Hou, Yunying, Zhang, Dandan, Zhu, Jifang, Zhao, Xin, Lu, Minxia, Wu, Qing, Ojo, Omorogieva ORCID: https://orcid.org/0000-0003-0071-3652, Wang, Xiaohua and Zhang, Yonghong (2021) Short report: depression and anxiety symptoms as predictors of adverse cardiovascular events in Chinese patients after percutaneous coronary intervention. Psychology, Health and Medicine., 26 (9). pp. 1126-1133. ISSN 1354-8506 (Print), 1465-3966 (Online) (doi:10.1080/13548506.2020.1837388)

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Abstract

Depression and anxiety often co-occur in coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI). This study was conducted to examine the predictive value of depression, anxiety, and their combination on the prognosis of Chinese PCI patients. A multicenter prospective study was undertaken with a sample of 309 primary PCI patients. The Hospital Anxiety and Depression Scale (HADS) was completed at baseline to assess anxiety and depression symptoms. Major adverse cardiovascular events (MACEs) were recorded for 12 months after PCI . Days from baseline to the first MACE was the outcome variable. MACEs occurred in 26 (8.4%) patients. After adjustments for socio-demographic and clinical characteristics, a Cox proportional hazards regression model revealed that depression (HR = 2.70, 95% confidence interval [CI] 1.22–5.95; p =.014) and anxiety (HR = 2.56, 95% CI 1.18–5.54; p =.017) symptoms were independent predictors of MACEs. A sub-analysis showed that the cumulative event-free survival curves did not differ among depressed and anxious patients and depressed but non-anxious patients (Log Rank p =.52). In conclusion, depression is associated with an increased risk for MACEs post-PCI, independent of anxiety. Although anxiety is associated with MACEs, it has no additional predictive value when co-occurring with depression.

Item Type:	Article
Uncontrolled Keywords:	Coronary artery disease, depression, anxiety, percutaneous coronary intervention, major adverse cardiovascular events
Subjects:	B Philosophy. Psychology. Religion > BF Psychology R Medicine > RD Surgery R Medicine > RT Nursing
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Chronic Illness and Ageing Faculty of Education, Health & Human Sciences > School of Health Sciences (HEA)
Related URLs:	Publisher http://pubmed.ncbi.nlm.nih.gov/33073611/
Last Modified:	24 Jan 2022 10:58
URI:	http://gala.gre.ac.uk/id/eprint/29966

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