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Access to procedural memories after one year: evidence for robust memory consolidation in Tourette syndrome

Access to procedural memories after one year: evidence for robust memory consolidation in Tourette syndrome

Toth-Faber, E, Tarnok, Z, Takacs, A, Janacsek, Karolina ORCID: 0000-0001-7829-8220 and Nemeth, D (2021) Access to procedural memories after one year: evidence for robust memory consolidation in Tourette syndrome. Frontiers in Human Neuroscience, 15:715254. ISSN 1662-5161 (Print), 1662-5161 (Online) (doi:https://doi.org/10.3389/fnhum.2021.715254)

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Abstract

Tourette syndrome is a childhood-onset neurodevelopmental disorder characterized by motor and vocal tics. On the neural level, tics are thought to be related to the disturbances of the cortico-basal ganglia-thalamo-cortical loops, which also play an important role in procedural learning. Several studies have investigated the acquisition of procedural information and the access to established procedural information in TS. Based on these, the notion of procedural hyperfunctioning, i.e., enhanced procedural learning, has been proposed. However, one neglected area is the retention of acquired procedural information, especially following a long-term offline period. Here, we investigated the 5-hour and 1-year consolidation of two aspects of procedural memory, namely serial-order and probability-based information. Nineteen children with TS between the ages of 10 and 15 as well as 19 typically developing gender- and age-matched controls were tested on a visuomotor four-choice reaction time task that enables the simultaneous assessment of the two aspects. They were retested on the same task 5 hours and 1 year later without any practice in the offline periods. Both groups successfully acquired and retained the probability-based information both when tested 5 hours and then 1 year later, with comparable performance between the TS and control groups. Children with TS did not acquire the serial-order information during the learning phase; hence, retention could not be reliably tested. Our study showed evidence for short-term and long-term retention of one aspect of procedural memory, namely probability-based information in TS, whereas learning of serial-order information might be impaired in this disorder.

Item Type: Article
Uncontrolled Keywords: Tourette syndrome, neurodevelopmental disorders, procedural memory, statistical learning, sequence learning, consolidation
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Faculty / School / Research Centre / Research Group: Faculty of Education, Health & Human Sciences
Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development
Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Thinking and Learning
Related URLs:
Last Modified: 04 Oct 2021 11:29
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
Selected for REF2021: None
URI: http://gala.gre.ac.uk/id/eprint/34007

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