Larionova, Natalia A., Ondozabal, Jun Miyatake and Couso Cambeiro, Jacobo ORCID: https://orcid.org/0000-0002-7365-7201 (2021) Reduction of electron-deficient alkenes enabled by a photoinduced hydrogen atom transfer. Advanced Synthesis and Catalysis (ASC), 363 (2). pp. 558-564. ISSN 1615-4150 (Print), 1615-4169 (Online) (doi:10.1002/adsc.202000751)

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Abstract

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility.

Item Type:	Article
Uncontrolled Keywords:	Alkenes, transfer hydrogenation, Hydrogen atom transfer, photocatalysis, Photoredox, DFT
Subjects:	Q Science > Q Science (General) T Technology > T Technology (General) T Technology > TP Chemical technology
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science Faculty of Engineering & Science > School of Science (SCI)
Last Modified:	02 Apr 2026 08:47
URI:	https://gala.gre.ac.uk/id/eprint/52792

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