Items where Author is "Gaffen, John"
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antagonist
Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)
benzotriazepine
Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)
bone
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
CCK
Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)
CCK2
Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)
cells
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
gastrin
Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)
growth
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
metastasis
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
monoclonal-antibody
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
osteoprotegerin
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
protein
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
pthrp
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
ramps
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)
specificity
McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:https://doi.org/10.1021/jm0707626)