Arribas Lopez, Elena ORCID: https://orcid.org/0000-0003-1512-7154, Zand Fard, Nazanin ORCID: https://orcid.org/0000-0003-2058-2354, Ojo, Omorogieva ORCID: https://orcid.org/0000-0003-0071-3652 and Kochhar, Tony (2025) A systematic review and meta-analysis of the effect of zinc on wound healing. British Medical Journal (The BMJ). ISSN 1759-2151 (Print), 0959-8138 (Online) (doi:10.1136/bmjnph-2024-000952)

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Abstract

In times of metabolic stress, the demand for nutrients increases, which is essential to prevent delayed healing and development of chronic wounds. This study presents a systematic review and meta-analysis examining the effect of zinc treatment on wound healing. The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and included data from four electronic data bases. Five clinical trials met the inclusion criteria. The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03). Given the limitations of the included studies, a Grading of Recommendations, Assessment, Development and Evaluation assessment indicated a moderate quality of evidence.

Item Type:	Article
Uncontrolled Keywords:	zinc sulfate, zinc oxide, ulcers, inflammation, tissue granulation, re-epithelialization, wound healing
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General)
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > School of Health Sciences (HEA) Faculty of Engineering & Science Faculty of Engineering & Science > Natural Resources Institute Faculty of Engineering & Science > School of Science (SCI)
Last Modified:	06 Feb 2025 11:10
URI:	http://gala.gre.ac.uk/id/eprint/49523

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