Ojo, Omorogieva ORCID: 0000-0003-0071-3652 , Feng, Qianqian, Ojo, Osarhumwese Osaretin and Wang, Xiaohua (2020) Dietary Fibre, Gut Microbiota Dysbiosis and Type 2 Diabetes. In: The 1st International Electronic Conference on Nutrients - Nutritional and Microbiota Effects on Chronic Disease; Session: Interrelationships among microbiota, poor nutrition choices, and chronic disease. Special Issue . MDPI, Basel, Switzerland, pp. 1-4. ISSN 2072-6643 (doi:https://doi.org/10.3390/IECN2020-06986)

Preview

PDF (Publisher's Proof - Open Access) 30056 OJO_Dietary_Fibre_Gut_Microbiota_Dysbiosis_(OA)_2020.pdf - Published Version Available under License Creative Commons Attribution. Download (328kB) | Preview

Abstract

Background:
Diabetes prevalence is on the increase globally and its impact on those with the condition in terms of acute and chronic complications can be profound. People with type 2 diabetes constitute the majority of those with diabetes and the risk factors include obesity, lifestyle and gut microbiota dysbiosis. Poor dietary intake has been reported to influence the community of gut microbiome. Therefore, higher intake of dietary fibre may alter the environment in the gut and promote microbial growth and proliferation.

Aim:
This is a systematic review and meta-analysis which examined the effect of dietary fibre on gut microbiota in patients with type 2 diabetes. Method: This review was conducted in line with the PRISMA framework. Databases were searched for relevant articles which were screened based on inclusion and exclusion criteria. Results: Nine articles which met the inclusion criteria were selected for the systematic review and meta-analysis. High dietary intake significantly improved (p < 0.05) the abundance of Bifidobacterium, total SCFAs and HbA1c.

Discussion:
The promotion of SCFA producers in greater diversity and abundance by dietary fibre may have resulted in improvement in glycated haemoglobin, partly due to increased GLP–1 production. Conclusion: Consumption of high dietary fibre has significant (p < 0.05) effect on Bifidobacterium, total SCFAs and HbA1c, but not (p > 0.05) on propionic, butyric, and acetic acid, fasting blood glucose and HOMAR–IR.

Item Type:	Conference Proceedings
Title of Proceedings:	The 1st International Electronic Conference on Nutrients - Nutritional and Microbiota Effects on Chronic Disease; Session: Interrelationships among microbiota, poor nutrition choices, and chronic disease
Additional Information:	© 2020 by the authors. Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Uncontrolled Keywords:	type 2 diabetes; dietary fibre; gut microbiota; dysbiosis; short chain fatty acids; glycated haemoglobin; fasting blood glucose; adverse events
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Chronic Illness and Ageing Faculty of Education, Health & Human Sciences > School of Health Sciences (HEA)
Related URLs:	Publisher https://sciforum.net/event/IECN2020#sect...
Last Modified:	08 Oct 2021 09:07
URI:	http://gala.gre.ac.uk/id/eprint/30056

Actions (login required)

View Item

Downloads