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Response trajectories and temporal trends of viloxazine treatment for young people with ADHD

Response trajectories and temporal trends of viloxazine treatment for young people with ADHD

Yu, Chia-Ling, Kao, Yu-Chen, Thompson, Trevor ORCID logoORCID: https://orcid.org/0000-0001-9880-782X, Stubbs, Brendon, Tseng, Ping-Tao, Hsu, Chih-Wei, Yang, Fu-Chi, Tu, Yu-Kang, Hsu, Tien-Wei and Liang, Chih-Sung (2024) Response trajectories and temporal trends of viloxazine treatment for young people with ADHD. JAMA Network Open, 7 (11):e2445885. ISSN 2574-3805 (Online) (doi:10.1001/jamanetworkopen.2024.45885)

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Abstract

Importance: Viloxazine is a novel nonstimulant medication approved for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Objectives: To investigate the whether viloxazine is associated with effective and acceptable outcomes when treating children and adolescents with ADHD and to evaluate these outcomes’ associations with viloxazine doses and duration of treatment.
Data Sources: The MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, PsycINFO, and ClinicalTrial.gov databases were searched from database inception to June 23, 2024.
Study Selection: Two reviewers independently screened for double-blind, fixed-dose randomized clinical trials (RCTs) that compared viloxazine with placebo for pediatric patients with ADHD.
Data Extraction and Synthesis: The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guideline. Data extraction was completed independently by 2 authors and cross-checked for errors. Random-effects pairwise and dose

Item Type: Article
Uncontrolled Keywords: ADHD, viloxazine, young people, meta-analysis
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RS Pharmacy and materia medica
Faculty / School / Research Centre / Research Group: Faculty of Education, Health & Human Sciences
Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development
Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Chronic Illness and Ageing
Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified: 27 Nov 2024 16:27
URI: http://gala.gre.ac.uk/id/eprint/48705

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