Items where Greenwich Author is "Everett, Jeremy"
Said, Mohamed, Freire, Rafael, Cabreiro, Filipe, Serrano-Contreras, Jose Ivan, Thompson, Elinor P. ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy R.
(2025)
Phenotypic and metabonomics studies of FMOs in C. elegans and their roles in lifespan extension.
Metabolomics, 21 (6):170.
ISSN 1573-3882 (Print), 1573-3890 (Online)
(doi:10.1007/s11306-025-02367-4)
Said, Mohamed, Freire, Rafael, Cabreiro, Filipe, Serrano-Contreras, Jose Ivan, Thompson, Elinor P. ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy R.
(2025)
Phenotypic and metabonomics studies of FMOs in C. elegans and their roles in lifespan extension.
Metabolomics.
ISSN 1573-3882 (Print), 1573-3890 (Online)
(In Press)
Everett, Jeremy R., Karpe, Fredrik, Le Guennec, Adrien, Neville, Matt and Redfield, Christina (2025) Clinical and metabolic phenotypes of Oxford biobank subjects with variations in human flavin-containing monooxygenase 5 (FMO5). Metabolomics, 21:135. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:10.1007/s11306-025-02308-1)
Said, Mohamed, Ferrara, Bill T. ORCID: https://orcid.org/0000-0002-2163-4032, Aprodu, Andrea, Cabreiro, Filipe, Thompson, Elinor P.
ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy
(2024)
Transcriptional analysis of C. elegans fmos at different life stages and their roles in ageing.
Molecular Genetics and Genomics, 299:113.
ISSN 1617-4615 (Print), 1617-4623 (Online)
(doi:10.1007/s00438-024-02201-x)
Keohane, Patrick, Everett, Jeremy, Pereira, Rui, EVERETT, Jeremy, Blonquist, Traci and Mah, Eunice (2024) Supplementation of spermidine at 40 mg/day has minimal effects on circulating polyamines: an exploratory double-blind randomized controlled trial in older men. Nutrition Research, 132. ISSN 0271-5317 (Print), 1879-0739 (Online) (doi:10.1016/j.nutres.2024.09.012)
Hakalehto, Elias, Laatkainen, Reino, Pesola, Jouni, Dahlquist, Erik and Everett, Jeremy (2024) Chapter 3. Mixed strain fermentation and metabolomics for solving issues of bioproduction. In: Hakalehto, Elias, (ed.) Mixed Cultures in Industrial Bioprocesses. Advances in Biochemical Engineering/Biotechnology (ABE), 189 . Springer Cham, Berlin; Heidelberg, pp. 1-19. ISBN 978-3031735257; 978-3031735288; 978-3031735264 (doi:10.1007/10_2024_266)
Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Shephard, Elizabeth
(2022)
Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition.
Frontiers in Physiology, 13:859681.
pp. 1-13.
ISSN 1664-042X (Online)
(doi:10.3389/fphys.2022.859681)
Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2021)
Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines.
Metabolomics, 17 (12):104.
ISSN 1573-3882 (Print), 1573-3890 (Online)
(doi:10.1007/s11306-021-01852-w)
Said, Mohamed, Thompson, Elinor ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy
ORCID: https://orcid.org/0000-0003-1550-4482
(2021)
Modulation of ageing by genetic knock-out, phototherapy and drugs in the C. elegans worm.
In: Metabolism of Ageing, 06 - 08 Sep 2021, online.
(Unpublished)
Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .
Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2020)
Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines.
Metabolomics, 16 (4):51.
ISSN 1573-3882 (Print), 1573-3890 (Online)
(doi:10.1007/s11306-020-01674-2)
Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Shephard, Elizabeth A.
(2020)
Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine.
Drug Metabolism and Disposition, 48 (4).
ISSN 0090-9556 (Print), 1521-009X (Online)
(doi:10.1124/dmd.119.089995)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2019)
Pharmacometabonomics: the prediction of drug effects using metabolic profiling.
In: Barrett, James E., Page, Clive P. and Michel, Martin C., (eds.)
Concepts and Principles of Pharmacology: 100 Years of the Handbook of Experimental Pharmacology.
Handbook of Experimental Pharmacology, 260
.
Springer, Cham, Switzerland, pp. 263-300.
ISBN 978-3030353612
(doi:10.1007/164_2019_316)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K.
(2019)
A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis.
Trends in Pharmacological Sciences, 40 (10).
pp. 763-773.
