Bitter APIs; Hot melt extrusion; Inter-molecular interactions; Modified release; Molecular dispersion; Taste assessment; Taste masking

Maniruzzaman, Mohammed, Boateng, Joshua ORCID: 0000-0002-6310-729X , Chowdhry, Babur, Snowden, Martin ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2013) A review on the taste masking of bitter APIs: Hot-melt extrusion (HME) evaluation. Drug Development and Industrial Pharmacy, 40 (2). pp. 145-156. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.3109/03639045.2013.804833)

Centella asiatica; burn; cytokine; collagen; contraction; wound granulation; re-epithelialization; wound healing

Arribas-López, Elena, Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 , Ojo, Omorogieva ORCID: 0000-0003-0071-3652 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Kochhar, Tony (2022) A systematic review of the effect of Centella asiatica on wound healing. International Journal of Environmental Research and Public Health, 19 (6):3266. pp. 1-13. ISSN 1661-7827 (Online) (doi:https://doi.org/10.3390/ijerph19063266)

Colloid microgel; Flocculation

Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2016) Colloidal microgels - untapped potential? Journal of Nanomedicine and Nanotechnology, 7 (4). pp. 1-2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000e142)

Colloidal microgels; Microgel particles; Cotion samples; Attachment techniques

Majcen, Natasa, Mohsen, Reham, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2018) The development of a novel smart material based on colloidal microgels and cotton. Advances in Colloid and Interface Science, 256. pp. 193-202. ISSN 0001-8686 (Print), 1095-7103 (Online) (doi:https://doi.org/10.1016/j.cis.2018.04.005)

Commercial, Complementary, Baby food, Macronutrients, Chemical analysis, Nutritional profiling, Labelling and legislation

Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 , Chowdhry, Babur, Pollard, Lucy, Pullen, Francis, Snowden, Martin ORCID: 0000-0002-1087-2692 and Zotor, Francis (2015) Commercial ‘ready-to-feed’ infant foods in the UK: macro-nutrient content and composition. Maternal & Child Nutrition, 11 (2). pp. 202-214. ISSN 1740-8695 (Print), 1740-8709 (Online) (doi:https://doi.org/10.1111/j.1740-8709.2012.00445.x)

Dissolution rate, Flurbiprofen, Inclusion complexes, Methyl–β–cyclodextrin, Solubility, Supercritical fluid technology

Rudrangi, Shashi Ravi Suman, Kaialy, Waseem, Ghori, Muhammad U., Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Alexander, Bruce David and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2016) Solid-state flurbiprofen and methyl-β-cyclodextrin inclusion complexes prepared using a single-step, organic solvent-free supercritical fluid process. European Journal of Pharmaceutics and Biopharmaceutics, 104. pp. 164-170. ISSN 0939-6411 (doi:https://doi.org/10.1016/j.ejpb.2016.04.024)

Granulations; DoE; QbD; Dissolutions; Twin screw; Raman; DVS

Maniruzzaman, Mohammed, Nair, Arun, Renault, Maxcene, Nandi, Uttom ORCID: 0000-0003-1777-3862 , Scoutaris, Nicholaos, Farnish, Richard, Bradley, Mike, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2015) Continuous twin-screw granulation for enhancing the dissolution of poorly water soluble drug. International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”, 496 (1). ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.025)

Heckel equation; Deformation; Yield pressure; Linear regression; True density

Hooper, D., Clarke, F.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2016) A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt. Journal of Nanomedicine and Nanotechnology, 7 (381). p. 2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000381)

Hot melt extrusion; Taste masking; Solubility increase; Process technology; Formulation

Maniruzzaman, Mohammed, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2012) A review of hot-melt extrusion: process technology to pharmaceutical products [Review article]. ISRN Pharmaceutics, 2012:436763. pp. 1-9. ISSN 2090-6145 (Print), 2090-6153 (Online) (doi:https://doi.org/10.5402/2012/436763)

Indomethacin, In-line monitoring, Reflectance; Transmission, Near infrared spectroscopy, Process analytical technology, Hot-melt extrusion, Molecular solutions, Raman mapping

