Evans, Jules, Aixalà, Marc, Anderson, Brian T., Brennan, William, Bremler, Rebecka, Breeksema, Joost J., Burback, Lisa, Calder, Abigail E., Carhart‐Harris, Robin L., Cheung, Katherine, Devenot, Neşe, Gorman, Ingmar, Greń, Jakub, Hendricks, Peter S., Holoyda, Brian, Jacobs, Edward, Krecké, Joy, Kruger, Daniel J., Luke, David ORCID: https://orcid.org/0000-0003-2141-2453, Majić, Tomislav, McGuire, Amy L., Mehtani, Nicky J., Mathai, David S., Nash, Kristin, Noorani, Tehseen, Palitsky, Roman, Robinson, Oliver ORCID: https://orcid.org/0000-0002-6758-2223, Simonsson, Otto, Stahre, Elin, van Elk, Michiel and Yaden, David B. (2025) On minimizing risk and harm in the use of psychedelics. Psychiatric Research & Clinical Practice. ISSN 2575-5609 (Online) (doi:10.1176/appi.prcp.20240128)

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Abstract

Objective:
This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net.
Methods:
A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety.
Results:
The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors of those harms, and the most effective way to treat those harms. They also call for better support for those experiencing post‐psychedelic difficulties, including better online information, peer support groups, affordable therapy, and psychiatric consultation and medication. Finally, the authors call for better funding to create a psychedelic safety net, and suggest psychedelic philanthropists, investors and companies could commit 1% of their investment in psychedelics into supporting safety measures such as research and support services.
Conclusions:
The authors identify several practical steps to create a better psychedelic safety net and call for more funding to psychedelic safety measures such as research and support services.
Relevance to clinical practice:
The authors outline important gaps in our knowledge around the safety and risk profile of psychedelic medicines and identify practical steps forward for researchers and clinical practitioners to make this promising field safer.

Item Type:	Article
Additional Information:	Submitted by DL 14.2.25. Edited by RM 18.2.25.
Uncontrolled Keywords:	psychedelic, harm reduction, risk, mental health
Subjects:	H Social Sciences > H Social Sciences (General) H Social Sciences > HV Social pathology. Social and public welfare R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Mental Health
Last Modified:	18 Feb 2025 16:39
URI:	http://gala.gre.ac.uk/id/eprint/49769

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