Skip navigation

Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template

Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template

Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2007.12.047)

Full text not available from this repository.

Abstract

Novel, achiral 1H-1,3,5-benzotriazepine-2,4(3H,5H)-diones have been prepared and structurally characterized. These compounds are potent CCK2 receptor antagonists that display a high degree of selectivity over CCK1 receptors.

Item Type: Article
Additional Information: Erratum to "Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template" [Bioorg. Med. Chem. 16 (2008) 2974–2983] Bioorganic & Medicinal Chemistry, Volume 16, Issue 16, 15 August 2008, Page 7862. Adds John Spencer as corresponding author. No other errata.
Uncontrolled Keywords: CCK, CCK2, gastrin, antagonist, benzotriazepine
Subjects: R Medicine > RM Therapeutics. Pharmacology
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 09 Dec 2016 12:23
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/2222

Actions (login required)

View Item View Item