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Effect of a multi-ingredient post-workout dietary supplement on body composition and muscle strength – a randomized controlled trial

Effect of a multi-ingredient post-workout dietary supplement on body composition and muscle strength – a randomized controlled trial

Puente-Fernández, Joel ORCID logoORCID: https://orcid.org/0000-0002-4477-8637, Larumbe-Zabala, Eneko, Roberts, Justin and Naclerio, Fernando ORCID logoORCID: https://orcid.org/0000-0001-7405-4894 (2025) Effect of a multi-ingredient post-workout dietary supplement on body composition and muscle strength – a randomized controlled trial. Journal of Dietary Supplements. ISSN 1939-0211 (Print), 1939-022X (Online) (doi:10.1080/19390211.2025.2488811)

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Abstract

The aim of the current parallel randomized controlled trial was to compare the effects of ingesting a dietary supplement admixture providing carbohydrates, leucine-fortified whey protein, creatine, β-hydroxy-β-methylbutyrate, and vitamin D3 (Master Recovery 1:1, Crown Sport Nutrition, Spain), versus an isoenergetic carbohydrate-only comparator on body composition, muscle thickness, muscle strength, and performance over a 6-week resistance training program, performed three times per week, in aging, physically active individuals. Twenty participants (10 peri- and post-menopausal females and 10 males) ­completed the study after being randomly assigned to one of the following groups: post-workout multi-ingredient (PWS: n = 10, 52.0 ± 5 years, body mass 82.0 ± 18.0 kg) or a comparator (COM: n = 10, 51 ± 3 years, body mass 85.9 ± 17.0 kg). Treatment consisted of ingesting 60.0 g of the assigned supplement immediately after each workout. Compared to baseline, only PWS increased fat-free mass (+1.34 ± 1.2 kg, p = 0.003), reduced fat mass (–1.09 ± 0.7 kg, p < 0.001), waist circumference (–2.5 ± 1.8 cm, p < 0.001), and waist-to-hip ratio (–0.03 ± 0.03 cm, p = 0.007). At post-intervention, waist circumference reduction was different between groups (p = 0.02, d = 1.19). Both treatments similarly improved vastus lateralis and elbow flexor thickness, medicine ball throw, and endurance performance. Although countermovement jump improved for both treatments, the PWS group showed a significantly higher performance increase compared to COM (p < 0.01, d = 1.47). Compared to ingesting carbohydrates only, the use of a targeted multi-ingredient promoted noticeable body composition outcomes and better vertical jump improvements with no further effects on hypertrophy, upper body, and endurance performance. The study was registered as a clinical trial at ClinicalTrials.gov (NCT05769088).

Item Type: Article
Uncontrolled Keywords: aging, body composition, creatine, dietary supplement, muscle, muscle strength, resistance training, whey protein
Subjects: R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Faculty / School / Research Centre / Research Group: Faculty of Education, Health & Human Sciences
Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified: 14 Apr 2025 09:29
URI: http://gala.gre.ac.uk/id/eprint/50204

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