Article

Zhou, Jiabao, Down, Jennifer M, George, Christopher N, Murphy, Jessica, Lefley, Diane V, Tulotta, Claudia, Alsharif, Marwa A, Leach, Michael ORCID: 0000-0002-9859-1325 and Ottewell, Penelope D (2022) Novel methods of targeting IL-1 signalling for the treatment of breast cancer bone metastasis. Cancers, 14 (19):4816. ISSN 2072-6694 (Online) (doi:https://doi.org/10.3390/cancers14194816)

Walsh, Yvonne, Leach, Michael ORCID: 0000-0002-9859-1325 , Veale, Emma and Mathie, Alistair (2021) Block of TREK and TRESK K2P channels by lamotrigine and two derivatives sipatrigine, and CEN-092. Biochemistry and Biophysics Reports, 26:101021. ISSN 2405-5808 (doi:https://doi.org/10.1016/j.bbrep.2021.101021)

Palmer, Rex A., Potter, Brian S., Leach, Michael J. ORCID: 0000-0002-9859-1325 , Jenkins, Terence C. and Chowdhry, Babur Z. (2010) An absolute structure template for a unique voltage-gated sodium channel binding site. MedChemComm, 1 (1). pp. 45-49. ISSN 2040-2503 (Print), 2040-2511 (Online) (doi:https://doi.org/10.1039/C0MD00043D)

Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: 0000-0002-9859-1325 and Harbige, L.S. (2010) Decreased monocyte chemoattractant protein 1 and relationship with 15-deoxy-delta 12,14- prostaglandin J2 in gamma-linolenic acid supplemented healthy subjects. Proceedings of the Nutrition Society, 69 (OCE3). E325-E325. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:https://doi.org/10.1017/S002966511000114X)

Palmer, Rex A., Potter, Brian S., Helliwell, Madeleine, Leach, Michael J. ORCID: 0000-0002-9859-1325 and Chowdhry, Babur Z. (2008) Central nervous system drugs: Low temperature X-ray structures of (I) the base 5-(2,3-dichlorophenyl)-2,4-diamino-6-fluoromethyl-pyrimidine (4030W92) and (II) 5-(2,6-dichlorophenyl)-1-H-2,4-diamino-6-methyl-pyrimidine methanesulphonic acid salt (227C89). Journal of Chemical Crystallography, 39 (1). pp. 36-41. ISSN 1074-1542 (Print), 1572-8854 (Online) (doi:https://doi.org/10.1007/s10870-008-9428-5)

Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: 0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:https://doi.org/10.1017/S0029665108006538)

Harbige, L.S., Pinto, E., Xiang, M., Leach, M. ORCID: 0000-0002-9859-1325 and Sharief, M. K. (2008) PUFA in the pathogenesis and treatment of patients with multiple sclerosis. Proceedings of the Nutrition Society, 67 (OCE1). E21. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:https://doi.org/10.1017/S0029665108006307)

Palmer, Rex A., Potter, Brian S., Leach, Michael J. ORCID: 0000-0002-9859-1325 and Chowdhry, Babur Z. (2008) X-ray crystallographic structures of two lamotrigine analogues: (I) 3,5-diamino-6-(2-chlorophenyl)-1,2,4-triazine water solvate and (II) 3,5-diamino-6-(3,6-dichlorophenyl)-1,2,4-triazine methanol solvate. Journal of Chemical Crystallography, 38 (5). pp. 387-392. ISSN 1074-1542 (Print), 1572-8854 (Online) (doi:https://doi.org/10.1007/s10870-008-9320-3)

Palmer, Rex A., Potter, Brian S., Leach, Michael J. ORCID: 0000-0002-9859-1325 and Chowdhry, Babur Z. (2008) Low temperature X-ray crystallographic structures of two lamotrigine analogues: (I) 2-methyl,3-amino, 5-imino-6-(2,3-dichlorophenyl)-1,2,4-triazine water solvate and (II) 2-methyl,3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine isethionate, hemi-hydrate. Journal of Chemical Crystallography, 38 (4). pp. 255-260. ISSN 1074-1542 (Print), 1572-8854 (Online) (doi:https://doi.org/10.1007/s10870-008-9318-x)

Palmer, Rex A., Potter, Brian S., Leach, Michael J. ORCID: 0000-0002-9859-1325 and Chowdhry, Babur Z. (2008) Low temperature X-ray structures of two crystalline forms (I) and (II) of the pyrimidine derivative and sodium channel blocker BW1003C87: 5-(2,3,5-trichlorophenyl)-2,4-diaminopyrimidine. Journal of Chemical Crystallography, 38 (6). pp. 407-411. ISSN 1074-1542 (Print), 1572-8854 (Online) (doi:https://doi.org/10.1007/s10870-008-9319-9)

Palmer, Rex A., Potter, Brian S., Leach, Michael J. ORCID: 0000-0002-9859-1325 and Chowdhry, Babur Z. (2007) X-ray crystallographic structures of neuroprotective pyrimidine derivatives: (I) the mesylate salt of BW1003C87 and (II) sipatrigine base. Journal of Chemical Crystallography, 37 (11). pp. 771-777. ISSN 1074-1542 (Print), 1572-8854 (Online) (doi:https://doi.org/10.1007/s10870-007-9248-z)

Riddall, Dieter R., Leach, Michael J. ORCID: 0000-0002-9859-1325 and Garthwaite, John (2006) A novel drug binding site on voltage-gated sodium channels in rat brain. Molecular Pharmacology, 69 (1). pp. 278-287. ISSN 1521-0111 (Online) (doi:https://doi.org/10.1124/mol.105.015966)

Conference or Conference Paper

Harbige, L. S., Hollifield, R. D., Pinto, E., Xiang, M., Leach, M. ORCID: 0000-0002-9859-1325 and Sharief, M. K. (2006) Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 July 2006, Cairns Convention Centre, Cairns, Queensland, Australia. (Unpublished)

Pinto, E., Xiang, M., Leach, M. ORCID: 0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)

Patent

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