Ojo, Omorogieva ORCID: 0000-0003-0071-3652 and Elliott, Helen ORCID: 0000-0002-8798-1037 (2024) The role of prebiotics in gastrointestinal health: a systematic review. Gastrointestinal Nursing, 22 (5). pp. 242-249. ISSN 1479-5248 (Print), 2052-2835 (Online) (doi:https://doi.org/10.12968/gasn.2023.0040)

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Abstract

Background: Many chronic conditions in humans, including inflammatory bowel disease and irritable bowel syndrome, have been linked to an imbalance in the gut microbial ecosystem. The maintenance of healthy gut microbiota involving the use of prebiotics may contribute to eubiosis, which could be useful in promoting gastrointestinal health. This systemic review aims to examine the role of prebiotics in gastrointestinal health.
Method: The systematic review was conducted based on the PRISMA framework. Searches were carried out in electronic databases including Health Sciences Research Databases, EMBASE and the reference list of articles. The PICO tool was used to develop the search terms and the results of the searches were screened for eligibility based on inclusion and the exclusion criteria.
Results: Seven randomised controlled studies were included in the systematic review. Following the review of the results of the studies included, three distinct areas were identified.
Conclusions: This systematic review has demonstrated that prebiotics are effective in promoting the relative abundance of Bifidobacterium and gastrointestinal health with minimal discomfort, although the type and amount of prebiotics are important factors.

Item Type:	Article
Uncontrolled Keywords:	bifidobacterium, gastrointestinal health, gut microbiota dysbiosis, prebiotics, short chain fatty acids
Subjects:	R Medicine > R Medicine (General) R Medicine > RC Internal medicine
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Chronic Illness and Ageing Faculty of Education, Health & Human Sciences > School of Health Sciences (HEA)
Last Modified:	13 Aug 2024 13:33
URI:	http://gala.gre.ac.uk/id/eprint/47647

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