Items where Author is "Everett, Jeremy"

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(HTS) 1. Metabolic phenotyping 2. Metabonomics 3. Metabolomics 4. Drug Discovery 5. Drug Development 6. Attrition 7. Target Discovery 8. Drug Efficacy 9. Drug Safety 10. Pharmacometabonomics 10th Anniversary IDDST Conference 2 2012 2nd Generation 3-butanediol 6-hydroxy-6-methyl-heptan-3-one Academic ageing allyl formate anti-aging anti-obesogenic antibiotic autophagy biofluids bioRxiv preprint server biosynthesis body weight C. elegans C. elegans worms C57BL/6J cardiovascular cells chemometrics chemotherapy China cholesterol cholesterol-lowering classification colorectal cancer diagnosis disease Diversity Drug development Drug discovery Drug manufacture drug metabolism Drug Metabolism and Disposition Drug patents emrstm1286 ethionine fermentation flavin monooxygenase FMO5 FMO5 KO galactosamine genetic knock-out genetic mutants genomics glucose gut microbiome HCT116 High Throughput Screening High Throughput Screening (HTS) HTS human dose humans hypertyrosinemia hypotaurine individualized medicine isoniazid KRAS Lead discovery Lead discovery efficiency liver longevity Magic Angle Spinning malic enzyme 1 medicine meeting highlights metabolic entropy metabolic phenotyping metabolic profiling metabolism metabolite Metabolite Identification metabolite identification carbon efficiency (MICE) metabolite identification efficiency (MIE) Metabolite Profiling metabolite topology metabolites metabolomics metabonomics Metabonomics etabolomics Metabonomics Pharmacometabonomics FMO5 Metabolite Identification Metabonomics Pharmacometabonomics Personalised Medicine metabotypes MICE microbes mixed cultures Molecular probes molecular redundancy molecular spectroscopic information Molecular structure mouse MRI MRS mutations Nanjing natural nematode NMR NMR (nuclear magnetic resonance) spectroscopy NMR spectroscopy Nuclear Magnetic Resonance Nuclear magnetic resonance (NMR) spectroscopy nuclear magnetic resonance spectroscopy Orthogonal-Partial Least Squares Pan-assay interference compounds (PAINS) Partial Least Squares pattern recognition personalised health care personalised healthcare personalised medicine Personalised or precision medicine personalized medicine pharmacogenomics pharmacometabolomics pharmacometabonomics Pharmacometabonomics Metabonomics phototherapy plasma plate based plate based diversity screening Plate-Based precision medicine precision personalised medicine prediction Prediction of PK predictive metabolomics predictive metabonomics prognosis rat Regulatory affairs Ro40 Rule of 40 rule of 40 (Ro40) safety Screening File spermidine stomach Subset surgery SW48 systems medicine taurine thioacetamide tMICE topological metabolite identification carbon efficiency (tMICE) topological metabolite identification nitrogen and carbon efficiency (tMINCE) toxicity tyrosine aminotransferase urine white adipose tissue

Number of items: 293.

(HTS)

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:10.1007/s11030-013-9438-x)

1. Metabolic phenotyping 2. Metabonomics 3. Metabolomics 4. Drug Discovery 5. Drug Development 6. Attrition 7. Target Discovery 8. Drug Efficacy 9. Drug Safety 10. Pharmacometabonomics

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2018) Applications of metabolic phenotyping in pharmaceutical research and development. In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.) The Handbook of Metabolic Phenotyping. Elsevier, pp. 407-448. ISBN 978-0128122938

10th Anniversary IDDST Conference

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:10.1517/17460441.2013.762353)

2

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

2012

2nd Generation

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Loesel, Jens, McLoughlin, David, Mills, James, Peakman, Marie-Claire, Sharp, Robert E., Williams, Christine and Zhu, Hongyao (2016) Plate-based diversity subset screening generation 2: An improved paradigm for high throughput screening of large compound files. Molecular Diversity, 20 (4). pp. 789-803. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:10.1007/s11030-016-9692-9)

3-butanediol

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

6-hydroxy-6-methyl-heptan-3-one

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:10.3389/fmolb.2018.00028)

Academic

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:10.1517/17460441.2015.1059816)

ageing

Said, Mohamed, Ferrara, Bill T. ORCID: https://orcid.org/0000-0002-2163-4032, Aprodu, Andrea, Cabreiro, Filipe, Thompson, Elinor P. ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy (2024) Transcriptional analysis of C. elegans fmos at different life stages and their roles in ageing. Molecular Genetics and Genomics, 299:113. ISSN 1617-4615 (Print), 1617-4623 (Online) (doi:10.1007/s00438-024-02201-x)

