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A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles

A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles

Dobbs, Adrian P. ORCID logoORCID: https://orcid.org/0000-0002-7241-7118, Guesné, Sebastien J. J., Martinović, Saša, Coles, Simon J. and Hursthouse, Michael B. (2003) A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles. The Journal of Organic Chemistry, 68 (20). pp. 7880-7883. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:10.1021/jo034981k)

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Abstract

A versatile and high-yielding indium trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with aldehydes or epoxides is described as a rapid route to a range of unsaturated heterocycles. The excellent diastereoselectivity observed offers a method of wide scope and generality.

Item Type: Article
Uncontrolled Keywords: indium trichloride, Prins reaction, silyl-Prins reaction
Subjects: Q Science > QD Chemistry
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science > School of Science (SCI)
Related URLs:
Last Modified: 21 Oct 2020 22:31
URI: http://gala.gre.ac.uk/id/eprint/10582

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