Osman, Muhammad ORCID: 0000-0003-3818-9729, Hesseling, A. C., Beyers, N., Enarson, D. A., Rusen, I. D., Lombard, C. and van Wyk, S. S. (2013) Routine programmatic delivery of isoniazid preventive therapy to children in Cape Town, South Africa. Public Health Action, 3 (3). pp. 199-203. ISSN 2220-8372 (Online) (doi:https://doi.org/10.5588/pha.13.0034)

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Abstract

Setting: Fourteen primary health care facilities in Cape
Town, South Africa.
Objective: To determine the proportion and characteristics of infectious adult tuberculosis (TB) cases that identify children aged <5 years who qualify for isoniazid preventive therapy (IPT), and to determine the proportion of children who initiate and complete IPT.
Design: A retrospective clinical record review conducted as a stratified cluster survey.
Results: Of 1179 records of infectious adult cases, 33.3% had no documentation of contacts. Of the remaining 786 records, 525 contacts aged <5 years were identified, representing 0.7 child contacts per infectious adult case. Older age, male, human immunodeficiency virus (HIV) positive, smear-negative and retreatment TB cases were all associated with no documentation of contacts. Of the 525 child contacts identified, less than half were screened for TB, 141 initiated IPT and 19 completed it. Conclusion: Less than 67% of infectious TB case records had documentation of contacts. Younger, female, HIVnegative and new smear-positive TB cases were more likely to have had contacts identified. Less than 14% of children already initiated on IPT completed 6 months of treatment.

Item Type:	Article
Uncontrolled Keywords:	TB prevention; IPT; programmatic implementation
Subjects:	R Medicine > RJ Pediatrics R Medicine > RS Pharmacy and materia medica
Faculty / School / Research Centre / Research Group:	Faculty of Education, Health & Human Sciences Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified:	22 Mar 2022 10:49
URI:	http://gala.gre.ac.uk/id/eprint/35544

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