Islam, Muhammad T., Scoutaris, Nikolaos, Maniruzzaman, Mohammed, Moradiya, Hiren G., Halsey, Sheelagh, Bradley, Michael, Chowdhry, Babur, Snowden, Martin ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2015) Implementation of transmission NIR as a PAT tool for monitoring drug transformation during HME processing. European Journal of Pharmaceutics and Biopharmaceutics, 96. pp. 106-116. ISSN 0939-6411 (Print), 1873-3441 (Online) (doi:https://doi.org/10.1016/j.ejpb.2015.06.021)

Inorganic excipients; Solid dispersions; Continuous extrusion

Maniruzzaman, M., Nair, A., Scoutaris, N., Bradley, Michael S.A., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2015) One-step continuous extrusion process for the manufacturing of solid dispersions. International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”, 496 (1). pp. 42-51. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.048)

LC-MS/MS assays

Alfazema, L.N., Richards, D.S., Gelebart, S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Achieving high accuracy and precision in LC-MS/MS assays for pharmaceutical analysis. Journal of Pharmacy and Pharmacology, 57 (S1). S47-S47. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248613)

NMR, C-13, N-15, dynamic nuclear polarisation, heteronuclear

Day, Iain, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Co-acquisition of hyperpolarised 13C and 15N NMR spectra. Magnetic Resonance in Chemistry, 45 (12). pp. 1018-1021. ISSN 0749-1581 (Print), 1097-458X (Online) (doi:https://doi.org/10.1002/mrc.2090)

Nutraceuticals; Fish oil microencapsulation; Hydroxy propyl methyl cellulose acetate succinate (HPMCAS); Docosahexaenoic acid (DHA); Spray-drying; Solid lipid nanoparticle (SLN)

Loughrill, Emma, Thompson, Sharon, Owusu-Ware, Samuel K., Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Douroumis, Dennis ORCID: 0000-0002-3782-0091 and Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 (2019) Controlled release of microencapsulated docosahexaenoic acid (DHA) by spray–drying processing. Food Chemistry, 286. pp. 368-375. ISSN 0308-8146 (doi:https://doi.org/10.1016/j.foodchem.2019.01.121)

PCS, cationic poly(NIPAM/BA/4-vinylpyridine), mole fraction composition, thermodynamic parameters, thermodynamic activity, reference state

Pinkrah, Victoria T., Beezer, Anthony E., Chowdry, Babur Z., Gracia, Louise H., Cornelius, Victoria J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Castro-Lopez, Vanessa and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Swelling of cationic polyelectrolyte colloidal microgels: thermodynamic considerations. Colloids and Surfaces A: Physiochemical and Engineering Aspects, 262 (1-3). pp. 76-80. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2005.04.022)

Particle shape; Surface energy; Punch sticking; Crystal chemistry

Hooper, D., Clarke, F. C., Docherty, R., Mitchell, J. C. ORCID: 0000-0003-2945-3292 and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2017) Effects of crystal habit on the sticking propensity of ibuprofen — A case study. International Journal of Pharmaceutics, 531 (1). pp. 266-275. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.08.091)

Pharmaceutics, Molecular, Modelling Drug Delivery,

Douroumis, Dionysios ORCID: 0000-0002-3782-0091 , Fahr, A., Siepmann, J. and Snowden, Martin ORCID: 0000-0002-1087-2692 (eds.) (2015) Computational pharmaceutics: application of molecular modeling in drug delivery. Advances in Pharmaceutical Technology . Wiley-Blackwell. ISBN 978-1118573990

Pickering emulsion, creosote, remediation, porous media

Torres, Luis, Iturbe, Rosario, Snowden, M. J. ORCID: 0000-0002-1087-2692 , Chowdhry, B. Z. and Leharne, Stephen (2007) Can Pickering emulsion formation aid the removal of creosote DNAPL from porous media? Chemosphere, 71 (1). pp. 123-132. ISSN 0045-6535 (doi:https://doi.org/10.1016/j.chemosphere.2007.09.053)

Pluronics, Carbon dioxide

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John ORCID: 0000-0003-2945-3292 , Coleman, Nichola and Snowden, Martin ORCID: 0000-0002-1087-2692 (2014) Effect of pressure on the melting point of pluronics in pressurized carbon dioxide. Industrial & Engineering Chemistry Research, 53 (26). pp. 10820-10825. ISSN 0888-5885 (doi:https://doi.org/10.1021/ie501344m)

