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GeneXpert MTB/RIF version G4 for identification of Rifampin-resistant tuberculosis in a programmatic setting

GeneXpert MTB/RIF version G4 for identification of Rifampin-resistant tuberculosis in a programmatic setting

Osman, Muhammad ORCID: 0000-0003-3818-9729, Simpson, John A., Caldwell, Judy, Bosman, Marlein and Nicol, Mark P. (2014) GeneXpert MTB/RIF version G4 for identification of Rifampin-resistant tuberculosis in a programmatic setting. Journal of Clinical Microbiology, 52 (2). pp. 635-637. ISSN 0095-1137 (Print), 1098-660X (Online) (doi:https://doi.org/10.1128/JCM.02517-13)

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Abstract

A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin resistance as 98% (95% confidence interval [CI], 97 to 99), based on results from earlier test versions. The measured positive predictive value of the new generation test from programmatic implementation in Cape Town, South Africa, was 99.5% (95% CI, 98.5 to 100), confirming excellent specificity.

Item Type: Article
Uncontrolled Keywords: Xpert MTB/RIF; Rifampin-resistant; DR-TB programme
Subjects: Q Science > QA Mathematics > QA76 Computer software
R Medicine > RS Pharmacy and materia medica
Faculty / School / Research Centre / Research Group: Faculty of Education, Health & Human Sciences
Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified: 22 Mar 2022 10:46
URI: http://gala.gre.ac.uk/id/eprint/35535

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