Items where Greenwich Author is "Ovsepian, Saak"
260531/SVV/2020-2022: Multidisciplinary research of the regulation mechanisms
Juříčková, Iva, Hudec, Michael, Votava, Felix, Vosáhlo, Jan, Ovsepian, Saak, Černá, Marie and O'Leary, Valerie (2022) The immunological epigenetic landscape of the human life trajectory. Biomedicines, 10 (11):2894. ISSN 2227-9059 (Online) (doi:10.3390/biomedicines10112894)
Charles University (Program No. 260533/SVV/2022)
Kutna, Viera, O'Leary, Valerie Brid, Hoschl, Cyril and Ovsepian, Saak V. (2022) Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism Research, 15 (5). pp. 791-805. ISSN 1939-3792 (Print), 1939-3806 (Online) (doi:10.1002/aur.2688)
Charles University research program COOPERATIO (grant number 207036): the scientific project ‘Medical Diagnostics and Basic Medical Sciences’ (the field ‘Medical Genetics’)
Juříčková, Iva, Hudec, Michael, Votava, Felix, Vosáhlo, Jan, Ovsepian, Saak, Černá, Marie and O'Leary, Valerie (2022) The immunological epigenetic landscape of the human life trajectory. Biomedicines, 10 (11):2894. ISSN 2227-9059 (Online) (doi:10.3390/biomedicines10112894)
Charles University research program COOPERATIO: the scientific project “Medical Diagnostics and Basic Medical Sciences” (in the field “Medical Genetics”), grant number 207036
Pokorná, Markéta, Cern, Marie, Boussios, Stergios, Ovsepian, Saak V. and Bríd O’Leary, Valerie (2024) lncRNA biomarkers of glioblastoma multiforme. Biomedicines, 12:932. pp. 1-37. ISSN 2227-9059 (Online) (doi:10.3390/biomedicines12050932)
Pokorná, Markéta, Kútna, Viera, Ovsepian, Saak V., Matěj, Radoslav, Cerná, Marie and Brid O'Leary, Valerie (2024) Biomolecules to biomarkers? U87MG marker evaluation on the path towards glioblastoma multiforme pathogenesis. Pharmaceutics, 16 (1):123. pp. 1-16. ISSN 1999-4923 (Print), 12 January 2024 / Published: 18 January 2024 (Online) (doi:10.3390/pharmaceutics16010123)
Charles University, Third Faculty of Medicine Research
Zhang, Grace, Devo, Perry ORCID: https://orcid.org/0000-0003-1487-8896, O'Leary, Valerie B. ORCID: https://orcid.org/0000-0003-1171-9830 and Ovsepian, Saak ORCID: https://orcid.org/0000-0002-9522-4159 (2023) Ageing perspective on cognitive outcomes from auxiliary reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:10.1016/j.heliyon.2023.e19050)
Charles University, Third Faculty of Medicine Research Program COOPERATIO-207036
Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:10.1007/s00429-023-02728-6)
Zhang, Grace, Devo, Perry, O'Leary, Valerie and Ovsepian, Saak (2023) Ageing perspective on cognitive outcomes from reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:10.1016/j.heliyon.2023.e19050)
Ovsepian, Saak and O'Leary, Valerie (2022) Adult neurogenesis in the gut, homeostatic autoimmunity and neurodegenerative disease biomarkers. Neuroscience, 10 (504). pp. 75-78. ISSN 0306-4522 (doi:10.1016/j.neuroscience.2022.09.019)
Charles University, Third Faculty of Medicine, Prague, CZ
Hudec, Michael, Jurícková, Iva, Riegerová, Kamila, Ovsepian, Saak, Cerná, Marie and O’Leary, Valerie (2022) Enhanced extracellular transfer of HLA-DQ activates CD3+ lymphocytes towards compromised Treg induction in celiac disease. International Journal of Molecular Sciences, 23 (11):6102. ISSN 1661-6596 (doi:10.3390/ijms23116102)
Generalitat Valenciana (GVA: Prometeo/2018/041)
Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:10.1007/s00429-023-02728-6)
Impact Development Fund and Innovation Fund Award grants from the University of Greenwich
Devo, Perry, Cretu, Victoria, Radhakrishnan, Harsha, Hamilton-Pink, Darren, Boussios, Stergios and Ovsepian, Saak V. (2024) An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry. Journal of Neural Transmission. ISSN 0300-9564 (Print), 1435-1463 (Online) (doi:10.1007/s00702-024-02862-3)
Innovation Fund Award 2022 and Research Excellence Framework grant from the University of Greenwich
Ovsepian, Saak and O'Leary, Valerie (2022) Adult neurogenesis in the gut, homeostatic autoimmunity and neurodegenerative disease biomarkers. Neuroscience, 10 (504). pp. 75-78. ISSN 0306-4522 (doi:10.1016/j.neuroscience.2022.09.019)