Polymers, Microgel, Fluorescence

Mohsen, R., Alexander, B. D., Richardson, S. C. W. ORCID: 0000-0002-7927-0649 , Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Diab, A. A. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2016) Design, synthesis, characterization and toxicity studies of Poly (N-Iso-Propylacrylamide-co-Lucifer Yellow) particles for drug delivery applications. Journal of Nanomedicine and Nanotechnology, 7 (2):1000363. pp. 363-372. ISSN 2157-7439 (doi:https://doi.org/10.4172/2157-7439.1000363)

Polymorphic transformation; Sulfanilamide; Diffuse reflectance visible spectroscopy; Powder X-ray diffraction; Differential scanning Calorimetry

Ehiwe, Tracy O., Alexander, Bruce D, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Waters, Laura J. (2016) Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy. Journal of Pharmaceutical Analysis, 6 (3). ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2015.12.002)

QSPR, enantiomeric excess, catalysis

Morao, I., Higginson, P.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) GRIND-based QSPR method to predict the enantiomeric excess in catalysis. Journal of Pharmacy and Pharmacology, 57 (S1). S31-S31. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248343)

Raman chemical images, univariate data processing, multivariate data processing

Sasic, Slobaban, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) A comparison of Raman chemical images produced by univariate and multivariate data processing - a simulation with an example from pharmaceutical practice. The Analyst, 129 (11). pp. 1001-1007. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B409879J)

Raman line mapping

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Raman line mapping as a fast method for analyzing pharmaceutical bead formulations. The Analyst, 130 (11). pp. 1530-1536. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B506523B)

Raman maps, pharmaceutical products, two-dimensional correlation, 2D correlation, sample-sample

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Analyzing Raman maps of pharmaceutical products by sample-sample two-dimensional correlation. Applied Spectroscopy, 59 (5). pp. 630-638. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/0003702053946047)

Raman spectroscopy, FTIR spectroscopy, deuterated isotopomers, spectral assignments, cis-/trans-conformation, ab initio calculations

Mendham, Andrew P., Dines, Trevor J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Chowdhry, Babur Z. and Withnall, Robert (2009) Vibrational spectroscopy and DFT calculations of di-amino acid cyclic peptides. Part I: cyclo(Gly-Gly), cyclo(L-Ala-L-Ala) and cyclo(L-Ala-Gly) in the solid state and in aqueous solution. Journal of Raman Spectroscopy, 40 (11). pp. 1478-1497. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2293)

SMART wound dressings, matrices, molecules, networks, particles, polymers, veins, wound healing

Cornelius, Victoria J., Majcen, Natasa, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2006) Preparation of SMART wound dressings based on colloidal microgels and textile fibres. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130X (6413). Society of Photo-Optical Instrumentation Engineers (SPIE). ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712573)

Solid, Dispersions, Surface, Analysis

Maniruzzaman, Mohammed, Snowden, Martin ORCID: 0000-0002-1087-2692 , Bradley, Michael and Douroumis, Dionysios ORCID: 0000-0002-3782-0091 (2015) Correction: Studies of intermolecular interactions in solid dispersions using advanced surface chemical analysis. RSC Advances, 5 (103). p. 84936. ISSN 2046-2069 (Online) (doi:https://doi.org/10.1039/c5ra90091c)

Wet granulation; DoE; QbD; Dissolution rate; Specific surface area; Water sorption

Maniruzzaman, Mohammed, Ross, Steven A., Dey, Tumpa, Nair, Arun, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2017) A quality by design (QbD) twin–screw extrusion wet granulation approach for processing water insoluble drugs. International Journal of Pharmaceutics, 526 (1-2). pp. 496-505. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.05.020)

accuracy, time dilemma, prediction, NMR chemical shifts, chloropyrimidines

Pérez, Manuel, Peakman, Torren M., Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Iñaki (2006) Accuracy vs time dilemma on the prediction of NMR chemical shifts: a case study (chloropyrimidines). The Journal of Organic Chemistry, 71 (8). pp. 3103-3110. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo0600149)

accuracy. precision, 5-methoxytryptamine, amitriptyline, quantitative MS/MS, chip-based nanoelectrospray

