AM ** From Elsevier via Jisc Publications Router ** History: accepted 20-06-2023; issued 21-06-2023. ** Licence for AM version of this article starting on 21-06-2023: http://creativecommons.org/licenses/by/4.0/
Uncontrolled Keywords:	selective laser sintering; 3D printing; manufacturing; personalised; medicines; decentralised; oral; polymers
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General) T Technology > T Technology (General)
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	http://creativecommons.org/licenses/by/4...
SWORD Depositor:	Users 6393 not found.
Last Modified:	20 May 2024 16:15
URI:	http://gala.gre.ac.uk/id/eprint/43515

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