Innovation Fund Award 2022 from the University of Greenwich
Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:10.1007/s00429-023-02728-6)
Zhang, Grace, Devo, Perry, O'Leary, Valerie and Ovsepian, Saak (2023) Ageing perspective on cognitive outcomes from reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:10.1016/j.heliyon.2023.e19050)
Ergen, Pinar Helin, Shorter, Susan, Ntizachristos, Vasilis and Ovsepian, Saak (2023) Neurotoxin-derived optical probes for biological and medical imaging. Molecular Imaging and Biology, 25. pp. 799-814. ISSN 1536-1632 (Print), 1860-2002 (Online) (doi:10.1007/s11307-023-01838-1)
Innovation Fund Award 2022 from the University of Greenwich; Charles University, Third Faculty of Medicine Research Program COOPERATIO-207036
Negi, Deepika, Granak, Simon, Shorter, Susan, O’Leary, Valerie B., Rekto, Ivan and Ovsepian, Saak (2023) Molecular biomarkers of neuronal injury in epilepsy shared with neurodegenerative diseases. Neurotherapeutics. ISSN 1933-7213 (Print), 1878-7479 (Online) (doi:10.1007/s13311-023-01355-7)
Innovation Fund Award 2023 from the University of Greenwich
Tabassum, Sobia, Shorter, Susan and Ovsepian, Saak V. (2024) Analysis of the action mechanisms and targets of herbal anticonvulsants highlights opportunities for therapeutic engagement with refractory epilepsy. Journal of Molecular Medicine, 102. pp. 761-771. ISSN 0946-2716 (Print), 1432-1440 (Online) (doi:10.1007/s00109-024-02445-5)
Innovation Fund Award from the University of Greenwich
Jorratt, Pascal, Ricny, Jan, Leibold, Christian and Ovsepian, Saak (2022) Endogenous modulators of NMDA receptor control dendritic field expansion of cortical neurons. Molecular Neurobiology. ISSN 0893-7648 (Print), 1559-1182 (Online) (doi:10.1007/s12035-022-03147-0)
Instituto de Salud Carlos III (“RD16/001/0010”, co-funded by ERDF)
Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:10.1007/s00429-023-02728-6)
MINECO/AEI/ERDF, EU, Spanish State Research Agency, and the European Union via the European Regional Development Fund (ERDF)—“Una manera de hacer Europa” (SAF2017-83702-R)
Ovsepian, Saak, O'Leary, Valerie B and Martinez, Salvador (2023) Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Brain Structure and Function. ISSN 1863-2653 (Print), 1863-2661 (Online) (doi:10.1007/s00429-023-02728-6)
Medical Diagnostics and Basic Medical Sciences
Zhang, Grace, Devo, Perry ORCID: https://orcid.org/0000-0003-1487-8896, O'Leary, Valerie B. ORCID: https://orcid.org/0000-0003-1171-9830 and Ovsepian, Saak ORCID: https://orcid.org/0000-0002-9522-4159 (2023) Ageing perspective on cognitive outcomes from auxiliary reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:10.1016/j.heliyon.2023.e19050)
Medical Diagnostics and Basic Medical Sciences in ‘Medical Genetics’
Ovsepian, Saak and O'Leary, Valerie (2022) Adult neurogenesis in the gut, homeostatic autoimmunity and neurodegenerative disease biomarkers. Neuroscience, 10 (504). pp. 75-78. ISSN 0306-4522 (doi:10.1016/j.neuroscience.2022.09.019)
Ministry of Education, Youth and Sports of the Czech Republic
Kutna, Viera, O'Leary, Valerie Brid, Hoschl, Cyril and Ovsepian, Saak V. (2022) Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism Research, 15 (5). pp. 791-805. ISSN 1939-3792 (Print), 1939-3806 (Online) (doi:10.1002/aur.2688)
Jorratt, Pascal, Hoschl, Cyril and Ovsepian, Saak (2021) Endogenous antagonists of N-Methyl-D-Aspartate receptor in schizophrenia. Alzheimers and Dementia, 17 (5). pp. 888-905. ISSN 1552-5279 (Print), 1552-5279 (Online) (doi:10.1002/alz.12244)
Kutna, Viera, O'Leary, Valerie, Newman, Ehren, Hoschl, Cyril and Ovsepian, Saak (2021) Revisiting brain tuberous sclerosis complex in rat and human: shared molecular and cellular pathology leads to distinct neurophysiological and behavioural phenotypes. Neurotherapeutics - The Journal of the American Society for Experimental Neurotherapeutics, 18 (2). pp. 845-858. ISSN 1933-7213 (Print), 1878-7479 (Online) (doi:10.1007/s13311-020-01000-7)