Alfazema, Louisa N., Richards, Don S., Gélébart, Sylvie, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Rapid, accurate and precise quantitative drug analysis: comparing liquid chromatography tandem mass spectrometry and chip-based nanoelectrospray ionisation mass spectrometry. European Journal of Mass Spectrometry, 11 (4). pp. 393-402. ISSN 1469-0667 (Print), 1356-1049 (Online) (doi:https://doi.org/10.1255/ejms.772)

advanced surface chemical analysis; drug/polymer interactions

Maniruzzaman, Mohammed, Snowden, Martin ORCID: 0000-0002-1087-2692 , Bradley, Michael and Douroumis, Dionysios ORCID: 0000-0002-3782-0091 (2015) Studies of intermolecular interactions in solid dispersions using advanced surface chemical analysis. RSC Advances: An international journal to further the chemical sciences, 5 (91). pp. 74212-74219. ISSN 2046-2069 (Online) (doi:https://doi.org/10.1039/C5RA13176F)

arginine; collagen deposition; contraction; food; glutamine; growth factor; gut permeability; interleukin; re-epithelialization; wound healing

Arribas Lopez, Elena, Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 , Ojo, Omorogieva ORCID: 0000-0003-0071-3652 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Kochhar, Tony (2021) The effect of amino acids on wound healing: a systematic review and meta-analysis on arginine and glutamine. Nutrients, 13 (8):2498. ISSN 2072-6643 (Print), 2072-6643 (Online) (doi:https://doi.org/10.3390/nu13082498)

bentonite, kaolin, oscillatory rheology, pickering emulsions, sand

Torres, L. G., Iturbe, R., Snowden, M. J. ORCID: 0000-0002-1087-2692 , Chowdhry, B. Z. and Leharne, S. A. (2007) Preparation of o/w emulsions stabilized by solid particles and their characterization by oscillatory rheology. Colloids and Surfaces A: Physiochemical and Engineering Aspects, 302 (1-3). pp. 439-448. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2007.03.009)

catalysts, imidazolide coupling

Dunn, P.J., Hoffmann, W., Kang, Y., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) A comparison of catalysts to promote imidazolide couplings including the identification of 2-hydroxy-5-nitropyridine as a new, safe and effective catalyst. Journal of Pharmacy and Pharmacology, 57 (S1). S32-S33. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248451)

chemical modification, edible film, polysaccharide pullulan

Gibson, G.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Chemical modification of the edible film polysaccharide pullulan. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 50-51. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489249)

chirality, salt formation

Johnson, M.N., Feeder, N., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Effects of chirality on the salt formation of histidine. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 24-25. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

colloidal microgels, absorption, dispersion, molecules, mouth, stomach

Cornelius, Victoria J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2006) The use of colloidal microgels for the controlled delivery of proteins and peptides. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130Y (6413). Society of Photo-Optical Instrumentation Engineers (SPIE), Bellingham, Washington USA. ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712578)

colloidal microgels, biodiesel, Karl Fischer, dispersibility, water absorbent, n-isopropylacrylamide, temperature, transesterification, copolymer, hydrogels, colloids

Nur, H., Snowden, M. J. ORCID: 0000-0002-1087-2692 , Cornelius, V. J., Mitchell, J. C. ORCID: 0000-0003-2945-3292 , Harvey, P. J. ORCID: 0000-0001-7193-4570 and Benee, L. S. (2008) Colloidal microgel in removal of water from biodiesel. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 335 (1-3). pp. 133-137. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2008.10.049)

colloids, p(NIPAM), acrylic acid, DLS, rheology, particle concentration, membrane blockage

Mohsen, Reham, Vine, George J., Majcen, Natasa, Alexander, Bruce D, and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2013) Characterization of thermo and pH responsive NIPAM based microgels and their membrane blocking potential. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 428. pp. 53-59. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2013.03.031)

commercial, complementary, baby food, macronutrients, chemical analysis, nutritional profiling, labelling and legislation

Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 , Chowdhry, Babur Z., Pollard, Lucie V., Pullen, Frank, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Zotor, Francis (2012) Commercial 'ready-to-feed' infant foods in the UK: Macro-nutrient content and composition. Maternal & Child Nutrition, 11 (2). pp. 202-214. ISSN 1740-8695 (Print), 1740-8709 (Online) (doi:https://doi.org/10.1111/j.1740-8709.2012.00445.x)

commercial, complementary, macronutrient, chemical analysis, labelling and legislation

