antagonist

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:10.1016/j.bmc.2007.12.047)

benzotriazepine

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:10.1016/j.bmc.2007.12.047)

bone

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

CCK

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:10.1016/j.bmc.2007.12.047)

CCK2

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:10.1016/j.bmc.2007.12.047)

cells

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

gastrin

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:10.1016/j.bmc.2007.12.047)

growth

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

metastasis

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

monoclonal-antibody

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

osteoprotegerin

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

protein

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

pthrp

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

ramps

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)

specificity

McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Gaffen, John, Griffin, Eric, Harper, Elaine A., Hull, Robert A.D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M.R., Patel, Dipa, Pether, Michael J., Raynor, Michelle, Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I.M., Sykes, David A., Wright, Paul T. and Xun, Wei (2007) [Letter] Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists. Journal of Medicinal Chemistry, 50 (20). pp. 4789-4792. ISSN 0022-2623 (Print), 1520-4804 (Online) (doi:10.1021/jm0707626)