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Regioselective electrochemical cyclobutanol ring expansion to 1-tetralones

Regioselective electrochemical cyclobutanol ring expansion to 1-tetralones

Petti, Alessia, Natho, Philipp, Lam, Kevin ORCID: 0000-0003-1481-9212 and Parsons, Philip J. (2020) Regioselective electrochemical cyclobutanol ring expansion to 1-tetralones. European Journal of Organic Chemistry, 2021 (5). pp. 854-858. ISSN 1434-193X (Print), 1099-0690 (Online) (doi:https://doi.org/10.1002/ejoc.202001535)

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Abstract

A mild electrochemical method for the regioselective preparation of 1‐tetralones under environmentally friendly conditions from readily available cyclobutanols was developed. A series of aromatic and heteroaromatic 1‐tetralones was accessed through ring expansion of the functionalized cyclobutanols via electrochemical generation of alkoxy radicals and intramolecular cyclization.

Item Type: Article
Uncontrolled Keywords: radials, electrosynthesis, electrochemistry, tetralone
Subjects: Q Science > Q Science (General)
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > School of Science (SCI)
Last Modified: 17 Mar 2021 10:15
URI: http://gala.gre.ac.uk/id/eprint/30574

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