ISSN 0165-6147 (Print), 1873-3735 (Online)
(doi:10.1016/j.tips.2019.08.004)
Said, Mohamed, Thompson, Elinor ORCID: https://orcid.org/0000-0002-6434-9290 and Everett, Jeremy
ORCID: https://orcid.org/0000-0003-1550-4482
(2019)
Metabolic ageing in the C. elegans worm and modulation by genetic knock-out, phototherapy and drugs.
In: UK C.elegans meeting, 16th September 2019, Imperial College London, Sir Alexander Fleming Building, Imperial College Rd, London, UK.
(Unpublished)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2018)
Applications of metabolic phenotyping in pharmaceutical research and development.
In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.)
The Handbook of Metabolic Phenotyping.
Elsevier, pp. 407-448.
ISBN 978-0128122938
Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2018)
Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice.
Frontiers in Molecular Biosciences, 5:28.
ISSN 2296-889X (Online)
(doi:10.3389/fmolb.2018.00028)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2017)
NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine.
Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3.
pp. 1-14.
ISSN 0079-6565 (Print), 1873-3301 (Online)
(doi:10.1016/j.pnmrs.2017.04.003)
Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2016)
The role of pharmacometabonomics in predicting drug pharmacokinetics.
International Journal of Pharmacokinetics, 1 (1).
pp. 5-8.
ISSN 2053-0846 (Print), 2053-0854 (Online)
(doi:10.4155/ipk-2016-0010)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2016)
From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine.
Frontiers in Pharmacology, 7:297.
ISSN 1663-9812
(doi:10.3389/fphar.2016.00297)
Bell, Andrew S., Bradley, Joseph, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Loesel, Jens, McLoughlin, David, Mills, James, Peakman, Marie-Claire, Sharp, Robert E., Williams, Christine and Zhu, Hongyao
(2016)
Plate-based diversity subset screening generation 2: An improved paradigm for high throughput screening of large compound files.
Molecular Diversity, 20 (4).
pp. 789-803.
ISSN 1381-1991 (Print), 1573-501X (Online)
(doi:10.1007/s11030-016-9692-9)
Sanchon-Lopez, Beatriz and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2016)
New methodology for known metabolite identification in metabonomics / metabolomics: topological metabolite identification carbon efficiency (tMICE).
Journal of Proteome Research, 15 (9).
pp. 3405-3419.
ISSN 1535-3893 (Print), 1535-3907 (Online)
(doi:10.1021/acs.jproteome.6b00631)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Sanchon Lopez, Beatriz
(2016)
New Approaches to NMR-Based Metabolite Identification.
In: 12th Annual Conference of the Metabolomics Society, 27 June 2016 - 30 June 2016, Dublin, Eire.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill
(2016)
A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments.
Computational and Structural Biotechnology Journal, 14.
pp. 135-153.
ISSN 2001-0370 (Print), 2001-0370 (Online)
(doi:10.1016/j.csbj.2016.02.005)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Lindon, John and Nicholson, Jeremy
(2016)
Pharmacometabonomics and predictive metabonomics: New tools for personalised medicine.
In: Nicholson, Jeremy, Darzi, A, Lindon, John and Holmes, Elaine, (eds.)
Metabolic Phenotyping in Personalized and Public Healthcare.
Elsevier Science Publishing Co Inc, pp. 137-165.
ISBN 9780128003442
(doi:10.1016/B978-0-12-800344-2.00006-9)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Harris, Robin, Lindon, John and Wilson, Ian (eds.)
(2015)
NMR in pharmaceutical sciences.
eMagRes Books
.
Wiley.
ISBN 9781118997666
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
Academic drug discovery: Current status and prospects.
Expert Opinion on Drug Discovery, 10 (9).
pp. 937-944.
ISSN 1746-0441 (Print), 1746-045X (Online)
(doi:10.1517/17460441.2015.1059816)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
From metabonomics to pharmacometabonomics: Mice, men and microbiota.
In: Neuviemes Journees Scientifiques du Reseau Francais de Metabolomique et Fluxomique, 9 -11 June 2015, Lille, France.
(Unpublished)
Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A.
(2015)
The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.
Biochemical Pharmacology, 96 (3).
pp. 267-277.
ISSN 0006-2952
(doi:10.1016/j.bcp.2015.05.013)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
Pharmacogenomics and pharmacometabonomics for personalised medicine.
In: FOCUS 2015: National Meeting of the Association for Clinical Biochemistry & Laboratory Medicine, 8-11 June 2015, Cardiff, Wales.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
Pharmacometabonomics in humans: a new tool for personalized medicine.
Pharmacogenomics, 16 (7).
pp. 737-754.
