Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Guesné, Sebastien J.J., Hursthouse, Michael B. and Coles, Simon J. (2003) [Letter] The aza-silyl-prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines. Synlett (11). pp. 1740-1742. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:https://doi.org/10.1055/s-2003-41434)

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Abstract

Reaction of 4-trimethylsilyl-3-butenyl-1-amines with aldehydes under mild Lewis acid conditions gives substituted tetrahydropyridines in excellent yields and with excellent trans diastereoselectivity.

Item Type:	Article
Uncontrolled Keywords:	Prins reaction, aldehydes, indium trichloride
Subjects:	Q Science > QD Chemistry
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	Organisation
Last Modified:	21 Oct 2020 22:31
URI:	http://gala.gre.ac.uk/id/eprint/10585

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