The preparation of solid core drug delivery systems (SCDDS) for the biomolecular delivery
Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir and Mitchell, John ORCID: 0000-0003-2945-3292 (2014) The preparation of solid core drug delivery systems (SCDDS) for the biomolecular delivery. In: 14th European Meeting on Supercritical Fluids (EMSF), 18-21 May 2014, Marseille, France.
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Abstract
In this study a solid core drug delivery system (SCDDS) is prepared with silica as a model core, fatty acid as a shell material and supercritical fluid technology as the process. SCDDS can be developed as targeted delivery systems or as sustained/controlled release platforms. SCDDS are coated with fatty acids using supercritical fluid technology (SCFT), allowing the creation of nano-particulate and micro-particulate delivery systems. The operating conditions of low temperature and pressure used to formulate these systems make it attractive for pharmaceutical research, especially for thermo-labile or sensitive bio-materials.
Item Type: | Conference or Conference Paper (Paper) |
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Uncontrolled Keywords: | Solid core drug delivery system, Supercritical fluid, Biomolecules, Fatty acids, Oral delivery |
Faculty / School / Research Centre / Research Group: | Faculty of Engineering & Science > School of Science (SCI) |
Last Modified: | 17 Oct 2016 09:13 |
URI: | http://gala.gre.ac.uk/id/eprint/13414 |
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