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Antioxidant and cytoprotective activity of leaves of Peltiphyllum peltatum (Torr.) Engl.

Antioxidant and cytoprotective activity of leaves of Peltiphyllum peltatum (Torr.) Engl.

Habtemariam, Solomon and Jackson, Caroline (2007) Antioxidant and cytoprotective activity of leaves of Peltiphyllum peltatum (Torr.) Engl. Food Chemistry, 105 (2). p. 498. ISSN 0308-8146 (doi:10.1016/j.foodchem.2007.03.073)

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Abstract

The antioxidant potential of fresh leaves of Peltiphyllum peltatum (Torr.) Engl. (Saxfragaceae) was analysed by measuring scavenging potential against l,l'-diphenyl-2-picrylhydrazyl (DPPH center dot) and hydroxyl radicals (W), reducing power, inhibition of lipid peroxidation and protection of cultured cells from a lethal dose of hydrogen peroxide (H2O2). In all chemical assays used, the crude ethanolic extract of leaves of P. peltatum, which contained 21.8 +/- 1.7% (w/w, n = 3) of total phenols, was as effective as the standard antioxidant compound, rutin. Fractionation of the crude extract with solvent of increasing polarity (namely, petroleum ether, chloroform, ethyl acetate, butanol and water) led to identification of the active fractions (ethyl acetate and butanol fractions). The crude extract and its active fractions, but not rutin, protected cultured RAW 264.7 macrophages from a lethal dose Of H2O2.

Item Type: Article
Uncontrolled Keywords: Peltiphyllum peltatum, saxifragaceae, antioxidant, radical scavenging, reducing power, phenol content, Cytoprotection, DPPH, hydroxyl radical
Subjects: Q Science > QD Chemistry
T Technology > TX Home economics
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 09 Dec 2016 15:46
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/2506

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