Oluwaniyi, Titilope Ruth, Alvarez, Jose-Luis, Regina, Keith and Amorim, Amanda R. ORCID: https://orcid.org/0000-0003-2780-0350 (2020) Impact of the lipid-based nutrient supplements on prevention and treatment of childhood moderate undernutrition. International Journal of Food, Nutrition and Public Health (11):1/2. pp. 1-25. ISSN 2042-5988 (Print), 2042-5996 (Online)

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Abstract

Purpose:
This review aims at assessing the effectiveness of LNS interventions for prevention and/or treatment of moderate acute malnutrition (MAM), stunting and other anthropometric indicators for undernutrition in children younger than 5 years.

Methodology:
Eighteen clinical trials on LNS (soybased or milk-based) supplementation in children were compared with habitual diet/control or corn-soy blend (CSB). Mean changes in height for age (HAZ), weight for age (WAZ) and weight for height z-scores (WHZ) were assessed as primary outcomes. The secondary outcomes included: weight gain, height, mid upper arm circumference (MUAC), recovery from MAM, occurrence of fever, diarrhoea and cough.

Findings:
The pooled estimate revealed a statistically significant increase in WAZ (weighted mean difference [WMD] =0.09; 95%CI= 0.02, 0.15; p=0.01), WHZ (WMD=0.14; 95%CI= 0.01, 0.26; p=0.000) and improved recovery from MAM (Risk Ratio [RR] = 1.37; 95%CI= 1.14, 1.65; p=0.000) in children receiving LNS compared with control or CBS. No significant effect was observed in HAZ (WMD=0.00;95%CI=-0.02,0.03: p=0.578). Children fed with milk-based LNS (RR=1.68; 95%CI=1.17, 2.39; p=0.005) were more likely to recover significantly from MAM when compared with CSB.

Conclusion:
Although there is evidence that LNS yield better nutritional outcomes than CSB and control, it is impossible to conclude that the milk-based LNS are superior to soy-based LNS and whether age and duration of intervention significantly affect the effectiveness of LNS on childhood undernutrition. Further research is required before these products can be recommended at scale.

Item Type:	Article
Uncontrolled Keywords:	Lipid-based nutrient supplements; undernutrition; CMAM; childhood
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM) Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development Faculty of Education, Health & Human Sciences > Institute for Lifecourse Development > Centre for Chronic Illness and Ageing
Related URLs:	Publisher
Last Modified:	26 Mar 2020 18:50
URI:	http://gala.gre.ac.uk/id/eprint/27438

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