Zand Fard, Nazanin ORCID: 0000-0003-2058-2354 , Chowdhry, Babur Z., Pollard, Lucie V., Pullen, Francis, Snowden, Martin ORCID: 0000-0002-1087-2692 and Zotor, Francis B. (2011) Commercial infant foods in the UK: macro-nutrient content and composition. Proceedings of the Nutrition Society, 70 (OCE4). E159. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:https://doi.org/10.1017/S0029665111002102)

compositional analysis, colloidal microgels

Gracia, L.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Humphrey, M.J. (2005) The structural and compositional analysis of colloidal microgels and their development as controlled absorption/release devices. Journal of Pharmacy and Pharmacology, 57 (S1). S61-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

continuous cocrystallisation, carbamazepine, trans-cinnamic acid, melt extrusion processing

Moradiya, Hiren G., Islam, Muhammad T., Halsey, Sheelagh, Maniruzzaman, Mohammed, Chowdhry, Babur Z., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2014) Continuous cocrystallisation of carbamazepine and trans-cinnamic acid via melt extrusion processing. CrystEngComm, 16 (17). pp. 3573-3583. ISSN 1466-8033 (doi:https://doi.org/10.1039/c3ce42457j)

counter-current chromatography, solvent system selection, pharmaceutical, statistical approach

Dubant, Stéphane, Mathews, Ben, Higginson, Paul, Crook, Robert, Snowden, Martin ORCID: 0000-0002-1087-2692 and Mitchell, John ORCID: 0000-0003-2945-3292 (2008) Practical solvent system selection for counter-current separation of pharmaceutical compounds. Journal of Chromatography A, 1207 (1-2). pp. 190-192. ISSN 0021-9673 (doi:https://doi.org/10.1016/j.chroma.2008.08.113)

crosslinked pullulan

Gibson, G.H., Auffret, A.D., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Synthesis and characterisation of hydrophobically modified and crosslinked pullulan with enhanced viscosity characteristics. Journal of Pharmacy and Pharmacology, 57 (S1). S62-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

cyclic di-amino acid peptides, CDAP, X-ray crystallography, ab initio calculations, vibrational spectra

Mendham, Andrew P., Dines, Trevor J., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Withnall, Robert and Chowdhry, Babur Z. (2009) IR/Raman spectroscopy and DFT calculations of cyclic di-amino acid peptides. Part III: comparison of solid state and solution structures of cyclo(L-Ser-L-Ser). Journal of Raman Spectroscopy, 40 (11). pp. 1508-1520. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2306)

cyclic di-amino acid peptides, X-ray crystallography, ab initio calculations, vibrational spectra

Mendham, Andrew P., Palmer, Rex A., Potter, Brian S., Dines, Trevor J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Withnall, Robert and Chowdhry, Babur Z. (2009) Vibrational spectroscopy and crystal structure analysis of two polymorphs of the di-amino acid peptide cyclo(L-Glu-L-Glu). Journal of Raman Spectroscopy, 41 (3). pp. 288-302. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2467)

dissolution, dynamic nuclear polarization method, acquisition, relaxation, spectra, times

Day, I.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Snowden, M.J. ORCID: 0000-0002-1087-2692 and Davis, A.L. (2008) Investigation of the potential of the dissolution dynamic nuclear polarization method for general sensitivity enhancement in small-molecule NMR spectroscopy. Applied Magnetic Resonance, 34 (3-4). pp. 453-460. ISSN 0937-9347 (Print), 1613-7507 (Online) (doi:https://doi.org/10.1007/s00723-008-0122-8)

dynamic nuclear polarisation, spin-lattice relaxation, heteronuclear

Day, Iain J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times. Journal of Magnetic Resonance, 187 (2). pp. 216-224. ISSN 1090-7807 (doi:https://doi.org/10.1016/j.jmr.2007.04.015)

e-tongue, hot-melt extrusion, molecular dispersions, taste masking

Maniruzzaman, Mohammed, Bonnefille, Marion, Aranyos, Attila, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2013) An in-vivo and in-vitro taste masking evaluation of bitter melt-extruded drugs. Journal of Pharmacy and Pharmacology, 66 (2). pp. 323-337. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/jphp.12169)

enantiomeric excess, asymmetric catalysis

Sciabola, Simone, Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Inaki (2005) Theoretical prediction of the enantiomeric excess in asymmetric catalysis. An alignment-independent molecular interaction field based approach. The Journal of Organic Chemistry, 70 (22). pp. 9025-9027. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo051496b)

evaporative light-scattering detector, ELSD, column liquid chromatography, detector calibration

