Visendi, Paul, Batley, Jacqueline and Edwards, David (2013) Next generation sequencing and germplasm resources. Genomics of Plant Genetic Resources. Springer, Dordrecht, Holland, pp. 369-390. ISBN 978-9400775718 (doi:10.1007/978-94-007-7572-5_15)

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Abstract

DNA sequencing technology is advancing at an astounding rate, with rapid increases in data volumes and quality combined with reducing costs. The availability of this technology opens novel avenues for the analysis of plant germplasm resources. Where previous studies analysed a limited number of phenotypic or molecular genetic markers, it is now possible to re-sequence whole genomes to characterise diversity at a resolution of each nucleotide. Current approaches combine high resolution genetic markers with genome sequencing both for reference assembly and genotyping by sequencing. As next generation sequencing technologies continue to advance, we approach the potential to catalogue and characterise all genome variations across

Item Type:	Book Section
Uncontrolled Keywords:	Genome sequencing; Pangenome; Illumina; Ion Torrent; AB SOLiD; Pacific biosciences; Oxford nanopore; Roche 454; Single nucleotide polymorphisms; Bioinformatics
Subjects:	S Agriculture > S Agriculture (General)
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > Natural Resources Institute Faculty of Engineering & Science > Natural Resources Institute > Agriculture, Health & Environment Department Faculty of Engineering & Science > Natural Resources Institute > Molecular Virology and Entomology Research Group
Last Modified:	02 Nov 2017 17:27
URI:	http://gala.gre.ac.uk/id/eprint/17913

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