Lam, Kevin ORCID: https://orcid.org/0000-0003-1481-9212, Leech, Matthew and Lennox, Alastair (2021) Electrochemistry in natural product synthesis. In: Lutz, Ackerman, (ed.) Electrochemistry in Organic Synthesis. Science of Synthesis . Thieme Verlagsgruppe, Stuttgart, New York, Delhi, Rio. ISBN 3132442127; 978-3132442122 (doi:10.1055/sos-SD-236-00280)

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Abstract

The multistep synthesis of natural products has historically served as a useful and informative platform for showcasing the best, state-of-the-art synthetic methodologies and technologies. Over the last several decades, electrochemistry has proved itself to be a useful tool for conducting redox reactions, primarily due to its unique ability to selectively apply any oxidizing or reducing potential to a sufficiently conductive reaction solution.1–6 In addition, electrochemical redox reactions are readily scaled and can be more sustainable than competing strategies based on conventional redox reagents. In this chapter, we summarize where electrochemistry has been used in the synthesis of natural products. The chapter is organized by the reaction-type of the electrochemical step. We do not include derivatives, analogues or unnatural cores as part of the collection, nor are formal syntheses included. As new electrochemical methodologies are discovered and developed, we expect that more examples will include electrochemical steps as part of their synthesis.

Item Type:	Book Section
Uncontrolled Keywords:	electrosynthesis; natural product
Subjects:	Q Science > QC Physics Q Science > QD Chemistry
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	https://www.thieme-connect.de/products/e...
Last Modified:	23 Jun 2022 09:27
URI:	http://gala.gre.ac.uk/id/eprint/36284

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