Mathews, B.T., Higginson, P.D., Lyons, R., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Sach, N.W., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Taylor, M.R. and Wright, A.G. (2004) Improving quantitative measurements for the evaporative light scattering detector. Chromatographia, 60 (11-12). pp. 625-633. ISSN 0009-5893 (Print), 1612-1112 (Online) (doi:https://doi.org/10.1365/s10337-004-0441-3)

fatty acids, supercritical fluids, melting point depression

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Coleman, Nichola J., Douroumis, Dennis ORCID: 0000-0002-3782-0091 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2013) Study of the effect of pressure on melting behavior of saturated fatty acids in liquid or supercritical carbon dioxide. Journal of Chemical & Engineering Data, 58 (6). pp. 1861-1866. ISSN 0021-9568 (Print), 1520-5134 (Online) (doi:https://doi.org/10.1021/je400260c)

fluorescent p(NIPAM), vinyl cinnamate, quantitative particle deposition, surface charge and surface roughness

Mohsen, Reham, Thorne, Joanna B., Alexander, Bruce D. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2014) Deposition of fluorescent NIPAM-based nanoparticles on solid surfaces: quantitative analysis and the factors affecting it. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 457. pp. 107-115. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2014.05.050)

fracture toughness, nanoindentation, pharmaceutical --------------------------------------------------------------------------------

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Mechanical characterisation of powders using nanoindentation. Powder Technology, 143-4. pp. 179-185. ISSN 0032-5910 (doi:https://doi.org/10.1016/j.powtec.2004.04.012)

heteroflocculation, microgels, colloidal poly(N-isoproprylacrylamide)

Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Gracia, Louise H. and Nur, Hani (2008) Heteroflocculation studies of colloidal poly(N-isoproprylacrylamide) microgels with polystyrene latex particles: Effect of particle size, temperature and surface charge. In: Biggs, Simon, Cosgrove, Terence and Dowding, Peter, (eds.) New frontiers in colloidal science: a celebration of the career of Simon Vincent. Royal Society of Chemistry Publishing, pp. 148-165. ISBN 978-1-84755-843-5, 978-0-85404-113-8 (print) (doi:https://doi.org/10.1039/9781847558435-00148)

hot melt extrusion, lipid matrices, surface mapping, sustained release

Vithani, K., Cuppok, Y., Mostafa, S., Slipper, I. J., Snowden, M. J. ORCID: 0000-0002-1087-2692 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2014) Diclofenac sodium sustained release hot melt extruded lipid matrices. Pharmaceutical Development and Technology, 19 (5). pp. 531-538. ISSN 1083-7450 (Print), 1097-9867 (Online) (doi:https://doi.org/10.3109/10837450.2013.805775)

identification, catalysts,imidazolide couplings, reaction conditions, kinetic modelling

Bright, Robert, Dale, David J., Dunn, Peter J., Hussain, Farhat, Kang, Ying, Mason, Clive, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) Identification of new catalysts to promote imidazolide couplings and optimisation of reaction conditions using kinetic modelling. Organic Process Research & Development, 8 (6). pp. 1054-1058. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op049874m)

infants, commercial complementary foods, riboflavin and pyridoxine content, nutritional information, simultaneous digestion and extraction, UHPLC, 23 LC–M

Zand, Nazanin ORCID: 0000-0003-2058-2354 , Chowdhry, Babur Z., Pullen, Frank S., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Tetteh, John (2012) Simultaneous determination of riboflavin and pyridoxine by UHPLC/LC–MS in UK commercial infant meal food products. Food Chemistry, 135 (4). pp. 2743-2749. ISSN 0308-8146 (doi:https://doi.org/10.1016/j.foodchem.2012.07.064)

infants, complementary foods, commercial infant food products, elemental content [essential, trace and non-essential (toxic)], food labelling, risk exposure, ICP-OES, ICP-MS

Zand, Nazanin ORCID: 0000-0003-2058-2354 , Chowdhry, Babur Z., Wray, David S. ORCID: 0000-0002-0799-2730 , Pullen, Frank S. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2012) Elemental content of commercial ‘ready to-feed’ poultry and fish based infant foods in the UK. Food Chemistry, 135 (4). pp. 2796-2801. ISSN 0308-8146 (doi:https://doi.org/10.1016/j.foodchem.2012.07.034)

isothermal titration calorimetry, potentiometric titration, protonation, cationic colloidal microgel, 4-Vinylpyridine, co-polymer