Ovsepian, Saak, O'Leary, Valerie and Hoschl, Cyril (2021) Mainstream psychiatry reinstates therapeutic ventures of the remote past. Drug Discovery Today, 26 (3). pp. 845-851. ISSN 1359-6446 (Print), 1359-6446 (Online) (doi:10.1016/j.drudis.2021.01.011)
Ministry of Education, Youth and Sports of the Czech Republic under the NPU I program and GAUK 365121 (Charles University Grant Agency)
Jorratt, Pascal, Ricny, Jan, Leibold, Christian and Ovsepian, Saak (2022) Endogenous modulators of NMDA receptor control dendritic field expansion of cortical neurons. Molecular Neurobiology. ISSN 0893-7648 (Print), 1559-1182 (Online) (doi:10.1007/s12035-022-03147-0)
Ministry of Education, Youth, and Sports of the Czech Republic
Ovsepian, Saak, O'Leary, Valerie, Hoschl, Cyril and Zaborszky, Laszlo (2021) Integrated phylogeny of the human brain and pathobiology of Alzheimer's disease: a unifying hypothesis. Neuroscience Letters, 11 (755):135895. pp. 1-9. ISSN 0304-3940 (Print), 0304-3940 (Online) (doi:10.1016/j.neulet.2021.135895)
Vrajova, Monika, Slamberova, Romana, Hoschl, Cyril and Ovsepian, Saak (2021) Methamphetamine and sleep impairments: neurobehavioral correlates and molecular mechanisms. Sleep, 44 (6):zsab001. ISSN 0161-8105 (Print), 1550-9109 (Online) (doi:10.1093/sleep/zsab001)
National Institute of Mental Health (Grant No. 00023752)
Granak, Simon, Tuckova, Klara, Kutna, Viera, Vijtechova, Iveta, Bajkova, Laura, Petrasek, Tomas and Ovsepian, Saak (2022) Developmental effects of the impact of constitutive mTORC1 hyperactivity and environmental enrichment on structural synaptic plasticity and behaviour in a rat model of autism spectrum disorder. European Journal of Neuroscience, 57 (1). pp. 17-31. ISSN 0953-816X (Print), 1460-9568 (Online) (doi:10.1111/ejn.15864)
National Institute of Mental Health (Grant No. LO1611; PROGRES 260533/SVV/2021 Neurology)
Kutna, Viera, O'Leary, Valerie Brid, Hoschl, Cyril and Ovsepian, Saak V. (2022) Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism Research, 15 (5). pp. 791-805. ISSN 1939-3792 (Print), 1939-3806 (Online) (doi:10.1002/aur.2688)
National Institute of Mental Health (NIMH, IN: 00023752) under grant number LO1611, from the Ministry of Education, Youth and Sports of the Czech Republic under the NPU I program
Kocurova, Gabriela, Ricny, Jan and Ovsepian, Saak (2022) Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases. Theranostics, 12 (7). pp. 3045-3056. ISSN 1838-7640 (Online) (doi:10.7150/thno.72126)
Nurology SVV grant 260648/SVV/2023: Research of drug addiction and neuropsychiatric diseases—from the basic research to the clinical practic
Pokorná, Markéta, Kútna, Viera, Ovsepian, Saak V., Matěj, Radoslav, Cerná, Marie and Brid O'Leary, Valerie (2024) Biomolecules to biomarkers? U87MG marker evaluation on the path towards glioblastoma multiforme pathogenesis. Pharmaceutics, 16 (1):123. pp. 1-16. ISSN 1999-4923 (Print), 12 January 2024 / Published: 18 January 2024 (Online) (doi:10.3390/pharmaceutics16010123)
Sustainability for the National Institute of Mental Health (NIMH, IN: 00023752) under grant number LO1611
Jorratt, Pascal, Ricny, Jan, Leibold, Christian and Ovsepian, Saak (2022) Endogenous modulators of NMDA receptor control dendritic field expansion of cortical neurons. Molecular Neurobiology. ISSN 0893-7648 (Print), 1559-1182 (Online) (doi:10.1007/s12035-022-03147-0)
The neurology SVV grant 260648/SVV/2023: Research of drug addiction and neuropsychiatric diseases—from the basic research to the clinical practice.
Pokorná, Markéta, Cern, Marie, Boussios, Stergios, Ovsepian, Saak V. and Bríd O’Leary, Valerie (2024) lncRNA biomarkers of glioblastoma multiforme. Biomedicines, 12:932. pp. 1-37. ISSN 2227-9059 (Online) (doi:10.3390/biomedicines12050932)
University of Greenwich
Zhang, Grace, Devo, Perry ORCID: https://orcid.org/0000-0003-1487-8896, O'Leary, Valerie B. ORCID: https://orcid.org/0000-0003-1171-9830 and Ovsepian, Saak ORCID: https://orcid.org/0000-0002-9522-4159 (2023) Ageing perspective on cognitive outcomes from auxiliary reproductive hormone adjustments. Heliyon, 9 (8):E19050. pp. 1-7. ISSN 2405-8440 (Online) (doi:10.1016/j.heliyon.2023.e19050)