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Preparation, physico-chemical characterisation and applications of colloidal microgel particles

Preparation, physico-chemical characterisation and applications of colloidal microgel particles

Snowden, Martin J. (2007) Preparation, physico-chemical characterisation and applications of colloidal microgel particles. In: 233rd American Chemical Society National Meeting & Exposition, 25-29 Mar 2007, Chicago, Illinois USA. (Unpublished)

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Abstract

Colloidal microgel particles may be prepared by an emulsion polymerisation technique. It is often advantageous to prepare microgels from two or more monomers to confer different physico-chemical properties. The distribution of one monomer relative to another within a microgel structure may be determined by neutron scattering. Data will be presented for the distribution of butyl acrylate and N-isopropylacrylamide in a co-polymer microgel prepared from the two monomers. Further for a co-polymer of N-isopropylacrylamide and vinyl pyridine, Raman spectroscopy has been used to determine the concentration of vinyl pyridine in the microgel particles. The concentration of a given monomer in a microgel is often different to the starting concentration in the reaction mixture due to different reactivity ratios. Data will be shown that co-polymer microgels offer potential for drug delivery and the distribution and ratio of the two monomers can have a profound effect on their capacity to deliver drug molecules.

Item Type: Conference or Conference Paper (Paper)
Additional Information: [1] This paper was presented on 28 March 2007 at the 233rd ACS (American Chemical Society) National Meeting held from 25-29 March 2007 in Chicago, Illinois, USA. It was given within the Oral Nanoparticles: Synthesis, Passivation, Stabilization, and Functionalization Synthesis and Processing Session on 28 March 2008.
Uncontrolled Keywords: microgels, affiliation characterisation
Subjects: Q Science > Q Science (General)
Pre-2014 Departments: School of Science
Related URLs:
Last Modified: 14 Oct 2016 09:18
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/7233

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