Seidel, J., Pinkrah, V.T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Chowdhry, B.Z. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Isothermal titration calorimetric studies of the acid-base properties of poly (N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Thermochimica Acta, 414 (1). pp. 47-52. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.11.012)

jet dispensing, printing, taste masking, water insoluble drugs

Scoutaris, Nikolaos, Snowden, Martin ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2015) Taste masked thin films printed by jet dispensing. International Journal of Pharmaceutics, 494 (2). pp. 619-622. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2015.05.018)

kinetic data, nonisothermal reaction calorimetry

Hoffmann, Wilfried, Kang, Ying, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin ORCID: 0000-0002-1087-2692 (2007) Kinetic data by nonisothermal reaction calorimetry: a model-assisted calorimetric evaluation. Organic Process Research & Development, 11 (1). pp. 25-29. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op060144j)

microgels, affiliation characterisation

Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2007) Preparation, physico-chemical characterisation and applications of colloidal microgel particles. In: 233rd American Chemical Society National Meeting & Exposition, 25-29 Mar 2007, Chicago, Illinois USA. (Unpublished)

microgels, microgel applications, polymerisation, biomaterials

Thorne, Joanna B., Vine, George J. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2011) Microgel applications and commercial considerations. Colloid and Polymer Science, 289 (5-6). pp. 625-646. ISSN 0303-402X (Print), 1435-1536 (Online) (doi:https://doi.org/10.1007/s00396-010-2369-5)

microgels, phase transition, surface charge density, microgels, physicochemical properties

Gracia, Louise H. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2007) Preparation, properties and applications of colloidal microgels. In: Williams, Peter A., (ed.) Handbook of Industrial Water Soluble Polymers. Wiley-Blackwell, Oxford, pp. 268-297. ISBN 9781405132428 (doi:https://doi.org/10.1002/9780470988701.ch9)

monomer composition, co-polymer microgels, solid state Raman, NMR spectroscopy

Nur, H., Cornelius, V.J., Benée, L.S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Day, I.J. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2009) Semi-quantitative analysis of the monomer composition in co-polymer microgels using solid state Raman and NMR spectroscopy. Analyst, 134 (7). pp. 1366-1372. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B816792C)

n-isopropylacrylamide, particles, macromolecules, polymerization, chains

Woodward, Nicola C., Chowdhry, Babur Z., Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Leharne, Stephen A., Griffiths, P.C. ORCID: 0000-0002-6686-1271 and Winnington, Angie L. (2003) Calorimetric investigation of the influence of cross-linker concentration on the volume phase transition of poly(N-isopropylacrylamide) colloidal microgels. Langmuir, 19 (8). pp. 3202-3211. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la020881i)

nanoindentation, single crystals

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Dawson, N.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Predictive milling of pharmaceutical materials using nanoindentation of single crystals. Organic Process Research & Development, 8 (4). pp. 674-679. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op0300241)

particle size, mechanical properties, pharmaceutical crystals

Taylor, L.J., Papadopoulos, D.G., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Influence of particle size on mechanical properties of pharmaceutical crystals. Journal of Pharmacy and Pharmacology, 56 (S1). p. 37. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489302)

particle size, surface energy

Narishetty, S., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Papadopoulos, D., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Ticehurst, M.D. (2004) Influence of particle size on surface energy components of inhalation grade lactose. Journal of Pharmacy and Pharmacology, 56 (S1). p. 22. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

polyelectrolyte, colloidal microgels

Pinkrah, V.T., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Seidel, J., Chowdhry, B.Z. and Fern, G.R. (2003) Physicochemical properties of poly(N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Langmuir, 19 (3). pp. 585-590. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la026283l)

polyelectrolyte, microgels, DLS, electrophoretic mobility, pH and temperature responsive swelling

