Li, Yang and Fivaz, Marc ORCID: https://orcid.org/0000-0003-1003-7934 (2008) Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue. BioEssays : news and reviews in molecular, cellular and developmental biology, 30 (10). pp. 929-933. ISSN 1521-1878 (Print), 1475-147X (Online) (doi:10.1002/bies.20824)

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Abstract

Proper wiring of the nervous system requires tight control of the number of nerve terminals that innervate a target tissue. Recent work by Deppmann et al., now suggests that this is achieved by feedback-mediated neuronal competition for target-derived survival cues. The authors' model is inspired by the theory for pattern formation based on self-activation and lateral inhibition, proposed by Meinhardt and Gierer more than 30 years ago.

Item Type:	Article
Uncontrolled Keywords:	feedback, signalling, synapse, neurobiology
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified:	09 Oct 2021 04:46
URI:	http://gala.gre.ac.uk/id/eprint/18512

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