Items where Faculty / School / Research Centre / Research Groups is "Pharmaceutical and Medicinal Science Research Group"

University Structure (17)
- Faculty of Engineering & Science (17)
  - Medway Centre for Pharmaceutical Science (17)
    - Pharmaceutical and Medicinal Science Research Group (17)

Group by: Date | Creators | Item Type | Uncontrolled Keywords | No Grouping

%HIA absorption aminopropyl column Amorphous Anopheles coluzzii antibiotic batch sulphoalkylation reaction bile salt biosurfactant continuous flow conditions Continuous manufacturing Continuous tank reactor synthesis copper ligand design C−H activation catalysis radical DFT EPR propargylamines Cyclodextrin Cyclodextrins cytokine release syndrome cytokine storm cytokine storm syndrome cytokines Deformation diazines drug delivery Elastomer endectocides Energy dispersive X-ray fecundity flow-through cells Flux gut microbiome Heckel equation HIA human intestinal absorption hydrogels Hydrogenation Hydrophobicity Isophorone Ivermectin Linear regression lipophilicity Metabolic profiling metabolite Metabolomics Metabonomics micellar liquid chromatography MLC multiple linear regression NaDC NMR (nuclear magnetic resonance) spectroscopy nucleobase Oligomer Oral strips PDMS permeation pharmacokinetics Pharmacometabolomics Pharmacometabonomics Plasma Pmw Prediction of PK self-assembly Silicone sodium deoxycholate static diffusion cells stomach Structure elucidation sulphoalkyl ether-β-cyclodextrin Sulphobutylether β-cyclodextrins Surface analysis survival Tebbe reagent Total synthesis triazines True density urine vector control Yield pressure

Number of items at this level: 80.

%HIA

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

absorption

aminopropyl column

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2019) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomedical Chromatography, 33 (7):e4515. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4515)

Amorphous

Maniruzzaman, Mohammed, Farias, Smirna, Slipper, Ian J., Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Chowdhry, Babur Z., Nair, Arun and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2016) Development and optimization of ketoconazole oral strips by means of continuous hot-melt extrusion processing. Journal of Pharmacy and Pharmacology, 68 (7). pp. 890-900. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/jphp.12569)

Anopheles coluzzii

Shepherd-Gorringe, Monique, Pettit, Marie Wendy and Hawkes, Frances ORCID: 0000-0002-0964-3702 (2024) Lethal and sublethal impacts of membrane-fed ivermectin are concentration-dependant in Anopheles coluzzii. Parasites and Vectors. ISSN 1756-3305 (In Press)

antibiotic

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

batch sulphoalkylation reaction

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

bile salt

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2018) Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption. Biomedical Chromatography, 32 (12):e4351. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4351)

biosurfactant

continuous flow conditions

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

Continuous manufacturing

Continuous tank reactor synthesis

Mitchell, John ORCID: 0000-0003-2945-3292 , Wicks, Stephen, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Waters, Laura and Ehiwe, Tammy (2015) Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins. International Journal of Pharmaceutics, 495 (2). pp. 862-868. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.039)

copper ligand design C−H activation catalysis radical DFT EPR propargylamines

Devonport, Jack, Sully, Lauren, Boudalis, Athanassios K., Hassell-Hart, Storm, Leech, Matthew C., Lam, Kevin ORCID: 0000-0003-1481-9212 , Abdul-Sada, Alaa, Tizzard, Graham J., Coles, Simon J., Spencer Evans, John, Vargas, Alfredo and Kostaki, George E. (2021) Room temperature Cu(II) radical-triggered Alkyne C−H activation. Journal of the American Chemical Society AU. ISSN 2691-3704 (Print), 2691-3704 (Online) (doi:https://doi.org/10.1021/jacsau.1c00310)

Cyclodextrin

John Mitchell (US 14/333,417) (2015) WO2015008066A1: Cyclodextrin US 20150025023 A1. .

Cyclodextrins

cytokine release syndrome

Leach, Michael, and Williams, Paul, University of Greenwich (2023) Diazine and triazine compounds to treat cytokine storm syndrome US 2023/0165869 A1. US2023/0165869A1.

cytokine storm

Leach, Michael, and Williams, Paul, University of Greenwich (2021) Diazine and triazine compounds to treat cytokine storm syndrome. WO2016198878A1.

cytokine storm syndrome

Leach, Michael, and Williams, Paul, University of Greenwich (2023) Diazine and triazine compounds to treat cytokine storm syndrome US 2023/0165869 A1. US2023/0165869A1.

cytokines

Leach, Michael, and Williams, Paul, University of Greenwich (2021) Diazine and triazine compounds to treat cytokine storm syndrome. WO2016198878A1.

Deformation

Hooper, D., Clarke, F.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2016) A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt. Journal of Nanomedicine and Nanotechnology, 7 (381). p. 2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000381)

diazines

Leach, Michael, and Williams, Paul, University of Greenwich (2021) Diazine and triazine compounds to treat cytokine storm syndrome. WO2016198878A1.

drug delivery

Scognamiglio, Pasqualina Liana, Riccardi, Claudia, Palumbo, Rosanna, Gale, Thomas F., Musumeci, Domenica ORCID: 0000-0001-7624-1933 and Roviello, Giovanni N. ORCID: 0000-0002-6978-542X (2023) Self-assembly of thyminyl l-tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems. Journal of Nanostructure in Chemistry, 2023. pp. 1-19. ISSN 2008-9244 (Print), 2193-8865 (Online) (doi:https://doi.org/10.1007/s40097-023-00523-7)

Elastomer

Minicone, Fabrizio, Attrill, Robin, Hodgson, Michael, Wheelhouse, Katherine and Dobbs, Adrian ORCID: 0000-0002-7241-7118 (2018) First total synthesis and structural confirmation of C13-Butylrubber Oligomers. European Journal of Organic Chemistry, 2018 (25). pp. 3271-3275. ISSN 1434-193X (Print), 1099-0690 (Online) (doi:https://doi.org/10.1002/ejoc.201800937)

endectocides

Energy dispersive X-ray

fecundity

flow-through cells

Flux

Waters, Laura J., Finch, Catherine V., Bhuiyan, A.K.M. Mehedi H., Hemming, Karl and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Effect of plasma surface treatment of poly (dimethylsiloxane) on the permeation of pharmaceutical compounds. Journal of Pharmaceutical Analysis, 7 (5). pp. 338-342. ISSN 2095-1779 (doi:https://doi.org/10.1016/j.jpha.2017.05.003)

gut microbiome

Heckel equation

HIA

human intestinal absorption

hydrogels

Hydrogenation

Hydrophobicity

Isophorone

Ivermectin

Linear regression

lipophilicity

Metabolic profiling

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

metabolite

Metabolomics

Metabonomics

micellar liquid chromatography

MLC

multiple linear regression

NaDC

NMR (nuclear magnetic resonance) spectroscopy

nucleobase

Oligomer

Oral strips

PDMS

permeation

pharmacokinetics

Pharmacometabolomics

Pharmacometabonomics

Plasma

Pmw

Prediction of PK

self-assembly

Silicone

sodium deoxycholate

static diffusion cells

stomach

Structure elucidation

sulphoalkyl ether-β-cyclodextrin

Curadev Pharma Private Ltd (2019) Cyclodextrin. US10239961B2.

Sulphobutylether β-cyclodextrins

Surface analysis

survival

Tebbe reagent

Total synthesis

triazines

Leach, Michael, and Williams, Paul, University of Greenwich (2021) Diazine and triazine compounds to treat cytokine storm syndrome. WO2016198878A1.

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