Nur, H., Pinkrah, V. T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Benée, L.S. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2009) Synthesis and properties of polyelectrolyte microgel particles. Advances in Colloid and Interface Science, 158 (1-2). pp. 15-20. ISSN 0001-8686 (doi:https://doi.org/10.1016/j.cis.2009.07.008)

polymeric particles

Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Thorne, Joanna B. (2010) Preparation, characterisation and application of smart polymeric particles. In: V Congress of Pharmacists of Serbia, 13-15 Oct 2010, Belgrade, Serbia. (Unpublished)

polymers, adsorption

Snowden, M. ORCID: 0000-0002-1087-2692 , Chowdhry, B. and Leharne, S. (1997) Good mixers. Chemistry in Britain, 33 (12). pp. 46-49. ISSN 0009-3106

polymorph spectroscopy

Moradiya, Hiren, Islam, Muhammad T., Woollam, Grahame R., Slipper, Ian J., Halsey, Sheelagh, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2013) Continuous cocrystallization for dissolution rate optimization of a poorly water-soluble drug. Crystal Growth & Design, 14 (1). pp. 189-198. ISSN 1528-7483 (Print), 1528-7505 (Online) (doi:https://doi.org/10.1021/cg401375a)

polymorphs, transformation, variable-temperature XRPD, caprolactam, extrudates, near-infrared spectroscopy, Polynorphism, drug delivery, crystals

Maniruzzaman, Mohammed, Islam, Muhammad T., Moradiya, Hiren G., Halsey, Sheelagh A., Slipper, Ian J., Chowdhry, Babur Z., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2014) Prediction of polymorphic transformations of paracetamol in solid dispersions. Journal of Pharmaceutical Sciences, 103 (6). pp. 1819-1828. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1002/jps.23992)

powder flow behaviour

Gururajan, B., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Mapping powder flow behaviour at different pharmaceutical processing stage. Journal of Pharmacy and Pharmacology, 57 (S1). S66-S66. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248604)

smart fabrics,

Majcen, Natasa, Snowden, Martin ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Cornelius, Victoria J. and Voncina, Bojana (2005) The development of smart fabrics. Journal of Pharmacy and Pharmacology, 57 (Suppl.). S58-S58. ISSN Online ISSN: 2042-7158

smart materials, nanoparticles, cross-linked polymers, microgel synthesis

Kausar, Nighat, Chowdhry, Babur Z. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2007) Microgels from smart polymers. In: Galaev, Igor and Mattiason, Bo, (eds.) Smart Polymers: applications in biotechnology and biomedecine. CRC Press, Boca Racon, FL, USA, pp. 137-176. ISBN 9780849391613

sodium deoxycholate, NaDC, human intestinal absorption, %HIA, hydrogels, flow-through cells, static diffusion cells, absorption, permeation

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

sodium dodecyl sulphate, colloidal microgels, high sensitivity differential scanning calorimetry, viscometry, turbidity, light scattering, sorption isotherm, conductivity

Woodward, Nicola C., Chowdhry, Babur Z., Leharne, Stephen A. and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2000) The interaction of sodium dodecyl sulphate with colloidal microgel particles. European Polymer Journal, 36 (7). pp. 1355-1364. ISSN 0014-3057 (doi:https://doi.org/10.1016/S0014-3057(99)00207-4)

solid dispersions, cationic drugs, anionic polymers, hot-melt extrusion (HME) technique

Maniruzzaman, Mohammed, Morgan, David J., Mendham, Andrew P., Pang, Jiayun ORCID: 0000-0003-0689-8440 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2012) Drug–polymer intermolecular interactions in hot-melt extruded solid dispersions. International Journal of Pharmaceutics, 443 (1-2). pp. 199-208. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2012.11.048)

thermodynamic considerations, microgel swelling behavior

Pinkrah, V.T., Beezer, A.E., Chowdry, B.Z., Gracia, L.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Thermodynamic considerations of microgel swelling behavior. Langmuir, 20 (20). pp. 8531-8536. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la035765+)

vasculitis, botryomycosis

Snowden, Martin ORCID: 0000-0002-1087-2692 , McAlindo, Timothy E. and Morosan, Cristian G (2006) Small vessel vasculitis in a patient with botryomycosis. Journal of Rheumatology, 33 (12). pp. 2545-2547. ISSN 0315-162X (Print), 1499-2752 (Online)

xylose, glycine, freeze-dried materials

Fei, D., Auffrett, A.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) The study of the reaction between xylose and glycine in freeze-dried materials. Journal of Pharmacy and Pharmacology, 56 (S1). S24-S24. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)