1,4-Benzodiazipine-2-ones in medicinal chemistry
Spencer, John, Rathnam, Rajendra P. and Chowdhry, Babur Z. (2010) 1,4-Benzodiazipine-2-ones in medicinal chemistry. Future Medicinal Chemistry, 2 (9). pp. 1441-1449. ISSN 1756-8919 (doi:10.4155/fmc.10.226)Full text not available from this repository.
1,4-benzodiazepin-2-ones have applications in many areas of medicinal chemistry that are not restricted to ‘classical’ CNS treatments such as sedatives, epilepsy and muscle relaxants. We will describe selected examples of 1,4-benzodiazepin-2-ones in other areas of medicinal chemistry including uses as G-protein-coupled receptor antagonists, enzyme inhibitors and anticancer agents. Examples from our group will mainly show the use of palladacycle complexes of 1,4-benzodiazepin-2-ones as anticancer agents.
|Uncontrolled Keywords:||G-protein coupled receptor antagonists, enzyme inhibitors, anticancer agents, palladacycle complexes, synthesis|
|Subjects:||Q Science > QD Chemistry
R Medicine > R Medicine (General)
|Faculty / Department / Research Groups:||Faculty of Engineering & Science > Department of Life & Sports Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
|Last Modified:||17 Oct 2016 09:10|
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