Cascade aza-Prins reactions
Cuprova, Lenka and Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 (2019) Cascade aza-Prins reactions. Advances in Heterocyclic Chemistry. Academic Press, pp. 251-278. (doi:https://doi.org/10.1016/bs.aihch.2019.10.006)
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Abstract
Saturated nitrogen-containing heterocycles are the basis of a plethora of natural products, including alkaloids and aza-sugars, and a recent survey also demonstrated that the piperidine ring is the most abundant nitrogen-containing heterocycle in FDA-approved pharmaceutically active and commercially available drugs, being found in 72 drugs. The aza-Prins and related reactions have emerged as a rapid and highly efficient method for the preparation of 6-membered nitrogen-containing heterocycles. This chapter reviews recent developments in the aza-Prins reaction, particularly focussing on reports since 2000.
Item Type: | Book Section |
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Additional Information: | Published in Advances in Heterocyclic Chemistry, ISSN 0065-2725. |
Uncontrolled Keywords: | aza-Prins reaction, Lewis acid, piperidine, heterocyclic chemistry, Prins reaction, natural product |
Subjects: | Q Science > QD Chemistry |
Faculty / School / Research Centre / Research Group: | Faculty of Engineering & Science Faculty of Engineering & Science > School of Science (SCI) |
Last Modified: | 21 Oct 2020 22:31 |
URI: | http://gala.gre.ac.uk/id/eprint/26537 |
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