Skip navigation

Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue

Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue

Li, Yang and Fivaz, Marc ORCID: 0000-0003-1003-7934 (2008) Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue. BioEssays : news and reviews in molecular, cellular and developmental biology, 30 (10). pp. 929-933. ISSN 1521-1878 (Print), 1475-147X (Online) (doi:https://doi.org/10.1002/bies.20824)

[img] PDF (Publisher's PDF)
18512 FIVAZ_Feedback_Mediated_Neuronal_Competition_2008.pdf - Published Version
Restricted to Registered users only

Download (117kB) | Request a copy

Abstract

Proper wiring of the nervous system requires tight control of the number of nerve terminals that innervate a target tissue. Recent work by Deppmann et al., now suggests that this is achieved by feedback-mediated neuronal competition for target-derived survival cues. The authors' model is inspired by the theory for pattern formation based on self-activation and lateral inhibition, proposed by Meinhardt and Gierer more than 30 years ago.

Item Type: Article
Uncontrolled Keywords: feedback, signalling, synapse, neurobiology
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science
Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified: 09 Oct 2021 04:46
URI: http://gala.gre.ac.uk/id/eprint/18512

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics