Items where Author is "Mitchell, John C."

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%HIA 2D correlation 5-methoxytryptamine ab initio calculations absorption accuracy accuracy. precision aminopropyl column amitriptyline amorphous antigen presenting cells APCs asymmetric catalysis Attachment techniques BCA bicinchoninic acid assay bile salt biosurfactant Bovine haemoglobin buccal delivery Buccal mucosa C-13 catalysts cationic poly(NIPAM/BA/4-vinylpyridine) CD Ceftazidime chip-based nanoelectrospray Chitosan chloropyrimidines Circular dichroism Colloidal microgels Cotion samples crystalline cyclic di-amino acid peptides Differential scanning Calorimetry Diffuse reflectance visible spectroscopy diffuse reflection spectroscopy dispersion DRS DRUV spectroscopy Durham tube dynamic nuclear polarisation electronic tongue enantiomeric excess Enteric Enzyme inhibitor fatty acids flow-through cells Flux Formulation glutathione-S-transferase (GST) Green GST–GFP heteronuclear HIA hot-melt extrusion human intestinal absorption Human intestinal absorption (HIA) hydration hydrogels Hydrophobicity identification imidazolide couplings immobilisation in vitro inclusion complexes Indomethacin Insulin IPTG isothermal microcalorimetry kinetic data kinetic modelling lamina propria lipophilicity LP lyophilisation lyophilised wafers MALDI-TOF maternally derived antibodies matrices matrix assisted laser desorption ionisation time o MDA melting point depression membrane dialysis Methyl-β-cyclodextrin micellar liquid chromatography Microgel particles MLC mole fraction composition molecules mouth mucoadhesion multiple linear regression multivariate data processing N-15 NaDC Nanoparticles networks NMR NMR chemical shifts nonisothermal reaction calorimetry Olanzapine paraben particles PCS PDMS perichromism permeation Permeation enhancement Peyer’s patch Pharmaceutical pharmaceutical products pharmacokinetics Plasma Pmw Polycaprolactone polymers Polymorphic transformation Powder X-ray diffraction PP prediction protein protein delivery quantitative MS/MS Raman chemical images Raman line mapping Raman maps reaction conditions reference state RH perfusion sample-sample SANS SDS PAGE silica Silicone silicone membranes skin permeability small angle neutron scattering smart fabrics SMART wound dressings sodium deoxycholate sodium dodecyl sulphate polyacrylamide gel electro Solubility solubility parameter Solvent extraction spin-lattice relaxation spray drying static diffusion cells stomach Storage stability Sulfanilamide Supercritical Supercritical carbon dioxide Supercritical fluid extraction of emulsions supercritical fluids surfactant synthetic protein taste masking temperature Thermal stability thermodynamic activity thermodynamic parameters thiolated-chitosan time dilemma two-dimensional correlation ultraviolet-visible spectroscopy univariate data processing vaccine vaccine delivery systemsenteric VDS veins vibrational spectra wound healing X-ray crystallography X-ray structure Xerogel

Number of items: 202.

%HIA

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2018) Formation of a bile salt-drug hydrogel to predict human intestinal absorption. Journal of Pharmaceutical Sciences, 108 (1). pp. 279-287. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2018.10.005)

2D correlation

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Analyzing Raman maps of pharmaceutical products by sample-sample two-dimensional correlation. Applied Spectroscopy, 59 (5). pp. 630-638. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/0003702053946047)

5-methoxytryptamine

Alfazema, Louisa N., Richards, Don S., Gélébart, Sylvie, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Rapid, accurate and precise quantitative drug analysis: comparing liquid chromatography tandem mass spectrometry and chip-based nanoelectrospray ionisation mass spectrometry. European Journal of Mass Spectrometry, 11 (4). pp. 393-402. ISSN 1469-0667 (Print), 1356-1049 (Online) (doi:https://doi.org/10.1255/ejms.772)

ab initio calculations

Mendham, Andrew P., Potter, Brian S., Palmer, Rex A., Dines, Trevor J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Withnall, Robert and Chowdhry, Babur Z. (2009) Vibrational spectra and crystal structure of the di-amino acid peptide cyclo(L-Met-L-Met): Comparison of experimental data and DFT calculations. Journal of Raman Spectroscopy, 41 (2). pp. 148-159. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2426)

Mendham, Andrew P., Dines, Trevor J., Withnall, Robert, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Chowdhry, Babur Z. (2009) Vibrational spectroscopic studies of the structure of di-amino acid peptides. Part II: cyclo(L-Asp-L-Asp) in the solid state and in aqueous solution. Journal of Raman Spectroscopy, 40 (11). pp. 1498-1507. ISSN 0377-0486 (Print), 1097-4555 (Online) (doi:https://doi.org/10.1002/jrs.2307)

absorption

Waters, Laura J., Shokry, Dina S., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The use of bile salt micelles for the prediction of human intestinal absorption. Journal of Pharmaceutical Sciences, 105 (12). pp. 3611-3614. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:https://doi.org/10.1016/j.xphs.2016.09.007)

Cornelius, Victoria J., Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2006) The use of colloidal microgels for the controlled delivery of proteins and peptides. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130Y (6413). Society of Photo-Optical Instrumentation Engineers (SPIE), Bellingham, Washington USA. ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712578)

accuracy

Pérez, Manuel, Peakman, Torren M., Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Iñaki (2006) Accuracy vs time dilemma on the prediction of NMR chemical shifts: a case study (chloropyrimidines). The Journal of Organic Chemistry, 71 (8). pp. 3103-3110. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo0600149)

accuracy. precision

aminopropyl column

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M.B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2019) Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase. Biomedical Chromatography, 33 (7):e4515. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4515)

amitriptyline

amorphous

Major, Patrick J., Wicks, Stephen R., Alexander, Bruce D. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2011) Perichromism: a novel, rapid, spectroscopic technique to distinguish between amorphous and crystalline material. Applied Spectroscopy, 65 (12). pp. 1357-1362. ISSN 0003-7028 (Print), 1943-3530 (Online) (doi:https://doi.org/10.1366/11-06422)

antigen presenting cells

Pettit, Marie, Dyer, Paul D.R., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Griffiths, Peter C. ORCID: 0000-0002-6686-1271 , Alexander, Bruce, Cattoz, Beatrice, Heenan, Richard K., King, Stephen M., Schweins, Ralf, Pullen, Frank, Wicks, Stephen R. and Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 (2014) Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS). International Journal of Pharmaceutics, 468 (1-2). pp. 264-271. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2014.03.046)

APCs

asymmetric catalysis

Sciabola, Simone, Alex, Alexander, Higginson, Paul D., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Morao, Inaki (2005) Theoretical prediction of the enantiomeric excess in asymmetric catalysis. An alignment-independent molecular interaction field based approach. The Journal of Organic Chemistry, 70 (22). pp. 9025-9027. ISSN 0022-3263 (Print), 1520-6904 (Online) (doi:https://doi.org/10.1021/jo051496b)

Attachment techniques

Majcen, Natasa, Mohsen, Reham, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2018) The development of a novel smart material based on colloidal microgels and cotton. Advances in Colloid and Interface Science, 256. pp. 193-202. ISSN 0001-8686 (Print), 1095-7103 (Online) (doi:https://doi.org/10.1016/j.cis.2018.04.005)

BCA

bicinchoninic acid assay

bile salt

Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2018) Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption. Biomedical Chromatography, 32 (12):e4351. ISSN 0269-3879 (Print), 1099-0801 (Online) (doi:https://doi.org/10.1002/bmc.4351)

biosurfactant

Bovine haemoglobin

Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Coleman, Nichola J. and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2016) The thermal and storage stability of bovine haemoglobin by ultra violet–visible and circular dichroism spectroscopies. Journal of Pharmaceutical Analysis, 6 (4). pp. 242-248. ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2016.02.004)

buccal delivery

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) In vitro characterisation of chitosan based xerogels for potential buccal delivery of proteins. Carbohydrate Polymers, 89 (3). pp. 935-941. ISSN 0144-8617 (doi:https://doi.org/10.1016/j.carbpol.2012.04.039)

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)

Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2011) Development and physico-mechanical characterisation of lyophilised chitosan wafers as potential protein drug delivery systems via the buccal mucosa. Colloids and Surfaces B: Biointerfaces, 91. pp. 258-265. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2011.11.004)

Buccal mucosa

Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Pawar, Harshavardhan and Ayensu, Isaac (2014) Functional characterisation and permeation studies of lyophilised thiolated chitosan xerogels for buccal delivery of insulin. Protein & Peptide Letters, 21 (11). pp. 1163-1175. ISSN 0929-8665 (Print), 1875-5305 (Online) (doi:https://doi.org/10.2174/0929866521666140805124403)

C-13

Day, Iain, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Co-acquisition of hyperpolarised 13C and 15N NMR spectra. Magnetic Resonance in Chemistry, 45 (12). pp. 1018-1021. ISSN 0749-1581 (Print), 1097-458X (Online) (doi:https://doi.org/10.1002/mrc.2090)

catalysts

Bright, Robert, Dale, David J., Dunn, Peter J., Hussain, Farhat, Kang, Ying, Mason, Clive, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) Identification of new catalysts to promote imidazolide couplings and optimisation of reaction conditions using kinetic modelling. Organic Process Research & Development, 8 (6). pp. 1054-1058. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op049874m)

cationic poly(NIPAM/BA/4-vinylpyridine)

Pinkrah, Victoria T., Beezer, Anthony E., Chowdry, Babur Z., Gracia, Louise H., Cornelius, Victoria J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Castro-Lopez, Vanessa and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Swelling of cationic polyelectrolyte colloidal microgels: thermodynamic considerations. Colloids and Surfaces A: Physiochemical and Engineering Aspects, 262 (1-3). pp. 76-80. ISSN 0927-7757 (doi:https://doi.org/10.1016/j.colsurfa.2005.04.022)

CD

Ceftazidime

Hills, Andrew K., Gaisford, Simon, Beezer, Anthony E., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Connor, Joseph A. and Theophilus, Andrew L. (2003) Isothermal microcalorimetry as a tool to study solid-vapour interactions: design and testing of a novel hydration apparatus. Thermochimica Acta, 399 (1-2). pp. 91-98. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00449-5)

chip-based nanoelectrospray

Chitosan

chloropyrimidines

Circular dichroism

Colloidal microgels

Cotion samples

crystalline

cyclic di-amino acid peptides

Differential scanning Calorimetry

Ehiwe, Tracy O., Alexander, Bruce D, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Waters, Laura J. (2016) Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy. Journal of Pharmaceutical Analysis, 6 (3). ISSN 2095-1779 (Print), 2214-0883 (Online) (doi:https://doi.org/10.1016/j.jpha.2015.12.002)

Diffuse reflectance visible spectroscopy

diffuse reflection spectroscopy

dispersion

DRS

DRUV spectroscopy

Durham tube

dynamic nuclear polarisation

Day, Iain J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Davis, Adrian L. (2007) Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times. Journal of Magnetic Resonance, 187 (2). pp. 216-224. ISSN 1090-7807 (doi:https://doi.org/10.1016/j.jmr.2007.04.015)

electronic tongue

Maniruzzaman, Mohammed, Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Bonnefille, Marion, Arranyos, Attila, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2011) Taste masking of paracetamol by hot-melt extrusion: An in vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 80 (2). pp. 433-442. ISSN 0939-6411 (doi:https://doi.org/10.1016/j.ejpb.2011.10.019)

enantiomeric excess

Enteric

Enzyme inhibitor

fatty acids

Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Bhomia, Ruchir, Mitchell, John C. ORCID: 0000-0003-2945-3292 , Coleman, Nichola J., Douroumis, Dennis ORCID: 0000-0002-3782-0091 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2013) Study of the effect of pressure on melting behavior of saturated fatty acids in liquid or supercritical carbon dioxide. Journal of Chemical & Engineering Data, 58 (6). pp. 1861-1866. ISSN 0021-9568 (Print), 1520-5134 (Online) (doi:https://doi.org/10.1021/je400260c)

flow-through cells

Flux

Waters, Laura J., Finch, Catherine V., Bhuiyan, A.K.M. Mehedi H., Hemming, Karl and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Effect of plasma surface treatment of poly (dimethylsiloxane) on the permeation of pharmaceutical compounds. Journal of Pharmaceutical Analysis, 7 (5). pp. 338-342. ISSN 2095-1779 (doi:https://doi.org/10.1016/j.jpha.2017.05.003)

Formulation

Rudrangi, Shashi Ravi Suman, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Wicks, Stephen Richard and Alexander, Bruce David (2015) Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties. International Journal of Pharmaceutics, 494 (1). pp. 408-416. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.08.062)

glutathione-S-transferase (GST)

Green

GST–GFP

heteronuclear

HIA

hot-melt extrusion

human intestinal absorption

Human intestinal absorption (HIA)

hydration

hydrogels

Hydrophobicity

identification

imidazolide couplings

immobilisation

in vitro

Waters, Laura J., Dennis, Laura, Bibi, Aisha and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2013) Surfactant and temperature effects on paraben transport through silicone membranes. Colloids and Surfaces B: Biointerfaces, 108. pp. 23-28. ISSN 0927-7765 (doi:https://doi.org/10.1016/j.colsurfb.2013.02.017)

inclusion complexes

Rudrangi, Shashi Ravi Suman, Bhomia, Ruchir, Trivedi, Vivek ORCID: 0000-0001-9304-9214 , Vine, George J., Mitchell, John C. ORCID: 0000-0003-2945-3292 , Alexander, Bruce David and Wicks, Stephen Richard (2015) Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes. International Journal of Pharmaceutics, 479 (2). pp. 381-390. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.01.010)

Indomethacin

Insulin

IPTG

isothermal microcalorimetry

kinetic data

Hoffmann, Wilfried, Kang, Ying, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin ORCID: 0000-0002-1087-2692 (2007) Kinetic data by nonisothermal reaction calorimetry: a model-assisted calorimetric evaluation. Organic Process Research & Development, 11 (1). pp. 25-29. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op060144j)

kinetic modelling

lamina propria

lipophilicity

LP

lyophilisation

lyophilised wafers

MALDI-TOF

maternally derived antibodies

matrices

Cornelius, Victoria J., Majcen, Natasa, Snowden, Martin J. ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 and Voncina, Bojana (2006) Preparation of SMART wound dressings based on colloidal microgels and textile fibres. In: Smart Materials IV (Proceedings Volume). Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE), 64130X (6413). Society of Photo-Optical Instrumentation Engineers (SPIE). ISBN 9780819465214 (doi:https://doi.org/10.1117/12.712573)

matrix assisted laser desorption ionisation time o

MDA

melting point depression

membrane dialysis

Methyl-β-cyclodextrin

micellar liquid chromatography

Microgel particles

MLC

mole fraction composition

molecules

mouth

mucoadhesion

multiple linear regression

multivariate data processing

Sasic, Slobaban, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2004) A comparison of Raman chemical images produced by univariate and multivariate data processing - a simulation with an example from pharmaceutical practice. The Analyst, 129 (11). pp. 1001-1007. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B409879J)

N-15

NaDC

Nanoparticles

Ajiboye, Adejumoke Lara, Trivedi, Vivek ORCID: 0000-0001-9304-9214 and Mitchell, John C. ORCID: 0000-0003-2945-3292 (2017) Preparation of polycaprolactone nanoparticles via supercritical carbon dioxide extraction of emulsions. Drug Delivery and Translational Research. pp. 1-7. ISSN 2190-393X (Print), 2190-3948 (Online) (doi:https://doi.org/10.1007/s13346-017-0422-3)

networks

NMR

NMR chemical shifts

nonisothermal reaction calorimetry

Olanzapine

paraben

particles

PCS

PDMS

perichromism

permeation

Permeation enhancement

Peyer’s patch

Pharmaceutical

pharmaceutical products

pharmacokinetics

Plasma

Pmw

Polycaprolactone

polymers

Polymorphic transformation

Powder X-ray diffraction

PP

prediction

protein

protein delivery

quantitative MS/MS

Raman chemical images

Raman line mapping

Sasic, Slobodan, Clark, Donald A., Mitchell, John C. ORCID: 0000-0003-2945-3292 and Snowden, Martin J. ORCID: 0000-0002-1087-2692 (2005) Raman line mapping as a fast method for analyzing pharmaceutical bead formulations. The Analyst, 130 (11). pp. 1530-1536. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B506523B)

Raman maps

reaction conditions

reference state

RH perfusion

sample-sample

SANS

SDS PAGE

silica

Silicone

silicone membranes

skin permeability

small angle neutron scattering

smart fabrics

Majcen, Natasa, Snowden, Martin ORCID: 0000-0002-1087-2692 , Mitchell, John C. ORCID: 0000-0003-2945-3292 , Cornelius, Victoria J. and Voncina, Bojana (2005) The development of smart fabrics. Journal of Pharmacy and Pharmacology, 57 (Suppl.). S58-S58. ISSN Online ISSN: 2042-7158

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