Varghese, George K., Diana, K. J. and Habtemariam, Solomon (2014) In vitro studies on indigenous medicine for urolithiasis: Efficacy of aqueous extract of Aerva lanata (Linn.) Juss. Ex Schult on growth inhibition of calcium hydrogen phosphate dihydrate. The Pharma Innovation International Journal, 3 (1). pp. 92-100. ISSN 2349-8242 (Print), 2277-7695 (Online)

Preview

PDF (Publisher PDF) 13416_Habtemariam_In vitro studies on indigenous medicine (pub PDF) 2014.pdf - Published Version Available under License Creative Commons Attribution Non-commercial. Download (1MB) | Preview

Abstract

Aerva lanata (L.) Juss. ex Schult., is one of the medicinal plants widely used by traditional healers for the treatment of urolithiasis. A perusal of literature revealed that no studies have so far been undertaken to evaluate its efficacy against Calcium Hydrogen Phosphate Dihydrate (CHPD) or brushite type urinary crystals. Hence, an attempt is made in this study to assess the validity of this indigenous knowledge by using in vitro single diffusion gel growth technique. The morphology of CHPD crystals was studied by microscopy. The structural and chemical changes of the treated crystals were assessed by FTIR, XRD, TGA/DTA and SEM/ EDX analysis. The study revealed that aqueous extract of Aerva lanata is very effective to make structural changes and reduction in size of the brushite type urinary crystals.

Item Type:	Article
Uncontrolled Keywords:	Urolithiasis, Aerva lanata, Calcium hydrogen phosphate Dihydrate, SEM, EDX, FT-IR, TGA/DTA and XRD.
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	Publisher
Last Modified:	15 Nov 2021 12:14
URI:	http://gala.gre.ac.uk/id/eprint/13416

Actions (login required)

View Item

Downloads