Said, Mohamed, Thompson, Elinor ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2021) Modulation of ageing by genetic knock-out, phototherapy and drugs in the C. elegans worm. In: Metabolism of Ageing, 06 - 08 Sep 2021, online. (Unpublished)

Said, Mohamed, Thompson, Elinor ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2019) Metabolic ageing in the C. elegans worm and modulation by genetic knock-out, phototherapy and drugs. In: UK C.elegans meeting, 16th September 2019, Imperial College London, Sir Alexander Fleming Building, Imperial College Rd, London, UK. (Unpublished)

allyl formate

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:10.1021/pr0601584)

anti-aging

Keohane, Patrick, Everett, Jeremy, Pereira, Rui, EVERETT, Jeremy, Blonquist, Traci and Mah, Eunice (2024) Supplementation of spermidine at 40 mg/day has minimal effects on circulating polyamines: an exploratory double-blind randomized controlled trial in older men. Nutrition Research, 132. ISSN 0271-5317 (Print), 1879-0739 (Online) (doi:10.1016/j.nutres.2024.09.012)

anti-obesogenic

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

antibiotic

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:10.3389/fphys.2022.859681)

autophagy

biofluids

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Lindon, John and Nicholson, Jeremy (2016) Pharmacometabonomics and predictive metabonomics: New tools for personalised medicine. In: Nicholson, Jeremy, Darzi, A, Lindon, John and Holmes, Elaine, (eds.) Metabolic Phenotyping in Personalized and Public Healthcare. Elsevier Science Publishing Co Inc, pp. 137-165. ISBN 9780128003442 (doi:10.1016/B978-0-12-800344-2.00006-9)

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

bioRxiv preprint server

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:10.1124/dmd.119.089995)

biosynthesis

body weight

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:10.1016/j.bcp.2015.05.013)

C. elegans

C. elegans worms

C57BL/6J

cardiovascular

cells

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:10.1007/s11306-020-01674-2)

chemometrics

chemotherapy

Nicholson, Jeremy K., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:10.1517/17425255.2012.646987)

China

cholesterol

cholesterol-lowering

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

classification

colorectal cancer

diagnosis

disease

Diversity

Drug development

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:10.1002/9780470034590.emrstm1389)

Drug discovery

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

Drug manufacture

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

drug metabolism

Drug Metabolism and Disposition

Drug patents

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

emrstm1286

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) NMR-based pharmacometabonomics: A new approach to personalised medicine. In: Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilaon, Ian, (eds.) NMR in Pharmaceutical Sciences. eMagRes books, 4 . John Wiley & Sons Ltd, Chichester, UK, pp. 359-372. ISBN 9780470034590

ethionine

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:10.1007/s00204-006-0136-7)

fermentation

Hakalehto, Elias, Laatkainen, Reino, Pesola, Jouni, Dahlquist, Erik and Everett, Jeremy (2024) Chapter 3. Mixed strain fermentation and metabolomics for solving issues of bioproduction. In: Hakalehto, Elias, (ed.) Mixed Cultures in Industrial Bioprocesses. Advances in Biochemical Engineering/Biotechnology (ABE), 189 . Springer Cham, Berlin; Heidelberg, pp. 1-19. ISBN 978-3031735257; 978-3031735288; 978-3031735264 (doi:10.1007/10_2024_266)

flavin monooxygenase

FMO5

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) Pharmacogenomics and pharmacometabonomics for personalised medicine. In: FOCUS 2015: National Meeting of the Association for Clinical Biochemistry & Laboratory Medicine, 8-11 June 2015, Cardiff, Wales.

FMO5 KO

galactosamine

genetic knock-out

genetic mutants

genomics

glucose

gut microbiome

HCT116

High Throughput Screening

High Throughput Screening (HTS)

Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P. (2012) Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. Journal of Chemical Information and Modeling, 52 (11). pp. 2937-2949. ISSN 1549-9596 (Print), 1549-960X (Online) (doi:10.1021/ci300372a)

HTS

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2013) New approaches to the design of large screening files for lead discovery. In: Lifescience R&D Big Data Leaders Forum, 3-5 Dec 2013, Basel, Switzerland.

human dose

humans

hypertyrosinemia

hypotaurine

individualized medicine

isoniazid

KRAS

Lead discovery

Lead discovery efficiency

liver

longevity

Magic Angle Spinning

malic enzyme 1

medicine

meeting highlights

metabolic entropy

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:10.1016/j.tips.2019.08.004)

metabolic phenotyping

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2019) Pharmacometabonomics: the prediction of drug effects using metabolic profiling. In: Barrett, James E., Page, Clive P. and Michel, Martin C., (eds.) Concepts and Principles of Pharmacology: 100 Years of the Handbook of Experimental Pharmacology. Handbook of Experimental Pharmacology, 260 . Springer, Cham, Switzerland, pp. 263-300. ISBN 978-3030353612 (doi:10.1007/164_2019_316)

metabolic profiling

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:10.1016/j.pnmrs.2017.04.003)

