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Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study

Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study

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Gong, Chao, Zeng, Pei ORCID logoORCID: https://orcid.org/0000-0001-5214-2973, Lian, Beibei, Li, Jiawei, Liu, Jiahao ORCID logoORCID: https://orcid.org/0000-0001-5214-2973, Liu, Yuanyuan, Fang, Liya, Tian, Huiling, Wang, Luchuan, Jiang, Zhimei, Guo, Jin and Zhou, Shaobo ORCID logoORCID: https://orcid.org/0000-0001-5214-2973 (2024) Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study. BMC Pediatric. ISSN 1471-2431 (Online) (In Press)

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Abstract

Objective: This study aimed to explore the characteristics of risk factors in children with cerebral palsy (CP), focusing on how individual risk factors and the number of risk factors affect CP classification, GMFCS level, and comorbidities.
Methods: Medical records of children with CP hospitalized between 2015 and 2023 were reviewed. The effects of nine risk factors, including hyperbilirubinemia, asphyxia, and hypoxic-ischemic encephalopathy (HIE), on CP classification, GMFCS level, and comorbidities were analyzed.
Results: Among 536 children with CP, 476 (88.8%) presented with identifiable risk factors, with preterm birth and/or low birth weight being the most prevalent (243 cases, 45.3%). A combination of two risk factors was the most common scenario (147 cases, 27.4%). Findings revealed associations between specific risk factors and CP characteristics: neonatal seizures correlated with epilepsy, while HIE and hyperbilirubinemia were linked to intellectual disability. Asphyxia was associated with higher GMFCS.

Item Type: Article
Uncontrolled Keywords: cerebral palsy, classification, GMFCS, intellectual disability, epilepsy, hearing impairment, retrospective study, Northeast China
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > School of Science (SCI)
Related URLs:
Last Modified: 13 Nov 2024 16:38
URI: http://gala.gre.ac.uk/id/eprint/48621

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