bioavailability

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

chitosan

Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125323)

citrus essential oil

Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.126146)

drug delivery strategies

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

exopolysaccharides

Chen, Lian, Wang, Dong ORCID: https://orcid.org/0000-0001-5214-2973, Liu, Wei, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Gu, Qing ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Immunomodulation of exopolysaccharide produced by Lacticaseibacillus rhamnosus ZFM216 in cyclophosphamide-induced immunosuppressed mice by modulating gut microbiota. International Journal of Biological Macromolecules, 283 (Part 2):137619. ISSN 0141-8130 (Print), 1757-448X (Online) (doi:10.1016/j.ijbiomac.2024.137619)

flavonoids

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

fusiforme

Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2022.11.030)

gastrointestinal conditions

Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125030)

gut microbiota

Chen, Lian, Wang, Dong ORCID: https://orcid.org/0000-0001-5214-2973, Liu, Wei, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Gu, Qing ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Immunomodulation of exopolysaccharide produced by Lacticaseibacillus rhamnosus ZFM216 in cyclophosphamide-induced immunosuppressed mice by modulating gut microbiota. International Journal of Biological Macromolecules, 283 (Part 2):137619. ISSN 0141-8130 (Print), 1757-448X (Online) (doi:10.1016/j.ijbiomac.2024.137619)

Gynura divaricata (L.) DC polysaccharide

Zhu, YuZhu, Wang, Dong, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Hypoglycemic effects of Gynura Divaricata (L.) DC Polysaccharide and action mechanisms via modulation of gut microbiota in diabetic mice. Journal of Agricultural and Food Chemistry. ISSN 0021-8561 (Print), 1520-5118 (Online) (doi:10.1021/acs.jafc.4c00626)

Huyou pectin

Huang, Yu-Ting, Zhang, Xu, Ding, Xi-ming, Wu, Ru-Qin, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2025) Antioxidant, hypoglycemic and hypolipidemic activities of pectins from Citrus aurantium ‘Changshanhuyou’. International Journal of Biological Macromolecules, 337 (Part 1):149501. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:10.1016/j.ijbiomac.2025.149501)

hypoglycemic activity

Huang, Yu-Ting, Zhang, Xu, Ding, Xi-ming, Wu, Ru-Qin, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2025) Antioxidant, hypoglycemic and hypolipidemic activities of pectins from Citrus aurantium ‘Changshanhuyou’. International Journal of Biological Macromolecules, 337 (Part 1):149501. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:10.1016/j.ijbiomac.2025.149501)

hypoglycemic effect

Zhu, YuZhu, Wang, Dong, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Hypoglycemic effects of Gynura Divaricata (L.) DC Polysaccharide and action mechanisms via modulation of gut microbiota in diabetic mice. Journal of Agricultural and Food Chemistry. ISSN 0021-8561 (Print), 1520-5118 (Online) (doi:10.1021/acs.jafc.4c00626)

hypolipidemic activity

Huang, Yu-Ting, Zhang, Xu, Ding, Xi-ming, Wu, Ru-Qin, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2025) Antioxidant, hypoglycemic and hypolipidemic activities of pectins from Citrus aurantium ‘Changshanhuyou’. International Journal of Biological Macromolecules, 337 (Part 1):149501. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:10.1016/j.ijbiomac.2025.149501)

immunomodulatory effect

Chen, Lian, Wang, Dong ORCID: https://orcid.org/0000-0001-5214-2973, Liu, Wei, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Gu, Qing ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Immunomodulation of exopolysaccharide produced by Lacticaseibacillus rhamnosus ZFM216 in cyclophosphamide-induced immunosuppressed mice by modulating gut microbiota. International Journal of Biological Macromolecules, 283 (Part 2):137619. ISSN 0141-8130 (Print), 1757-448X (Online) (doi:10.1016/j.ijbiomac.2024.137619)

intestinal flora

Zhu, YuZhu, Wang, Dong, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2024) Hypoglycemic effects of Gynura Divaricata (L.) DC Polysaccharide and action mechanisms via modulation of gut microbiota in diabetic mice. Journal of Agricultural and Food Chemistry. ISSN 0021-8561 (Print), 1520-5118 (Online) (doi:10.1021/acs.jafc.4c00626)

Lacticaseibacillus rhamnosus

Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125030)

microcapsule

Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125030)

nanoparticledelivery

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

neurodegenerative diseases

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

neurological disorders

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

neuroprotection

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

pickering emulsions

Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.126146)

polysaccharides

Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2022.11.030)

purification

Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2022.11.030)

rutin

Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Hassan, Halimatu, Guo, Jin, Xu, Yan, Zhang, Pengxia, Yuan, Linhong, Zhou, Tao and Chen, Ruoli (2026) From gut to brain: formulation and transporter-guided approaches to maximise rutin central nervous system delivery. Nutritional Neuroscience: An International Journal on Nutrition, Diet and Nervous System. ISSN 1028-415X (Print), 1476-8305 (Online) (doi:10.1007/s40618-025-02730-1)

Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125323)

Sargassum

Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2022.11.030)

soybean protein isolate

Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.125323)

soybean protein isolate-chitosan hydrochloride

Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: https://orcid.org/0000-0001-5214-2973, Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:10.1016/j.ijbiomac.2023.126146)