Nicolucci, A., Balducci, S., Cardelli, P., Cavallo, S., Fallucci, S., Bazuro, A., Simonelli, P., Iacobini, C., Zanuso, S. and Pugliese, G. (2012) Relationship of exercise volume to improvements of quality of life with supervised exercise training in patients with type 2 diabetes in a randomised controlled trial: the Italian Diabetes and Exercise Study (IDES). Diabetologia, 55 (3). pp. 579-588. ISSN 0012-186X (Print), 1432-0428 (Online) (doi:10.1007/s00125-011-2425-9)

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Abstract

A positive impact of exercise intervention programmes on quality of life (QoL) may be important for long-term patient compliance to exercise recommendations. We have previously shown that QoL improves significantly with supervised exercise, whereas it worsens with counselling alone, in patients with type 2 diabetes from the Italian Diabetes and Exercise Study (IDES). Here, we report data on the relationship between changes in QoL and volume of physical activity/exercise in these individuals. Methods This multicentre parallel randomised controlled, open-label, trial enrolled sedentary patients with type 2 diabetes (n0606 of 691 eligible) in 22 outpatient diabetes clinics.
Patients were randomised by centre, age and diabetes reatment using a permuted-block design to twice-a-week supervised aerobic and resistance training plus exercise counselling (exercise group) versus counselling alone (control group) for 12 months. Health-related QoL was ssessed by the 36-Item Short Form (SF-36) Health Survey. Results In the exercise group (n0268 of 303 randomised), there was a trend for increasing QoL with increasing exercise volume, with significant improvement of the hysical component summary (PCS) measure only above 17.5 metabolic equivalents h−1 week −1 and a clear volume-relationship for the mental component summary (MCS) measure. A relationship with volume of physical activity also was observed in the control group (n0260 of 303 randomised), despite overall deterioration of all scores. Independent correlates of improvements in both PCS and MCS were exercise volume, study arm and, inversely, baseline score. Conclusions/interpretation This large trial shows a relationship between changes in physical and mental health-related QoL measures and volume of physical activity/exercise, with supervised exercise training also providing volume independent benefits.

Item Type:	Article
Uncontrolled Keywords:	exercise, physical activity, quality of life, type 2 diabetes
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Related URLs:	Publisher
Last Modified:	09 Oct 2021 04:46
URI:	http://gala.gre.ac.uk/id/eprint/7343

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