ISSN 1462-2416
(doi:10.2217/PGS.15.20)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
Drug discovery and development: the role of NMR.
eMagRes.
John Wiley & Sons, Ltd., London, UK, pp. 137-150.
ISBN 9780470034590
(doi:10.1002/9780470034590.emrstm1389)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency.
Computational and Structural Biotechnology Journal, 13.
pp. 131-144.
ISSN 2001-0370
(doi:10.1016/j.csbj.2015.01.002)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
From metabonomics to pharmacometabonomics: An NMR-based excursion from metabolite profiling to precision medicine.
In: Invited Lecture at Institute of Food Research, 19 March 2015, Institute of Food Research, Norwich, UK.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2015)
From metabonomics to pharmacometabonomics: Mice, men and m
microbiota.
In: University College London Spring Seminars, 25 February 2015, University College London, UK.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2014)
Pharmacometabonomics: An important new paradigm for precision medicine.
In: Metabomeeting 2014, 10-12 Sep 2014, The Royal Institution, London, UK.
(Unpublished)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2014)
Pharmacometabonomics: The ability to use pre-dose metabolite profiles to predict drug responses.
In: EMBL Practical Course: Metabolomics Bioinformatics for Life Scientists, 17- 21 March, 2014, Hinxton Genome Campus, UK.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2013)
New approaches to personalised medicine via pharmacometabonomics.
In: Lifescience R&D Big Data Leaders Forum, 3-5 Dec 2013, Basel, Switzerland.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2013)
New approaches to the design of large screening files for lead discovery.
In: Lifescience R&D Big Data Leaders Forum, 3-5 Dec 2013, Basel, Switzerland.
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Loo, Ruey Leng and Pullen, Francis S.
(2013)
Pharmacometabonomics and personalized medicine.
Annals of Clinical Biochemistry, 50 (6).
pp. 523-545.
ISSN 0004-5632 (Print), 1758-1001 (Online)
(doi:10.1177/0004563213497929)
Bell, Andrew S., Bradley, Joseph, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P.
(2013)
Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file.
Molecular Diversity, 17 (2).
pp. 319-335.
ISSN 1381-1991 (Print), 1573-501X (Online)
(doi:10.1007/s11030-013-9438-x)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2013)
Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November
2012, Nanjing, China.
Expert Opinion on Drug Discovery, 8 (3).
pp. 357-361.
ISSN 1746-0441 (Print), 1746-045X (Online)
(doi:10.1517/17460441.2013.762353)
Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P.
(2012)
Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy.
Journal of Chemical Information and Modeling, 52 (11).
pp. 2937-2949.
ISSN 1549-9596 (Print), 1549-960X (Online)
(doi:10.1021/ci300372a)
Cunningham, Katharine, Claus, Sandrine P., Lindon, John C., Holmes, Elaine, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Nicholson, Jeremy K. and Coen, Muireann
(2012)
Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response.
Journal of Proteome Research, 11 (9).
pp. 4630-4642.
ISSN 1535-3893 (Print), 1535-3907 (Online)
(doi:10.1021/pr300430u)
Nicholson, Jeremy K., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Lindon, John C.
(2012)
Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy.
Expert Opinion on Drug Metabolism & Toxicology, 8 (2).
pp. 135-139.
ISSN 1742-5255
(doi:10.1517/17425255.2012.646987)
Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2006)
Metabolic applications in clinical pharmaceutical R&D.
In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.)
The Handbook of Metabonomics and Metabolomics.
Elsevier, Amsterdam, The Netherlands, pp. 279-287.
ISBN 9780444528414
Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K.
(2006)
Hepatotoxin-induced hypertyrosinemia and its toxicological significance.
Archives of Toxicology, 81 (3).
pp. 201-210.
ISSN 0340-5761 (Print), 1432-0738 (Online)
(doi:10.1007/s00204-006-0136-7)
Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 and Nicholson, Jeremy K.
(2006)
Pharmaco-metabonomic phenotyping and personalized drug treatment.
Nature, 440 (7087).
pp. 1073-1077.
ISSN 0028-0836 (Print), 1476-4687 (Online)
(doi:10.1038/nature04648)
Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K.
(2006)
An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.
Journal of Proteome Research, 5 (10).
pp. 2675-2684.
ISSN 1535-3893 (Print), 1535-3907 (Online)
(doi:10.1021/pr0601584)
Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482
(2000)
Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids.
Concepts in Magnetic Resonance, 12 (5).
pp. 289-320.
ISSN 1552-5023 (online)
(doi:10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)
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