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:10.4155/ipk-2016-0010)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:10.3389/fphar.2016.00297)

Sanchon-Lopez, Beatriz and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2016) New methodology for known metabolite identification in metabonomics / metabolomics: topological metabolite identification carbon efficiency (tMICE). Journal of Proteome Research, 15 (9). pp. 3405-3419. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:10.1021/acs.jproteome.6b00631)

metabolism

metabolite

Metabolite Identification

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Sanchon Lopez, Beatriz (2016) New Approaches to NMR-Based Metabolite Identification. In: 12th Annual Conference of the Metabolomics Society, 27 June 2016 - 30 June 2016, Dublin, Eire.

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:10.1016/j.csbj.2016.02.005)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) From metabonomics to pharmacometabonomics: An NMR-based excursion from metabolite profiling to precision medicine. In: Invited Lecture at Institute of Food Research, 19 March 2015, Institute of Food Research, Norwich, UK.

metabolite identification carbon efficiency (MICE)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:10.1016/j.csbj.2015.01.002)

metabolite identification efficiency (MIE)

Metabolite Profiling

metabolite topology

metabolites

metabolomics

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:10.2217/PGS.15.20)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Loo, Ruey Leng and Pullen, Francis S. (2013) Pharmacometabonomics and personalized medicine. Annals of Clinical Biochemistry, 50 (6). pp. 523-545. ISSN 0004-5632 (Print), 1758-1001 (Online) (doi:10.1177/0004563213497929)

metabonomics

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2014) Pharmacometabonomics: An important new paradigm for precision medicine. In: Metabomeeting 2014, 10-12 Sep 2014, The Royal Institution, London, UK. (Unpublished)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2013) New approaches to personalised medicine via pharmacometabonomics. In: Lifescience R&D Big Data Leaders Forum, 3-5 Dec 2013, Basel, Switzerland.

Cunningham, Katharine, Claus, Sandrine P., Lindon, John C., Holmes, Elaine, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Nicholson, Jeremy K. and Coen, Muireann (2012) Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. Journal of Proteome Research, 11 (9). pp. 4630-4642. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:10.1021/pr300430u)

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2006) Metabolic applications in clinical pharmaceutical R&D. In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.) The Handbook of Metabonomics and Metabolomics. Elsevier, Amsterdam, The Netherlands, pp. 279-287. ISBN 9780444528414

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:10.1038/nature04648)

Metabonomics etabolomics

Metabonomics Pharmacometabonomics FMO5 Metabolite Identification

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) From metabonomics to pharmacometabonomics: Mice, men and microbiota. In: Neuviemes Journees Scientifiques du Reseau Francais de Metabolomique et Fluxomique, 9 -11 June 2015, Lille, France. (Unpublished)

Metabonomics Pharmacometabonomics Personalised Medicine

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2015) From metabonomics to pharmacometabonomics: Mice, men and m microbiota. In: University College London Spring Seminars, 25 February 2015, University College London, UK.

metabotypes

MICE

microbes

mixed cultures

Molecular probes

molecular redundancy

molecular spectroscopic information

Molecular structure

mouse

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

MRI

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

MRS

mutations

Nanjing

natural

nematode

NMR

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666

NMR (nuclear magnetic resonance) spectroscopy

NMR spectroscopy

Nuclear Magnetic Resonance

Nuclear magnetic resonance (NMR) spectroscopy

nuclear magnetic resonance spectroscopy

Orthogonal-Partial Least Squares

Pan-assay interference compounds (PAINS)

Partial Least Squares

pattern recognition

personalised health care

personalised healthcare

personalised medicine

Personalised or precision medicine

personalized medicine

pharmacogenomics

pharmacometabolomics

pharmacometabonomics

Pharmacometabonomics Metabonomics

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2014) Pharmacometabonomics: The ability to use pre-dose metabolite profiles to predict drug responses. In: EMBL Practical Course: Metabolomics Bioinformatics for Life Scientists, 17- 21 March, 2014, Hinxton Genome Campus, UK.

phototherapy

plasma

plate based

plate based diversity screening

Plate-Based

precision medicine

precision personalised medicine

prediction

Prediction of PK

predictive metabolomics

predictive metabonomics

prognosis

rat

Regulatory affairs

Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.) (2015) NMR in pharmaceutical sciences. eMagRes Books . Wiley. ISBN 9781118997666