Everett, Jeremy ORCID: https://orcid.org/0000-0003-1550-4482 (2006) Metabolic applications in clinical pharmaceutical R&D. In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.) The Handbook of Metabonomics and Metabolomics. Elsevier, Amsterdam, The Netherlands, pp. 279-287. ISBN 9780444528414

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Abstract

Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

The Chapter "Metabolic applications in clinical pharmaceutical R&D" covers the various clinical applications of metabonomics in pharmaceutical research and development.

Item Type:	Book Section
Additional Information:	[1] Chapter 10.
Uncontrolled Keywords:	metabonomics
Subjects:	Q Science > QH Natural history > QH301 Biology R Medicine > RS Pharmacy and materia medica
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science > School of Science (SCI) Faculty of Engineering & Science
Related URLs:	Publisher Publisher Organisation
Last Modified:	19 Nov 2024 14:02
URI:	http://gala.gre.ac.uk/id/eprint/5266

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